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anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies

The protein encoded by HAVCR2 belongs to the immunoglobulin superfamily, and TIM family of proteins. Additionally we are shipping Hepatitis A Virus Cellular Receptor 2 Proteins (34) and Hepatitis A Virus Cellular Receptor 2 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
Anti-Rat HAVCR2 HAVCR2 363578  
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Top anti-Hepatitis A Virus Cellular Receptor 2 Antibodies at antibodies-online.com

Showing 10 out of 194 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HAVCR2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185571 (0.3 ug/ml) staining of human tonsil lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HAVCR2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Liver WB Suggested Anti-HAVCR2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB HAVCR2 Antibody (Center) (ABIN1881402) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the HAVCR2 antibody detected the HAVCR2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat Un-conjugated IHC (fro), FACS   0.25 mg Log in to see 6 to 8 Days
$412.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: TIM-3 Antibody [ABIN269847] - HEK293 overexpressing HAVCR2 and probed with (mock transfection in first lane). Western Blot: TIM-3 Antibody [ABIN269847] - Analysis of TIM-3 using ABIN269847 at 0.3ug/ml in Human Tonsil lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Mouse Rat PE FACS 100 Tests Log in to see 3 to 4 Days
$427.06
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$323.13
Details

HAVCR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hepatitis A Virus Cellular Receptor 2 Antibodies

  1. Human Polyclonal HAVCR2 Primary Antibody for WB - ABIN1881402 : Cao, Zhu, Zhu, Li, Zhang, Xu, Zhang: Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer. in Cancer immunology, immunotherapy : CII 2010 (PubMed)
    Show all 5 references for ABIN1881402

  2. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN2476821 : Warner: Tobacco industry scientific advisors: serving society or selling cigarettes? in American journal of public health 1991 (PubMed)
    Show all 3 references for ABIN2476821

  3. Human Polyclonal HAVCR2 Primary Antibody for ELISA, WB - ABIN269847 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for IHC (fro), FACS - ABIN955215 : Sabatos, Chakravarti, Cha, Schubart, Sánchez-Fueyo, Zheng, Coyle, Strom, Freeman, Kuchroo: Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. in Nature immunology 2003 (PubMed)

  5. Human Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

More Antibodies against Hepatitis A Virus Cellular Receptor 2 Interaction Partners

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (show LGALS9 Antibodies) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Hepatitis B virus surface antigen stimulation of human, monocyte-derived dendritic cells increases expression of Tim-3.

  2. miR (show MLXIP Antibodies)-330-5p has a strong inhibitory effect on TIM-3 expression in acute myeloma leukaemia cell line

  3. Data show there was a negative correlation between soluble T cell immunoglobulin mucin (show SLC13A2 Antibodies) molecule 3 (sTim-3) and interferon-gamma (IFN-gamma (show IFNG Antibodies)) as well as between IFN-gamma (show IFNG Antibodies) and interleukin-4 (IL-4 (show IL4 Antibodies)), while sTim-3 and IL-4 (show IL4 Antibodies) were positively correlated.

  4. Data suggest that PD-1/PDCD1 (programmed cell death protein 1 (show PDCD1 Antibodies)) and Tim-3/HAVCR2 (hepatitis A virus cellular receptor 2) operate within the functional immune-modulatory network to promote Th2-(type-2 helper T cell-)mediated immunity at the maternal-fetal interface.

  5. Reduction of Tim-3(+) Treg cells (Tregs) in osteoarthritis patients resulted in less IL-10 (show IL10 Antibodies)-producing Tregs.

  6. findings support the use of Tim-3-Tim-3L blockade together with PD-1 (show PDCD1 Antibodies)-PD-L1 (show CD274 Antibodies) blockade to reverse tumor-induced T-cell exhaustion/dysfunction in patients with colorectal cancer.

  7. Tim-3 may be used as a novel target for increasing immune responses in RCC (show XRCC1 Antibodies) tumor microenvironment.

  8. Diffuse large B-cell lymphoma patients have high expression level of PD-1 (show PDCD1 Antibodies) and TIM-3, which are related to DLBCL staging. PD-1 (show PDCD1 Antibodies) and TIM-3 expression levels are also related to the efficiency of chemotherapy.

  9. The Gal-9 (show LGALS9 Antibodies)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  10. These data indicate that Tim-3 expression in NK cells can function as a prognostic biomarker in human lung adenocarcinoma and support that Tim-3 could be a new target for an immunotherapeutic strategy.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. in mice, TIM-3 is not essential for development of HDM (show HDAC3 Antibodies)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (show HDAC3 Antibodies)-induced chronic allergic airway inflammation.

  2. Authors found that a CD8 (show CD8A Antibodies)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  3. TIM4 (show TIMD4 Antibodies) binds TIM3 on the surface of polarized Th1 (show HAND1 Antibodies) cells to induce Th1 (show HAND1 Antibodies) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  4. The Gal-9 (show LGALS9 Antibodies)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  5. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  6. Tim-3 acts at a receptor-proximal point to enhance Lyn (show LYN Antibodies) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (show FCER1A Antibodies) ligation.

  7. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  8. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

  9. TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (show HIF1A Antibodies)-dependent manner.

  10. These data identify an IL-27 (show IL27 Antibodies)/NFIL3 (show NFIL3 Antibodies) signalling axis as a key regulator of effector T-cell responses via induction of Tim-3, IL-10 (show IL10 Antibodies) and T-cell dysfunction.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Gene names and symbols associated with HAVCR2

  • hepatitis A virus cellular receptor 2 (HAVCR2) antibody
  • hepatitis A virus cellular receptor 2 (Havcr2) antibody
  • HAVcr-2 antibody
  • HAVCR2 antibody
  • KIM-3 antibody
  • MGC140131 antibody
  • TIM-3 antibody
  • tim3 antibody
  • TIMD-3 antibody
  • Timd3 antibody

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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