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anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies

The protein encoded by HAVCR2 belongs to the immunoglobulin superfamily, and TIM family of proteins. Additionally we are shipping Hepatitis A Virus Cellular Receptor 2 Proteins (35) and Hepatitis A Virus Cellular Receptor 2 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
Anti-Rat HAVCR2 HAVCR2 363578  
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Top anti-Hepatitis A Virus Cellular Receptor 2 Antibodies at antibodies-online.com

Showing 10 out of 198 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HAVCR2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185571 (0.3 ug/ml) staining of human tonsil lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rat Alexa Fluor 700 FACS Detection of TIM-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mono-nuclear cells (PBMCs) were stained with Rat Anti-Human TIM-3 Alexa Fluor 700-conjugated Mono-clonal Antibody. 100 Tests Log in to see 6 to 7 Days
$400.31
Details
Human Rat Alexa Fluor 488 FACS Detection of TIM-3 in Human PBMCs Monocytes by Flow Cytometry. Human peripheral blood mononuclear cell (PBMC) monocytes were stained with Rat Anti-Human TIM-3 Alexa Fluor 488-conjugated Monoclonal Antibody. Detection of TIM-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with Recombinant Human IL-12. Dot plots were gated on lymphocytes. 100 Tests Log in to see 6 to 7 Days
$426.56
Details
Human Rat PE FACS Detection of TIM-3 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human TIM-3 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$426.56
Details
Human Rat PerCP FACS Detection of TIM-3 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human TIM-3 PerCP-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$479.06
Details
Human Rat Allophycocyanin FACS Detection of TIM-3 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human TIM-3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$479.06
Details
Human Rat Un-conjugated FACS Detection of TIM-3 in Human Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Rat Anti-Human TIM-3 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$357.00
Details
Mouse Rat PE FACS Detection of TIM-3 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse TIM-3 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$400.31
Details

HAVCR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hepatitis A Virus Cellular Receptor 2 Antibodies

  1. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Show all 15 references for ABIN4896442

  2. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Show all 5 references for ABIN4896438

  3. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for ABIN4899648

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 3 references for ABIN4896162

  5. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for ABIN4896439

  6. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Show all 2 references for ABIN4896440

  7. Human Polyclonal HAVCR2 Primary Antibody for ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  8. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

  9. Human Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

More Antibodies against Hepatitis A Virus Cellular Receptor 2 Interaction Partners

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (show LGALS9 Antibodies) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The results of our study showed that there is no significant association between TIM-1 (show ARHGEF5 Antibodies) 5383-5397ins/del and Multiple sclerosis (MS) (P = 0.38); however, the frequency of CT genotype of TIM-3 -1541C>T in patient group was significantly higher than the control group, and there was a significant association between CT genotype and MS

  2. this study shoes that Tim-3 level is significantly upregulated in monocytes from gastric cancer patients compared with those from healthy controls

  3. these results suggest that TIM3 is a novel therapeutic target and prognostic biomarker for esophageal squamous cell carcinoma (ESCC) and promotes metastasis of ESCC by inducing epithelial-mesenchymal transition via, at least partially, the Akt (show AKT1 Antibodies)/GSK-3beta (show GSK3b Antibodies)/Snail (show SNAI1 Antibodies) signaling pathway.

  4. Tim-3 facilitates osteosarcoma proliferation and metastasis through the NF-kappaB (show NFKB1 Antibodies) pathway and epithelial-mesenchymal transition.

  5. Studied the associations of T-cell immunoglobulin and mucin (show SLC13A2 Antibodies) domain-3 (Tim-3) polymorphisms and the alternate reading frame protein (F protein (show HPD Antibodies)) with the outcomes of HCV infection; findings suggest that the rs12186731 CT and rs13170556 TC/CC genotypes of Tim-3 provide potential protective effects with the F protein (show HPD Antibodies) in the outcomes of HCV infection and that these effects are related to sex and age.

  6. this study shows that the levels of expression of TIM-3 on CD4 (show CD4 Antibodies)+ T cells, CD8 (show CD8A Antibodies)+ T cells, CD56 (show NCAM1 Antibodies)+ T cells and in serum in patients with systemic lupus erythematosus are significantly higher than those of healthy controls

  7. ovarian tumor-infiltrating Treg cells were more immunosuppressive than their peripheral blood counterparts in a TIM3-dependent fashion.

  8. T cell immunoglobulin and mucin (show SLC13A2 Antibodies) domain-containing molecule 3 might participate in the progression of type 2 diabetes by its negative regulation on immune cells, and Tim-3 on CD14 (show NDUFA2 Antibodies)(+) monocytes serves as a novel biological marker for diabetes duration in type 2 diabetes patients.

  9. Increased Tim3 expression is associated with renal cell carcinoma (show MOK Antibodies).

  10. Hepatitis B virus surface antigen stimulation of human, monocyte-derived dendritic cells increases expression of Tim-3.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  2. in mice, TIM-3 is not essential for development of HDM (show HDAC3 Antibodies)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (show HDAC3 Antibodies)-induced chronic allergic airway inflammation.

  3. Authors found that a CD8 (show CD8A Antibodies)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  4. TIM4 (show TIMD4 Antibodies) binds TIM3 on the surface of polarized Th1 (show HAND1 Antibodies) cells to induce Th1 (show HAND1 Antibodies) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  5. The Gal-9 (show LGALS9 Antibodies)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  6. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  7. Tim-3 acts at a receptor-proximal point to enhance Lyn (show LYN Antibodies) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (show FCER1A Antibodies) ligation.

  8. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  9. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

  10. TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (show HIF1A Antibodies)-dependent manner.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Gene names and symbols associated with HAVCR2

  • hepatitis A virus cellular receptor 2 (HAVCR2) antibody
  • hepatitis A virus cellular receptor 2 (Havcr2) antibody
  • HAVcr-2 antibody
  • HAVCR2 antibody
  • KIM-3 antibody
  • MGC140131 antibody
  • TIM-3 antibody
  • tim3 antibody
  • TIMD-3 antibody
  • Timd3 antibody

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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