You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Hemochromatosis (HFE) Antibodies

The protein encoded by HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). Additionally we are shipping HFE Proteins (15) and HFE Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HFE 3077 Q30201
HFE 29199 O35799
HFE 15216 P70387
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-HFE Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HFE Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HFE antibody (Center) in Jurkat cell line lysates (35 µg/lane). HFE (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of HFE antibody (Center) (ABIN390457) in Jurkat cell line lysates (35 µg/lane). HFE (arrow) was detected using the purified polyclonal antibody. HFE Antibody (Center) (ABIN390457) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to HFE on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of HFE expression in transfected 293T cell line by HFE monoclonal antibody (M01), clone 1G12. Lane 1: HFE transfected lysate(40.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ICC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunofluorescence analysis of HepG2 cells using HFE mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HFE Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate WB Suggested Anti-HFE  Antibody Titration: 0.2-1 µg/mL  Positive Control: Hela cell lysate  There is BioGPS gene expression data showing that HFE is expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to HFE on HeLa cell. [antibody concentration 10 ug/ml] HFE monoclonal antibody (M01), clone 1G12. Western Blot analysis of HFE expression in A-431. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ICC, IF, IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

HFE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
,
,
, , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , , ,

Top referenced anti-HFE Antibodies

  1. Human Monoclonal HFE Primary Antibody for IF, WB - ABIN395159 : Lehmann, Schuur, Warden, Hammond, Belbin, Kölsch, Lehmann, Wilcock, Brown, Kehoe, Morris, Barker, Coto, Alvarez, Deloukas, Mateo, Gwilliam, Combarros, Arias-Vásquez, Aulchenko, Ikram, Breteler, van Duijn, Oulhaj, Heun, Cortina-Borja, Morgan, Robson, Smith: Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. in Neurobiology of aging 2011 (PubMed)
    Show all 5 references for ABIN395159

  2. Human Polyclonal HFE Primary Antibody for IHC (p), WB - ABIN390457 : Valenti, Girelli, Valenti, Castagna, Como, Campostrini, Rametta, Dongiovanni, Messa, Fargion: HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients. in Clinical journal of the American Society of Nephrology : CJASN 2009 (PubMed)
    Show all 2 references for ABIN390457

  3. Human Monoclonal HFE Primary Antibody for ICC, ELISA - ABIN969192 : Hosgood, Menashe, He, Chanock, Lan: PTEN identified as important risk factor of chronic obstructive pulmonary disease. in Respiratory medicine 2009 (PubMed)
    Show all 2 references for ABIN969192

  4. Human Polyclonal HFE Primary Antibody for EIA, WB - ABIN453091 : Won, Jeong, Chung, Lee, Hwang, Kim, Lee, Kim, Park, Lee, Kim: Hepatic iron, serum ferritin, HFE mutation, and hepatic fibrosis in chronic hepatitis C. in Intervirology 2009 (PubMed)
    Show all 2 references for ABIN453091

  5. Human Monoclonal HFE Primary Antibody for IF, ELISA - ABIN561252 : Lenarduzzi, Hui, Yue, Ito, Shi, Williams, Bruce, Sakemura-Nakatsugawa, Xu, Schimmer, Liu: Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer. in PLoS ONE 2013 (PubMed)

  6. Cow (Bovine) Polyclonal HFE Primary Antibody for IHC, WB - ABIN2781800 : Gleeson, Evans, Bradley, Jones, Peck, Dube, Rigby, Dalton: HFE genotypes in decompensated alcoholic liver disease: phenotypic expression and comparison with heavy drinking and with normal controls. in The American journal of gastroenterology 2006 (PubMed)

More Antibodies against HFE Interaction Partners

Human Hemochromatosis (HFE) interaction partners

  1. HFE gene expression level of iron deficiency anemia patients was significantly higher than other groups.

  2. The HFE- and non-HFE hemochromatosis syndromes represent the paradigms of genetic iron overload.

  3. results indicate the association between the C282Y/Q283P compound heterozygous genotype in trans and the development of iron overload; this is the second case report on the HFE Q283P mutation in hemochromtosis

  4. study provides evidence that the complex allele HFE-c.[187C>G;340+4T>C] has a role, as genetic predisposition factor, on iron overload in the Sao Miguel population

  5. Its polymorphism does not influence ALS phenotype and survival.

  6. iron dysregulation associated with HFE allelic variants may play an important role in increasing susceptibility to environmental exposures, leading to recurring injury and fibrosis in idiopathic pulmonary fibrosis

  7. this review describes the pertinence of HFE and HFE to mechanisms of iron homeostasis, the origin and fixation of HFE polymorphisms in European and other populations, and the genetic and biochemical basis of HFE hemochromatosis and iron overload. [review]

  8. this analysis provided strong evidence that the HFE H63D polymorphism may play a critical role in the increased aggressiveness of hepatocellular carcinoma and pancreatic cancer.

  9. haplotype analysis of common HFE mutations in the Portuguese population, is reported.

  10. The result support the notion that HFE contributes, at least in part, to the generation of low peripheral blood CD8 (show CD8A Antibodies)+ T lymphocytes in hemochromatosis.

Mouse (Murine) Hemochromatosis (HFE) interaction partners

  1. unlike homozygous Hfe deletion, heterozygous gene deletion disrupted glucose homeostasis but did not affect lipid metabolism or liver injury.

  2. Single Hjv (show HFE2 Antibodies)(-)/(-) and double Hfe(-)/(-)Hjv (show HFE2 Antibodies)(-)/(-) mice exhibit comparable iron overload. Hfe and Hjv (show HFE2 Antibodies) regulate hepcidin (show HAMP Antibodies) via the same pathway.

  3. Results show that HFE requires HJV (show HFE2 Antibodies) to activate downstream signal transduction pathways for hepcidin (show HAMP Antibodies) regulation.

  4. Alterations in cholesterol metabolism associated with expression of H63D-HFE may contribute to the development of AD.

  5. results provide evidence that HFE induces hepcidin (show HAMP Antibodies) expression via the BMP pathway: HFE interacts with ALK3 (show BMPR1A Antibodies) to stabilize ALK3 (show BMPR1A Antibodies) protein and increase ALK3 (show BMPR1A Antibodies) expression at the cell surface.

  6. These results support in vivo studies which suggest that Hfe and Tfr2 (show TFR2 Antibodies) can independently regulate hepcidin (show HAMP Antibodies).

  7. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice.

  8. Hfe-knockout mice did not have higher brain iron levels than wildtype controls.

  9. Hfe(-/-) retinal pigment epithelial cells exhibited slower senescence rate and higher survivin (show BIRC5 Antibodies) expression than wild type cells. Hfe(-/-) cells migrated faster and showed greater glucose uptake and increased expression of GLUTs.

  10. Findings suggest a novel role for Hfe and/or imbalanced iron homeostasis in the regulation of the inflammatory response in the lung and hereditary hemochromatosis.

HFE Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Gene names and symbols associated with anti-Hemochromatosis (HFE) Antibodies

  • hemochromatosis (HFE) antibody
  • hemochromatosis (Hfe) antibody
  • HFE1 antibody
  • HH antibody
  • HLA-H antibody
  • MR2 antibody
  • MVCD7 antibody
  • TFQTL2 antibody

Protein level used designations for anti-Hemochromatosis (HFE) Antibodies

MHC class I-like protein HFE , hereditary hemochromatosis protein , hereditary hemochromatosis protein HLA-H , high Fe , RT1-CAFE , hereditary hemochromatosis protein homolog , hemochromatosis protein

GENE ID SPECIES
3077 Homo sapiens
497622 Bos taurus
29199 Rattus norvegicus
15216 Mus musculus
462489 Pan troglodytes
100688951 Canis lupus familiaris
Selected quality suppliers for anti-HFE (HFE) Antibodies
Did you look for something else?