HFE Products
(Hemochromatosis (HFE))
Categories
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Featured HFE Categories
HFE Antibodies
High quality antibodies with extensive validation data.
HFE Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HFE Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (5)
Cat. No.
ABIN561252
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC
Validations
- (2)
- (4)
Cat. No.
ABIN969192
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (3)
Cat. No.
ABIN516405
Quantity
50 μg
Datasheet
Datasheet
Recommended HFE Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306579
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3081393
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3120989
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HFE products
: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).: "Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer." in: PLoS ONE, Vol. 8, Issue 8, pp. e74075, (2013) (PubMed).
: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).
Synonyms and alternative names related to HFE
hemochromatosis (HFE), hemochromatosis (Hfe), HFE1, HH, HLA-H, MR2, MVCD7, TFQTL2Protein level used designations for HFE
- MHC class I-like protein HFE
- hereditary hemochromatosis protein
- hereditary hemochromatosis protein HLA-H
- high Fe
- RT1-CAFE
- hereditary hemochromatosis protein homolog
- hemochromatosis protein
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