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Growth Associated Protein 43 Proteins (GAP43)

The protein encoded by GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. Additionally we are shipping GAP43 Antibodies (230) and GAP43 Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GAP43 29423 P07936
GAP43 2596 P17677
GAP43 14432 P06837
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Top GAP43 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast REACT_Crucian Carp His tag   1 mg Log in to see 56 to 66 Days
$2,526.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,530.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,566.67
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,603.33
Details

GAP43 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,
,
Human , , ,
, ,
Mouse (Murine)
,

Top referenced GAP43 Proteins

  1. Human GAP43 Protein expressed in Escherichia coli (E. coli) - ABIN1098302 : Dent, Meiri: Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behavior. in Journal of neurobiology 1998 (PubMed)
    Show all 2 references for ABIN1098302

  2. Human GAP43 Protein expressed in Human Cells - ABIN2005199 : Sawaguchi, Patricia, Kadhim, Groswasser, Sottiaux, Nishida, Kahn: The relationship between neuronal plasticity and serotonergic neurons in the brainstem of SIDS victims. in Early human development 2003 (PubMed)

More Proteins for Growth Associated Protein 43 (GAP43) Interaction Partners

Human Growth Associated Protein 43 (GAP43) interaction partners

  1. The peripheral neuropathies lead to an initial increase in GAP-43 gene expression as a potential mechanism of regeneration, which is not sustained in neuropathies of long duration.

  2. Results show that PKC (show PRRT2 Proteins)-dependent phosphorylation of GAP43 plays a critical role in regulating postsynaptic gephyrin (show GPHN Proteins) aggregation in developing GABAergic synapses.

  3. increased expression of TH and GAP43 might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation.

  4. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors

  5. The results showed that the decreased GAP-43 levels induced by glutamate (show GRIN1 Proteins) could be partially reversed by the presence of NRG-1beta

  6. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 (show LYPLA1 Proteins) and acyl-protein thioesterase-2 (show LYPLA2 Proteins) with that of proto-oncogene (show RAB1A Proteins) H-ras (show HRAS Proteins) product and growth-associated protein-43

  7. immunostaning for GAP-43 was relatively similar in ganglionic versus aganglionic colon.

  8. Impaired regeneration of intra-epidermal C fibers in the early stages of type 2 diabetes mellitus, as indicated by GAP-43 expression, might be a marker of incipient diabetic neuropathy.

  9. The results of this study supported to the hypothesis of multiple rare mutations in schizophrenia, and it provides genetic clues that indicate the involvement of GAP-43 in this disorder.

  10. Through MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) pathway, S1P (show MBTPS1 Proteins) stimulates GAP43 transcription with increased binding of C/EBPbeta (show CEBPB Proteins) to the 5'-promoter

Mouse (Murine) Growth Associated Protein 43 (GAP43) interaction partners

  1. The GASP (show GPRASP1 Proteins)-43 is involves in the orientation of cell division by interacting with Galphai.

  2. Trimethyltin decreased synaptophysin (show SYP Proteins) but not GAP-43 expression in the mouse hippocampus.

  3. Antiretroviral drugs may recruit the HuD (show ELAVL4 Proteins)-GAP43 pathway, potentially contributing to a response to the antiretroviral neuronal toxicity.

  4. KSRP (show KHSRP Proteins) modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

  5. these findings suggest that GAP-43 is dynamically involved in early postnatal and adult hippocampal neurogenesis and synaptic connectivity, possibly contributing to the GAP-43+/- behavioral phenotype.

  6. In this review, GAP-43 in vivo knockdown in olivary neurons leads to the atrophy of their climbing fibers and a reduction in the ability to sprout toward surrounding denervated Purkinje cells.

  7. GAP-43 is required to sustain synaptic stability and promote the initiation of axonal regrowth

  8. In vitro results indicated that GAP43 is indeed expressed in both myoblasts and differentiating myotubes, and its cellular localization changes dramatically during maturation.

  9. Initial emergence of hollows in the somatosensory cortex is no different between GAP43 heterozygous mice and nonheterozygous littermate controls; however, the emergence of sides and septa (show SEPT2 Proteins) is delayed by 2 days.

  10. This study demonistrated that neuronal responses to netrin-1 (show NTN1 Proteins) have been directly demonstrated to require GAP-43.

Zebrafish Growth Associated Protein 43 (GAP43) interaction partners

  1. these results and GAP43 structural features, support an involvement of the protein in the dynamic intracellular Ca2 (show CA2 Proteins)+ homeostasis, a common conserved role among the different species.

  2. The results implicate the GAP43 pathway as part of an F-actin based mechanism that both stabilizes new synapses and initiates new branches near effective synapses.

  3. The present data strongly suggest that phospho-GAP43 plays an active role in both the early and late stages of optic nerve regeneration in fish.

Cow (Bovine) Growth Associated Protein 43 (GAP43) interaction partners

  1. Both the synthetic N-terminal peptide GAP-43(1-40) and the brain-derived fragment GAP-43-3 preserved the ability to oligomerize under the action of acidic phospholipids and SDS (show SDS Proteins).

  2. These results indicated the interaction of GAP-43 and Galpha(o (show GNAO1 Proteins)) could accelerate conversion of depalmitoylated Galpha(o (show GNAO1 Proteins)) but not palmitoylated Galpha(o (show GNAO1 Proteins)) from oligomers to monomers, so as to increase the GTPgammaS binding activity of Galpha(o (show GNAO1 Proteins)).

GAP43 Protein Profile

Protein Summary

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with GAP43

  • growth associated protein 43 (LOC733695)
  • growth associated protein 43 (Gap43)
  • growth associated protein 43 (GAP43)
  • growth associated protein 43 (gap43)
  • growth associated protein 43 (gap43-a)
  • growth associated protein 43 (LOC100345603)
  • growth associated protein 43 (gap43-b)
  • b-50 protein
  • Basp2 protein
  • cb310 protein
  • gap protein
  • gap-43 protein
  • gap43 protein
  • gap43a protein
  • gap43b protein
  • pp46 protein

Protein level used designations for GAP43

growth associated protein 43 , axonal membrane protein GAP-43 , brain abundant, membrane attached signal protein 2 , growth accentuating protein 43 , growth-associated protein 43 , neuromodulin , protein F1 , calmodulin-binding protein P-57 , nerve growth-related peptide GAP43 , neural phosphoprotein B-50 , neuron growth-associated protein 43 , B-50 , growth associated protein 43 a , growth associated protein 43 b

GENE ID SPECIES
733695 Sus scrofa
29423 Rattus norvegicus
427955 Gallus gallus
2596 Homo sapiens
14432 Mus musculus
493873 Felis catus
30608 Danio rerio
380030 Xenopus laevis
478572 Canis lupus familiaris
281777 Bos taurus
100345603 Oryctolagus cuniculus
100623423 Sus scrofa
100860764 Capra hircus
101103773 Ovis aries
379492 Xenopus laevis
100174106 Pongo abelii
460599 Pan troglodytes
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