anti-Growth Differentiation Factor 5 (GDF5) Antibodies

The protein encoded by GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF5 Kits (59) and GDF5 Proteins (44) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF5 8200 P43026
GDF5 14563 P43027
GDF5 252835  
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Top anti-GDF5 Antibodies at antibodies-online.com

Showing 10 out of 141 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Mouse Target Name: GDF5 Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml WB Suggested Anti-GDF5 Antibody Titration: 1.0 ug/ml Positive Control: Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-GDF5 N-term Pab (ABIN388820) is used in Western blot to detect GDF5 in A549 cell lysate. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GDF5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue reacted with BMP14 / GDF5 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of BMP14 / GDF5 Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the GDF5 antibody detected the GDF5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB GDF5 Antibody (C-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GDF5 antibody detected the GDF5 protein (arrow). GDF5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF5 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632] - A: NIH-3T3 B: JC. Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632] - A: 293T B: A431 C: H1299. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDF-5/BMP-14 Antibody [NBP1-88575] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Western Blot: GDF-5/BMP-14 Antibody [NBP1-88575] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated Func, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDF5 Antibody [NBP2-16631] - Immunohistochemical analysis of paraffin-embedded Colon CA, using antibody at 1:250 dilution. Western Blot: GDF5 Antibody [NBP2-16631] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

GDF5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GDF5 Antibodies

  1. Human Polyclonal GDF5 Primary Antibody for IHC (p), WB - ABIN388820 : Liu, Lin, Sytwu, Chang: GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes. in Experimental and molecular pathology 2010 (PubMed)
    Show all 4 Pubmed References

More Antibodies against GDF5 Interaction Partners

Xenopus laevis Growth Differentiation Factor 5 (GDF5) interaction partners

  1. Changes in the expression of downstream regulators of skeletal differentiation, like barx1 (show BARX1 Antibodies) and gdf5, is one mechanism by which head skeletal element number and articulation are altered during evolution.

  2. Results suggest that CDMP1/GDF5 requires cleavage by two distinct proteolytic enzymes.

Human Growth Differentiation Factor 5 (GDF5) interaction partners

  1. miR (show MLXIP Antibodies)-615-3p negatively regulates the osteogenic differentiation of hLF (show EPAS1 Antibodies) cells through post-transcriptionally suppressing osteogenic regulators GDF5 and FOXO1 (show FOXO1 Antibodies).

  2. p38 (show CRK Antibodies), c-jun (show JUN Antibodies), and NFkappaB (show NFKB1 Antibodies) pathways activated during intervertebral disc degeneration by IL-1beta (show IL1B Antibodies) but not GDF-5

  3. GDF5 elicited significant (p < 0.05) changes in the expression of anabolic, catabolic and hypertrophic genes with several consistent effects in healthy donors and in OA patients

  4. GDF5 was up regulated in patients after chronic rhinosinusitis developing osteitis.

  5. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  6. The purpose of this study is to investigate the immunohistochemical expression of cytokeratin 18 (CK18 (show KRT18 Antibodies)) and the reactivity to GDF5 (CDMP-1), called the morphogenetic protein-1, cartilage-derived, in lingual squamous cell carcinoma.

  7. homozygous sequence variants in the GDF5 gene underlie acromesomelic dysplasia type-grebe in consanguineous families

  8. The prevention of IL-1Beta (show IL1B Antibodies)-induced nucleus pulposus extracellular matrix degeneration by miR-7 (show LILRB1 Antibodies) silencing was attenuated by GDF5 siRNA.

  9. Mutations in three genes (GDF5, NPR2 (show NPRL2 Antibodies), BMPR1B (show BMPR1B Antibodies)) have been reported to cause different forms of acromesomelic dysplasia

  10. we demonstrate that the transforming growth factor-beta1 and the growth differentiation factor 5 synergistically drive the nucleopulpogenic differentiation process. The commitment of the hASCs was robust and highly specific as attested by the expression of NP-related genes characteristic of young healthy human NP cells

Mouse (Murine) Growth Differentiation Factor 5 (GDF5) interaction partners

  1. spatiotemporal dynamics of Gdf5 expression may instruct lineage divergence.

  2. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  3. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2 (show BMP2 Antibodies)-induced Smad1 (show SMAD1 Antibodies)-Smad5 (show SMAD5 Antibodies)-Smad8 (show SMAD9 Antibodies) phosphorylation.

  4. Combined, these data suggest a possible pathway linking GDF5, ERG (show ERG Antibodies) and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  5. Growth differentiation factor 5 is a novel target-derived factor that promotes sympathetic axon growth and branching and makes a distinctive regional contribution to the establishment of sympathetic innervation.

  6. Dach2 (show DACH2 Antibodies) and Hdac9 (show HDAC9 Antibodies) mediate the effects of muscle activity on muscle reinnervation; Myog (show MYOG Antibodies) and Gdf5 appear to stimulate muscle reinnervation through parallel pathways

  7. Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.

  8. Clonal expansion of Gdf5 progenitors contributes to linear growth of the enthesis.

  9. GDF5 might play a critical role in 3T3-L1 preadipocyte differentiation

  10. These results suggest that PI3K/Akt (show AKT1 Antibodies) signals play a role in the GDF5-mediated brown adipogenesis through a mechanism related to activation of the Smad (show SMAD1 Antibodies) pathway.

Cow (Bovine) Growth Differentiation Factor 5 (GDF5) interaction partners

  1. These results suggest that the SNP of the GDF5 gene could be a very useful genetic marker for body measurement traits in the bovine reproduction and breeding.

GDF5 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

Gene names and symbols associated with GDF5

  • growth differentiation factor 5 (gdf5) antibody
  • growth differentiation factor 5 (GDF5) antibody
  • growth differentiation factor 5 (Gdf5) antibody
  • BDA1C antibody
  • BMP14 antibody
  • bp antibody
  • brp antibody
  • Cdmp-1 antibody
  • Cdmp1 antibody
  • gdf antibody
  • gdf-5 antibody
  • GDF5 antibody
  • LAP4 antibody
  • OS5 antibody
  • SYM1B antibody
  • SYNS2 antibody

Protein level used designations for GDF5

growth factor GDF5 , growth differentiation factor 5 , growth/differentiation factor 5-like , CDMP-1 , GDF-5 , cartilage-derived morphogenetic protein-1 , growth/differentiation factor 5 , radotermin , brachypodism , cartilage-derived morphogenetic protein 1 , growth differentiation factor 5 preproprotein , growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)

GENE ID SPECIES
446295 Xenopus laevis
100137480 Papio anubis
100393400 Callithrix jacchus
8200 Homo sapiens
14563 Mus musculus
252835 Rattus norvegicus
100328897 Oryctolagus cuniculus
100723808 Cavia porcellus
100520988 Sus scrofa
485850 Canis lupus familiaris
539559 Bos taurus
374249 Gallus gallus
101116499 Ovis aries
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