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Hematopoietic Prostaglandin D Synthase Proteins (HPGDS)

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. Additionally we are shipping HPGDS Antibodies (12) and HPGDS Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HPGDS 27306 O60760
HPGDS 54486 Q9JHF7
HPGDS 58962 O35543
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Top HPGDS Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 16 Days
$250.80
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,480.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,482.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
Yeast Human Un-conjugated   100 μg Log in to see 9 to 14 Days
$369.79
Details

HPGDS Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

Top referenced HPGDS Proteins

  1. Human HPGDS Protein expressed in Escherichia coli (E. coli) - ABIN1098288 : Uchida, Urade, Mori, Kohzuma: UV resonance Raman studies on the activation mechanism of human hematopoietic prostaglandin D(2) synthase by a divalent cation, Mg(2+). in Journal of inorganic biochemistry 2010 (PubMed)
    Show all 2 references for ABIN1098288

More Proteins for Hematopoietic Prostaglandin D Synthase (HPGDS) Interaction Partners

Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. The effect of C. molle alkaloid extract on H-PGDS was studied. The alkaloid extract exhibited a 70% inhibition on H-PGDS with an IC50 of 13.7 mug/ml.

  2. the Val187Ile HPGDS isoenzyme common among African Americans is not associated with colorectal cancer risk

  3. COX-1 and H-PGDS were rapidly ubiquitinated and degraded through the ubiquitin-proteasome system in response to the elevation of the intracellular calcium level

  4. In patients with mixed atrophy, testicular mast cell numbers and phenotypes change with respect to the ability to express COX2 and PGDS (show PTGDS Proteins)-H.

  5. New polymorphisms of haematopoietic prostaglandin D synthase (show PTGDS Proteins)

  6. Data suggest that the suppressive effect of hematopoietic prostaglandin D synthase on lung injury could be partly mediated by edema formation and inhibition of genes involved in fibrosis.

  7. X-ray structure of human H-PGDS complexed with an inhibitor, 2-(2'-benzothiazolyl)-5-styryl-3-(4'-phthalhydrazidyl) tetrazolium chloride (BSPT) at 1.9 A resolution in the presence of Mg(2 (show MUC7 Proteins)+).

  8. PU.1 cooperates with MAPK (show MAPK1 Proteins)-activated cJun (show JUN Proteins) to maximally induce L-PGDS (show PTGDS Proteins) expression in macrophages.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (show MMP9 Proteins) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (show MMP9 Proteins) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  2. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  3. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (show SOX9 Proteins).

  4. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  5. hPGD (show HPGD Proteins)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  6. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS Protein Profile

Protein Summary

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (hpgds)
  • hematopoietic prostaglandin D synthase (HPGDS)
  • hematopoietic prostaglandin D synthase (Hpgds)
  • GSTS protein
  • GSTS1-1 protein
  • H-PGDS protein
  • PGD2 protein
  • PGDS protein
  • Ptgds2 protein
  • XlGSTS1 protein

Protein level used designations for HPGDS

prostaglandin D2 synthase, hematopoietic , GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , H-PGDS , glutathione S-transferase , prostaglandin-D synthase , prostaglandin D2 synthase 2, hematopoietic

GENE ID SPECIES
448666 Xenopus (Silurana) tropicalis
27306 Homo sapiens
395863 Gallus gallus
54486 Mus musculus
58962 Rattus norvegicus
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