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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Antibodies

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. Additionally we are shipping GNAI1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNAI1 14677 B2RSH2
GNAI1 2770 P63096
GNAI1 25686 P10824
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Top anti-GNAI1 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-GNAI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human brain Sample Type: Nthy-ori cell lysate (50ug)Primary Dilution: 1:1000Secondary Antibody: anti-rabbit HRPSecondary Dilution: 1:2000Image Submitted By: Anonymous 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (65.05 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Rat Mouse Un-conjugated IHC (p), WB Human Pancreas (formalin-fixed, paraffin-embedded) stained with GNAI1 antibody ABIN337268 at 1:50 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of GNAI1 expression in Jurkat (A), SHSY5Y (B), SP2/0 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Fruit Fly Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to GNAI1 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged GNAI1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Rat Rabbit Un-conjugated ICC, IP, WB   50 μL Log in to see 8 to 10 Days
$771.83
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Cow Mouse Un-conjugated IHC, WB 0.05 mL Log in to see 2 to 3 Days
$481.25
Details

GNAI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,
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Human ,
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Rat (Rattus) ,
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Top referenced anti-GNAI1 Antibodies

  1. Chicken Polyclonal GNAI1 Primary Antibody for WB - ABIN2785808 : Hurst, Henkel, Brown, Hooks: Endogenous RGS proteins attenuate Galpha(i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells. in Cellular signalling 2008 (PubMed)

  2. Human Polyclonal GNAI1 Primary Antibody for ELISA, WB - ABIN561067 : Sasaki, Yamasaki, Omotuyi, Mishina, Ueda: Age-dependent dystonia in striatal G?7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole. in Journal of neurochemistry 2013 (PubMed)

More Antibodies against GNAI1 Interaction Partners

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. stimulation of GPR17 (show GPR17 Antibodies) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP Antibodies) expression levels mainly by triggering the Galphai/o signaling pathway.

  2. Gnai1 missense mutation is responsible of hyperpigmentation in mouse model.

  3. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

  4. Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.

  5. By using mice deficient in individual Galphai/o G-protein subunits, authors demonstrate that Galphai1 and Galphai3 are the critical in vivo targets of ADP-ribosylation underlying vasoactive amine sensitization elicited by pertussis toxin exposure.

  6. leucine can directly facilitate insulin (show INS Antibodies) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.

  8. Mice with mutations of Gnai1 or Gnai2 (show GNAI2 Antibodies) have neither fusions of ribs nor lumbar vertebrae, but loss of both Gnai3 (show GNAI3 Antibodies) and one of the other two genes increases the number and severity of rib fusions without affecting the lumbar fusions.

  9. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (show GNAO1 Antibodies)) upon activation of mGluR6 (show GRM6 Antibodies) closes the TRPM1 (show TRPM1 Antibodies) channel, perhaps via a direct interaction.

  10. RGS14 (show RGS16 Antibodies) can form complexes with GPCRs in cells that are dependent on Galpha (show SUCLG1 Antibodies)(i/o) and these RGS14 (show RGS16 Antibodies).Galpha (show SUCLG1 Antibodies)(i1).GPCR (show GPBAR1 Antibodies) complexes may be substrates for other signaling partners such as Ric-8A (show RIC8A Antibodies)

Human Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. Data indicate that hydroxyurea (HU) induces SAR1 (show IQGAP1 Antibodies) protein expression, which in turn activates gamma-globin (show HBG1 Antibodies) expression, predominantly through the Gialpha/JNK (show MAPK8 Antibodies)/Jun (show JUN Antibodies) pathway.

  2. Gi alpha subunit (show POLG Antibodies) was found to be a key modulator of GABAB-receptors signaling in analgesia.

  3. AC5, by binding active Galphai1, interferes with G-protein deactivation and reassembly and thereby might sensitize its own regulation.

  4. Data indicate that focal adhesion kinase (FAK) activation and cell migration require Src, Gi/Go, COX-2 and LOXs activities.

  5. resistin (show RETN Antibodies) contributes to the pro-inflammatory state of SMC (show DYM Antibodies) by the up-regulation of CX3CL1 (show CX3CL1 Antibodies) and CX3CR1 (show CX3CR1 Antibodies) expression via a mechanism involving NF-kB, AP-1 (show FOSB Antibodies), and STAT1 (show STAT1 Antibodies)/3 transcription factors, (2) resistin (show RETN Antibodies) employs TLR4 (show TLR4 Antibodies) and Gi-protein signaling.

  6. leucine can directly facilitate insulin (show INS Antibodies) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Data suggest that chemokine (show CCL1 Antibodies) binding to CCX-CKR (show CCRL1 Antibodies) (a) recruits Gi proteins and beta-arrestin (beta-arr (show SAG Antibodies)) with high affinity.

  8. This study support a role for RGS (show PITX2 Antibodies) proteins as negative regulators of opioid supraspinal antinociception and also reveal a potential novel function of RGS (show PITX2 Antibodies) proteins as positive regulators of opioid spinal antinociceptive pathways.

  9. Galpha(o (show GNAO1 Antibodies)) protein contributes to maximally efficient mu-opioid receptor (show OPRM1 Antibodies) signaling and antinociception in Galpha(o (show GNAO1 Antibodies)) null transgenic mice.

  10. CXCL12 (show CXCL12 Antibodies) signaling via CXCR7 (show CXCR7 Antibodies) is Gialpha independent.

GNAI1 Antigen Profile

Protein Summary

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GNAI1

  • guanine nucleotide binding protein (G protein), alpha inhibiting 1 (Gnai1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1-b) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (Gnai1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1) antibody
  • AU046200 antibody
  • BPGTPB antibody
  • Gi antibody
  • Gialpha1 antibody
  • Gnai-1 antibody
  • gnai1 antibody
  • zgc:63957 antibody

Protein level used designations for GNAI1

adenylate cyclase-inhibiting G alpha protein , guanine nucleotide binding protein, alpha inhibiting 1 , guanine nucleotide-binding protein G(i) subunit alpha-1 , Gi1 protein alpha-subunit , alpha-subunit of G-protein, type G-alpha-i-1 , guanine nucleotide-binding protein G(i), alpha-1 subunit , Gi1 protein alpha subunit , Gi-alpha-1 protein , guanine nucleotide binding protein (G protein), alpha inhibiting 1 , Galpha i1a

GENE ID SPECIES
14677 Mus musculus
100135528 Cavia porcellus
399463 Xenopus laevis
396368 Gallus gallus
2770 Homo sapiens
397505 Sus scrofa
281790 Bos taurus
25686 Rattus norvegicus
393946 Danio rerio
Selected quality suppliers for anti-GNAI1 (GNAI1) Antibodies
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