anti-Growth Factor, Augmenter of Liver Regeneration (GFER) Antibodies

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. Additionally we are shipping GFER Kits (18) and GFER Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GFER 2671 P55789
GFER 27100 Q63042
GFER 11692 P56213
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Top anti-GFER Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Hepatopoietin Antibody (Center) in HepG2 cell line lysates (35ug/lane). This demonstrates the GFER antibody detected the GFER protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of HepG2 cells using Hepatopoietin Antibody (C-term) Cat.-No AP51820PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of Hepatopoietin Antibody (C-term) in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the GFER antibody detected the GFER protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated FACS, WB GFER Antibody (C-term) (ABIN655619) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the GFER antibody detected the GFER protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB GFER Antibody (Center) (ABIN655148) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the GFER antibody detected the GFER protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Western Blot (WB) analysis of HBE cells using ALR Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GFER staining in human prostate formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of GFER expression in MCF7 (A), A375 (B), mouse liver (C), mouse testis (D), rat brain (E) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

GFER Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GFER Antibodies

  1. Human Polyclonal GFER Primary Antibody for EIA, WB - ABIN952716 : Dong, Sun, Jiang, Shao, Hu, Jiang, Wang, An: Epidermal growth factor down-regulates the expression of human hepatic stimulator substance via CCAAT/enhancer-binding protein β in HepG2 cells. in The Biochemical journal 2010 (PubMed)
    Show all 3 references for 952716

  2. Human Polyclonal GFER Primary Antibody for EIA, FACS - ABIN952717 : Li, Zhang, An: The conserved CXXC motif of hepatic stimulator substance is essential for its role in mitochondrial protection in H2O2-induced cell apoptosis. in FEBS letters 2010 (PubMed)
    Show all 2 references for 952717

More Antibodies against GFER Interaction Partners

Human Growth Factor, Augmenter of Liver Regeneration (GFER) interaction partners

  1. Our results show that MARK4 (show MARK4 Antibodies) acts as a negative regulator of the Hippo kinase cassette to promote YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activity and that loss of MARK4 (show MARK4 Antibodies) restrains the tumorigenic properties of breast cancer cells.

  2. ALR, dependent on its localization, changes the acute-phase response (APR (show LRP1 Antibodies)) at least in part, by modifying STAT3 (show STAT3 Antibodies) activation; dual signaling of ALR suggests that ALR is pivotal for the regulation of APR (show LRP1 Antibodies), a crucial event in liver injury and regeneration

  3. the mechanistic regulation and linkage of the ROR1 (show ROR1 Antibodies)-HER3 (show ERBB3 Antibodies) and Hippo-YAP (show YAP1 Antibodies) pathway in a cancer-specific context

  4. S100A7 (show S100A7 Antibodies) induction by the Hippo-YAP (show YAP1 Antibodies) pathway in cervical and glossopharyngeal squamous cell carcinoma has been described.

  5. FAT1 (show FAT1 Antibodies) protein acts upstream of Hippo signalling through TAZ (show TAZ Antibodies) protein to regulate neuronal differentiation.

  6. ALR protects cells from apoptosis partly through increased autophagy in HepG2 cells.

  7. Knockdown of GFER exerts anti-inflammatory actions via suppression of the mitogen-activated protein kinase (show MAPK1 Antibodies) signaling pathway

  8. ALR plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells.

  9. Data show that the over-expression of 23 kDa augmenter of liver regeneration (ALR) in hepatic cell line LO2 cells promoted the cell proliferation and enhanced cell resistance to hydrogen peroxide.

  10. Upregulation of miR (show MLXIP Antibodies)-130b enhances stem cell-like phenotype in glioblastoma by inactivating the Hippo signaling pathway.

Mouse (Murine) Growth Factor, Augmenter of Liver Regeneration (GFER) interaction partners

  1. The exogenous expression of hepatic stimulator substance (HSS (show PANK2 Antibodies) was renamed augmenter of liver regeneration ALR) protected the liver from steatosis in mice with nonalcoholic steatohepatitis.

  2. this study shows that ALR can weaken ConA-induced hepatitis

  3. ALR is apparently required to ensure appropriate liver regeneration following PH in mice, and deletion of the ALR gene may delay liver regeneration in part due to impaired mitochondrial biogenesis.

  4. ALR can protect mice against acute liver injury by up-regulating the expression of regulatory T cells.

  5. From weeks 2-4 after birth, levels of steatosis and apoptosis decreased in ALR-L-KO mice, and numbers of ALR-expressing cells increased, along with ATP level

  6. As a mechanism, we suggest a direct protective effect of ALR on apoptotic and necrotic death of hepatocytes and an attenuation of inflammatory cell influx into the postischemic tissue.

  7. ALR may serve as a potential diagnostic marker of hepatocellular stress and/or acute inflammatory conditions.

  8. Growth factor erv1-like (Gfer) inhibits the COP9 (show COPS8 Antibodies) signalosome subunit jun activation-domain binding protein 1 (Jab1 (show COPS5 Antibodies))-mediated degradation of the cyclin-dependent kinase inhibitor p27(kip1 (show CDKN1B Antibodies)) to restrict proliferation of hematopoietic stem cells.

  9. Gfer plays an essential pro-survival role in the maintenance of murine embryonic stem cell pluripotency by preserving the structural and functional integrity of their mitochondria, through modulation of the key mitochondrial fission factor (show MFF Antibodies) Drp1 (show CRMP1 Antibodies).

  10. Growth factor erv1-like modulates Drp1 (show CRMP1 Antibodies) to preserve mitochondrial dynamics and function in mouse embryonic stem cells

GFER Antigen Profile

Protein Summary

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.

Gene names and symbols associated with GFER

  • growth factor, augmenter of liver regeneration (GFER) antibody
  • growth factor, augmenter of liver regeneration (gfer) antibody
  • growth factor, augmenter of liver regeneration (Gfer) antibody
  • growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) (Gfer) antibody
  • Alr antibody
  • ERV1 antibody
  • HERV1 antibody
  • HPO antibody
  • HPO1 antibody
  • HPO2 antibody
  • HSS antibody

Protein level used designations for GFER

growth factor, augmenter of liver regeneration , growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) , FAD-linked sulfhydryl oxidase ALR , ERV1 homolog , erv1-like growth factor , hepatic regenerative stimulation substance , hepatopoietin protein , augmenter of liver regeneration , growth factor, erv1 homolog , growth factor, erv1-like (augmenter of liver regeneration)

GENE ID SPECIES
479885 Canis lupus familiaris
618423 Bos taurus
694203 Macaca mulatta
733269 Xenopus laevis
750034 Pan troglodytes
2671 Homo sapiens
27100 Rattus norvegicus
11692 Mus musculus
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