GNAI1 antibody (AA 21-120)

Catalog No. ABIN1715011

This Rabbit Polyclonal antibody specifically detects GNAI1 in ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for GNAI1 antibody (AA 21-120) (ABIN1715011)

Target: GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAI1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-GNAI1 Antibody

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein alpha inhibitor 1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNAI1

Target: GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))

Alternative Name: G protein alpha inhibitor 1

Background:

Synonyms: Adenylate cyclase inhibiting G alpha protein, Adenylate cyclase inhibitory protein, Adenylate cyclase-inhibiting G alpha protein, G protein alpha inhibiting 1, G protein alpha inhibiting activity polypeptide 1, Gi, Gi inhibitory G protein, Gi1 protein alpha subunit, GNAI 1, GNAI1, GNAI1_HUMAN, Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 1, Guanine nucleotide binding protein alpha inhibiting activity polypeptide 1, Guanine nucleotide binding protein Gi alpha 1 subunit, Guanine nucleotide-binding protein Gi subunit alpha-1, OTTHUMP00000161319, OTTHUMP00000208047.

Background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.

Gene ID: 2770

Pathways: G-protein mediated Events