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anti-Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) Antibodies

GUCA2B encodes a member of the guanylin family, and is expressed in the stomach and intestine. Additionally we are shipping GUCA2B Kits (15) and GUCA2B Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUCA2B 64055 P70668
GUCA2B 14916 O09051
GUCA2B 2981 Q16661
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Top anti-GUCA2B Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GUCA2B Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the GUCA2B antibody detected the GUCA2B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, RIA, WB Immunohistochemistry of Uroguanylin staining in LR White resin section of Human gastric mucosa. The section was incubated with AP23439SU (1/800) overnight at 4°C and detected using Biotin conjugated secondary antibody. The section was counterstained with Methylene-azure blue. This antibody detects Uroguanylin in D-cells of Gastric mucosa (arrows). Mägert HJ et al. . Regul pept73:165-176. 0.1 mL Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated IHC (fro), WB Immunohistochemistry of Uroguanylin staining in Cyryosection of Human Prostate. The section was Fixed in Acetone, incubated with AP23440SU (1/2000) 72h at 4°C and detected using Biotin-Streptavidin technique. 3,3'-di-aminobenzidine was used as the Chromogen. This antibody detects Uroguanylin in luminal part of grandular epithelial cells and in cell protrusions (arrows). Maake C et al. . Histochem Cell Biol 119:69-76. Western nlot analysis of AP23440SU specificity. Prostatic fluid from healthy donors was separated by SDS-PAGE und reducing conditions and immunoblotted with AP23440SU (1/20,000). Lane 1: AP23440SU detects Uroguanylin as a band migrating at 12-13 kDa. Lane 2: Negative Control incubated with non-immune Serum. Arrow: Aprotinin, 9 kDa. Double Arrow: Lysozyme, 16.8 kDa. Maake C et al. . Histochem Cell Biol 119:69-76. 0.1 mL Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated WB GUCA2B Antibody (C-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GUCA2B antibody detected the GUCA2B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Mouse Rabbit Un-conjugated WB   100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB Western Blot analysis of GUCA2B expression in transfected 293T cell line by GUCA2B MaxPab polyclonal antibody.Lane 1: GUCA2B transfected lysate(12.10 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details

GUCA2B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)

Mouse (Murine) ,


, ,
Human ,
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Top referenced anti-GUCA2B Antibodies

  1. Human Polyclonal GUCA2B Primary Antibody for EIA, WB - ABIN952662 : Yoshikawa, Nakayama, Saito, Hui, Morita, Sato, Takahashi, Tamura, Sato, Aoi, Doba, Hinohara, Soma, Usami: Haplotype-based case-control study of the association between the guanylate cyclase activator 2B (GUCA2B, Uroguanylin) gene and essential hypertension. in Hypertension research : official journal of the Japanese Society of Hypertension 2007 (PubMed)
    Show all 5 references for ABIN952662

  2. Human Polyclonal GUCA2B Primary Antibody for EIA, IHC (fro) - ABIN615644 : Hess, Kuhn, Schulz-Knappe, Raida, Fuchs, Klodt, Adermann, Kaever, Cetin, Forssmann: GCAP-II: isolation and characterization of the circulating form of human uroguanylin. in FEBS letters 1995 (PubMed)
    Show all 2 references for ABIN615644

  3. Human Polyclonal GUCA2B Primary Antibody for IHC (fro), WB - ABIN615646 : Maake, Auf der Maur, Jovanovic, Reinecke, Hauri, John: Occurrence and localization of uroguanylin in the aging human prostate. in Histochemistry and cell biology 2003 (PubMed)

More Antibodies against GUCA2B Interaction Partners

Mouse (Murine) Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) interaction partners

  1. UGN exerts its inhibitory activity on the prendrin gene promoter likely via heat shock factor 1 action at a defined heat shock element site.

  2. findings establish a role for uroguanylin in an enteric-renal communication axis as well as a fundamental principle of this axis in the maintenance of salt homeostasis in vivo

  3. act on the mouse kidney, in part, through a cGMP-dependent, GC-C (show GUCY2C Antibodies)-independent mechanism, causing significant natriuresis by renal tubular processes.

  4. existence of two signaling pathways for guanylin (show GUCA2A Antibodies) peptides in principal cells of mouse cortical collecting duct of kidney

  5. Role for uroguanylin in fluid homeostasis and as an integral component of a signaling mechanism that mediates changes in Na excretion in response to an enteral salt loading.

Human Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) interaction partners

  1. Uroguanylin concentrations are increased in patients with chronic renal failure, nephrotic syndrome, or those on dialysis.

GUCA2B Antigen Profile

Protein Summary

This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.

Gene names and symbols associated with GUCA2B

  • guanylate cyclase activator 2B (uroguanylin) (GUCA2B) antibody
  • guanylate cyclase activator 2B (Guca2b) antibody
  • guanylate cyclase activator 2b (retina) (Guca2b) antibody
  • AV066530 antibody
  • GCAP-II antibody
  • Gcap2 antibody
  • GUCA2B antibody
  • UGN antibody

Protein level used designations for GUCA2B

guanylate cyclase activator 2B (uroguanylin) , guanylate cyclase activator 2B , guanylate cyclase activator 2b (retina) , uroguanylin , granule cell antiserum positive 2 , guanylyl cyclase activating peptide II

GENE ID SPECIES
469301 Pan troglodytes
699525 Macaca mulatta
515664 Bos taurus
64055 Rattus norvegicus
14916 Mus musculus
100135535 Cavia porcellus
2981 Homo sapiens
100301561 Sus scrofa
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