GAP43 Protein (His tag)
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- Target See all GAP43 Proteins
- GAP43 (Growth Associated Protein 43 (GAP43))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GAP43 protein is labelled with His tag.
- Purpose
- Recombinant Human GAP43/Neuromodulin Protein (His Tag)
- Sequence
- Met 1-Ala 238
- Characteristics
- A DNA sequence encoding the human GAP43 (P17677) (Met 1-Ala 238) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 96 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GAP43 Protein
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Growth Associated Protein 43 (GAP43) (AA 1-238) protein (His-IF2DI Tag)
GAP43 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Growth Associated Protein 43 (GAP43) (AA 1-238) protein (GST tag)GAP43 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Associated Protein 43 (GAP43) (AA 1-238) protein (Strep Tag)Crystallography grade GAP43 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Growth Associated Protein 43 (GAP43) (AA 1-227) protein (Strep Tag)Crystallography grade GAP43 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Growth Associated Protein 43 (GAP43) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)GAP43 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- GAP43 (Growth Associated Protein 43 (GAP43))
- Alternative Name
- GAP43/Neuromodulin (GAP43 Products)
- Synonyms
- B-50 Protein, PP46 Protein, Basp2 Protein, GAP-43 Protein, b-50 Protein, gap-43 Protein, gap43b Protein, pp46 Protein, cb310 Protein, gap Protein, gap43 Protein, gap43a Protein, growth associated protein 43 Protein, growth associated protein 43 L homeolog Protein, growth associated protein 43 S homeolog Protein, GAP43 Protein, Gap43 Protein, gap43.L Protein, gap43 Protein, gap43.S Protein
- Background
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Background: Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 and GAP43, is a cell membrane protein which belongs to the neuromodulin family. Neuromodulin / GAP43 contains one IQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of neurons. The sudden infant death syndrome (SIDS) is the main cause of postneonatal infant death and its cause is still unknown. Neuromodulin / GAP43 is a marker of synaptic plasticity and is critical for normal development of the serotonergic innervation. Neuromodulin / GAP43 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration. CAP23 and GAP43 are functionally related intrinsic determinants of anatomical plasticity. These proteins function by locally promoting subplasmalemmal actin cytoskeleton accumulation.
Synonym: B-50;PP46
- Molecular Weight
- 26.2 kDa
- UniProt
- P17677
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