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anti-HNF1 Homeobox B (HNF1B) Antibodies

HNF1B encodes a member of the homeodomain-containing superfamily of transcription factors. Additionally we are shipping HNF1 Homeobox B Kits (31) and HNF1 Homeobox B Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNF1B 6928 P35680
HNF1B 21410 P27889
HNF1B 25640 P23899
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Top anti-HNF1 Homeobox B Antibodies at

Showing 10 out of 123 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-HNF1B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
Dog Rabbit Un-conjugated WB WB Suggested Anti-HNF1B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate Host: Rabbit  Target Name: HNF1B  Sample Tissue: Human Fetal Muscle  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN334505 (0.1 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
Cow Goat Un-conjugated EIA, IF, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HNF1 beta / TCF2 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the HNF1B antibody detected the HNF1B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Dog Mouse Un-conjugated IF, WB Western blot analysis of HNF-1beta on a rat kidney lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti- HNF-1beta antibody. Immunofluorescence staining of normal rat kidney. 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-HNF1B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: ACHN cell lysate WB Suggested Anti-HNF1B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: ACHN cell lysate  HNF1B is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB HNF1B Antibody (C-term) (ABIN655066) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the HNF1B antibody detected the HNF1B protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days

HNF1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HNF1 Homeobox B Antibodies

  1. Dog (Canine) Monoclonal HNF1B Primary Antibody for IF, WB - ABIN968855 : De Simone, De Magistris, Lazzaro, Gerstner, Monaci, Nicosia, Cortese: LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia. in The EMBO journal 1991 (PubMed)
    Show all 3 references for ABIN968855

  2. Human Polyclonal HNF1B Primary Antibody for ELISA, WB - ABIN334505 : Terasawa, Toyota, Sagae, Ogi, Suzuki, Sonoda, Akino, Maruyama, Nishikawa, Imai, Shinomura, Saito, Tokino: Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines. in British journal of cancer 2006 (PubMed)
    Show all 2 references for ABIN334505

  3. Human Polyclonal HNF1B Primary Antibody for WB - ABIN871758 : Lindner, Njolstad, Horikawa, Bostad, Bell, Sovik: A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta. in Human molecular genetics 1999 (PubMed)
    Show all 2 references for ABIN871758

  4. Chicken Polyclonal HNF1B Primary Antibody for WB - ABIN2779562 : Wu, Bohn, Ryffel: The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations. in European journal of biochemistry / FEBS 2004 (PubMed)

  5. Human Polyclonal HNF1B Primary Antibody for EIA, WB - ABIN952765 : Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010 (PubMed)

  6. Cow (Bovine) Polyclonal HNF1B Primary Antibody for EIA, IF - ABIN375249 : Arenas, Hervias, Uriz, Joplin, Prieto, Medina: Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. in The Journal of clinical investigation 2008 (PubMed)

  7. Dog (Canine) Polyclonal HNF1B Primary Antibody for WB - ABIN2777700 : Hakonarson, Qu, Bradfield, Marchand, Kim, Glessner, Grabs, Casalunovo, Taback, Frackelton, Eckert, Annaiah, Lawson, Otieno, Santa, Shaner, Smith, Onyiah, Skraban, Chiavacci, Robinson, Stanley, Kirsch et al.: A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. ... in Diabetes 2008 (PubMed)

More Antibodies against HNF1 Homeobox B Interaction Partners

Human HNF1 Homeobox B (HNF1B) interaction partners

  1. HNF-1B-positive malignant cells could be bipotential cells and give rise to both hepatocytic and cholangiocytic lineages during tumorigenesis.

  2. Early-stage ovarian clear cell carcinoma tended to have high levels of HNF-1beta immunoreactivity. Low-level HNF-1beta expression was observed in patients with recurrence and high-level HNF-1beta was associated with good prognosis.

  3. rs4430796 polymorphism of HNF1B gene influences independently the prognosis of EC patients with a potential effect on tumor chemo-sensitivity.

  4. Combining HNF-1beta and napsin A (show NAPSA Antibodies) may distinguish clear cell carcinoma from high-grade serous carcinoma, endometrioid adenocarcinoma and metastatic Krukenberg tumors.

  5. Meta-analysis of the association between the HNF1B rs4430796 (A>G) polymorphism and risk of prostate cancer based on case-control studies.

  6. HNF1B score was discriminatory for HNF1B mutations in a large cohort of individuals tested in a single UK centre

  7. In cervical carcinoma, expression of HNF-1beta is mostly restricted to adenocarcinomas and can be used as an auxiliary adenocarcinoma marker in the differential diagnosis of poorly differentiated cervical carcinomas.

  8. Our findings provide evidence for a single signal associated with endometrial cancer risk at the HNF1B locus, and that risk is likely mediated via altered HNF1B gene expression.

  9. Results indicated that the downregulation of HNF1B may contribute to drug resistance in ovarian cancer, through various pathways.

  10. Studied upstream and downstream regulatory factors of HNF-1beta in ovarian clear cell carcinomas.

Xenopus laevis HNF1 Homeobox B (HNF1B) interaction partners

  1. Overexpression of two mutant HNF1B derivatives resulted in distinct phenotypes reflected by either a reduction or an enlargement of pronephros size.

  2. nephrogenic transcription factors (osr1 (show OSR1 Antibodies), osr2, hnf1b, lhx1 (show LHX1 Antibodies), pax8 (show PAX8 Antibodies))play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A (show INHBA Antibodies), retinoic acid

  3. CHOP (GADD153 (show DDIT3 Antibodies)) is an inhibitor of Wnt (show WNT2 Antibodies)/TCF (show HNF4A Antibodies) signals

Mouse (Murine) HNF1 Homeobox B (HNF1B) interaction partners

  1. HNF-1beta Regulates MicroRNA-200 Expression through a Long Noncoding RNA

  2. TNFalpha (show TNF Antibodies) regulates uromodulin (show UMOD Antibodies) expression in a homeostatic setting, but the impact of TNFalpha (show TNF Antibodies) on uromodulin (show UMOD Antibodies) during kidney injury is superseded by other factors that could inhibit HNF1beta-mediated expression of uromodulin (show UMOD Antibodies).

  3. Hypoxia induced early up-regulation of Hnf-1beta from 1 to 24 hours, independently of the hypoxia-inducible factor Hif-1alpha (show HIF1A Antibodies).

  4. Zyxin (show ZYX Antibodies) regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1beta.

  5. HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch (show NOTCH1 Antibodies) signalling components and Irx1 (show IRX1 Antibodies)/2.

  6. identification of Hnf1b as a target of miR (show MLXIP Antibodies)-802-dependent silencing; show that short hairpin RNA (shRNA)-mediated reduction of Hnf1b in liver causes glucose intolerance, impairs insulin (show INS Antibodies) signalling and promotes hepatic gluconeogenesis

  7. Hnf1b and Pax2 (show PAX2 Antibodies) operate to control kidney morphogenesis and ureter differentiation.

  8. Overexpression of HNF1beta resulted in accelerated cell proliferation with the protein level up-regulation of plasminogen (show PLG Antibodies) and plasmin (show PLG Antibodies), a converted active form of plasminogen (show PLG Antibodies), which play a pivotal role in liver regeneration inducing hepatocyte proliferation.

  9. Data indicate that HNF1alpha (show HNF1A Antibodies) is a more potent activator of AFM (show AFM Antibodies) promoter than is HNF1beta.

  10. Study identifies new direct target genes of the Hnf1b transcription factors and shows that they play crucial roles in both defining cell fate and controlling terminal functions in the gut (show GUSB Antibodies) epithelium.

Zebrafish HNF1 Homeobox B (HNF1B) interaction partners

  1. Data show that hnf1ba generates a permissive domain for Wnt (show WNT2 Antibodies) signaling activity in the foregut endoderm

  2. Knockdown of pk1a led to decreased expression of vhnf1, a homeodomain gene previously shown to be involved in biliary development and in kidney cyst formation; forced expression of vhnf1 mRNA led to rescue of the pk1a morphant phenotype

  3. Data show that vhnf1 functions in two ways to subdivide the zebrafish caudal (show CAD Antibodies) hindbrain domain (r4-r7) into individual rhombomeres.

  4. Zebrafish tcf2 gene, composed of 9 exons, was mapped to linkage group LG15.

  5. vhnf1 acts largely independently of val to repress the rhombomere 4 'hox (show MSH2 Antibodies) code' posterior to the rhombomere 4-5 boundary

  6. Vhnf1 expression within the posterior neural tube (up to r5) promotes posterior and dorsal fates in the otic vesicle, at the expense of anterior and ventral fates.

  7. investigated the signaling pathways that regulate vhnf1 expression during pancreas development

  8. Data show that zebrafish mutants for Tcf2 fail to specify a single lumen in their gut (show GUSB Antibodies) tube and instead develop multiple lumens, and show that Tcf2 controls single lumen formation by regulating claudin15 and Na+/K+-ATPase (show ATP1A1 Antibodies) expression.

  9. vHNF1 plays crucial role at the earliest steps of liver induction: the acquisition of endoderm competence and the hepatic specification.

  10. It was concluded that hnf1b(hi2169) is hypomorphic to hnf1b(hi1843) and that, while hnf1b is required for r5/r6 gene expression in the hindbrain, r5/r6 gene expression can be experimentally induced independently of hnf1b anterior to the hindbrain.

HNF1 Homeobox B (HNF1B) Antigen Profile

Protein Summary

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-HNF1 Homeobox B (HNF1B) Antibodies

  • HNF1 homeobox B (HNF1B) antibody
  • hepatocyte nuclear factor 1-beta-like (LOC100355480) antibody
  • HNF1 homeobox B (hnf1b) antibody
  • HNF1 homeobox B (Hnf1b) antibody
  • HNF1 homeobox Ba (hnf1ba) antibody
  • transcription factor 2 (hnf1b) antibody
  • AI385728 antibody
  • AI987804 antibody
  • chunp6877 antibody
  • FJHN antibody
  • HNF-1b antibody
  • HNF-1Beta antibody
  • hnf1-beta antibody
  • hnf1b antibody
  • Hnf1beta antibody
  • HNF2 antibody
  • HPC11 antibody
  • LF-B3 antibody
  • lfb3 antibody
  • MODY5 antibody
  • mst antibody
  • Tcf-2 antibody
  • Tcf2 antibody
  • vHNF-1 antibody
  • vHNF1 antibody

Protein level used designations for anti-HNF1 Homeobox B (HNF1B) Antibodies

transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor , HNF1 homeobox B , HNF-1-beta , HNF1 beta A , hepatocyte nuclear factor 1-beta , homeoprotein LFB3 , transcription factor 2, hepatic , FPC-binding protein , FPCB , HNF-1B , TCF-2 , variant hepatic nuclear factor 1 , hepatocyte nuclear factor-1 beta , transcription factor 2 , Transcription factor 2 hepatic , Transcription factor 2 hepatic; LF-B3; variant hepatic nuclear factor , Transcription factor 2, hepatic , Transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor , hepatocyte nuclear factor 1 beta , HNF-1-beta-A , HNF-1B-2 , HNF-1B-A , HNF1 homeobox b , hepatocyte nuclear factor 1-beta-2 , hepatocyte nuclear factor 1-beta-A , hob , xlFB3

468227 Pan troglodytes
100057769 Equus caballus
100355480 Oryctolagus cuniculus
6928 Homo sapiens
398842 Xenopus laevis
427838 Gallus gallus
610402 Canis lupus familiaris
397002 Sus scrofa
21410 Mus musculus
25640 Rattus norvegicus
100734532 Cavia porcellus
503581 Bos taurus
792391 Danio rerio
380377 Xenopus laevis
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