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anti-Histidine-Rich Glycoprotein (HRG) Antibodies

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. Additionally we are shipping Histidine-Rich Glycoprotein Kits (14) and Histidine-Rich Glycoprotein Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRG 94175 Q9ESB3
HRG 3273 P04196
HRG 171016 Q99PS8
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Top anti-Histidine-Rich Glycoprotein Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Mouse Rat Un-conjugated WB   0.1 mg Log in to see 5 to 7 Days
$490.88
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$385.00
Details
Mouse Rat Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

HRG Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Histidine-Rich Glycoprotein Interaction Partners

Mouse (Murine) Histidine-Rich Glycoprotein (HRG) interaction partners

  1. HRG binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  2. Mice deficient in HRG have normal hemostasis, but demonstrate accelerated thrombosis via the contact system.

  3. mononuclear phagocytes have specific binding sites for HRG and that these cells are essential for uptake of HRG from blood and distribution of HRG in tissues. Thus, inflammatory cells mediate the effect of HRG on tumor growth and metastatic spread.

  4. Results show that HRG is a novel transcriptional target gene of FXR (show NR1H4 Antibodies) in human hepatoma cells, human upcyteVR primary hepatocytes and 3D human liver microtissues in vitro and in mouse liver in vivo.

  5. HRG-deficiency promotes tumor progression via enhanced platelet activity. HRG is a potent tumor suppressor, with capacity to attenuate the angiogenic switch, tumor growth, EMT (show ITK Antibodies) and subsequent metastatic spread, by regulating platelet activity.

  6. CD36 (show CD36 Antibodies)-mediated anti-angiogenic activity has context-dependent role in the tumor microenvironment in the presence of TSP-1 (show GZMA Antibodies) while HRG modulates this activity.

  7. HRG loss influences macrophage gene regulation, leading to excessive stimulation of tumor angiogenesis, suppression of tumor immune response, and increased tumor growth and metastatic spread

  8. the identification and characterization of a novel peptide, VTIP-peptide (VTIP-P), which binds and enhances the activation of CREM (show CREM Antibodies)/CREB (show CREB1 Antibodies)

  9. role for HRG as a regulator of inflammation and in the defense at the local site of bacterial infection

  10. HRG acts as a soluble adaptor molecule that binds to cells at sites of tissue injury, tumor growth, and angiogenesis

Human Histidine-Rich Glycoprotein (HRG) interaction partners

  1. HRG (show NRG1 Antibodies) attenuates DNA- and RNA-mediated FXII (show F12 Antibodies) activation, and FXI (show F11 Antibodies) activation by FXIIa or by thrombin (show F2 Antibodies), suggesting that HRG (show NRG1 Antibodies) down regulates the capacity of DNA and RNA to activate the intrinsic coagulation pathway.

  2. HRG (show NRG1 Antibodies) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  3. HRG (show NRG1 Antibodies) could inhibit hepatocellular carcinoma cell proliferation via the FGF-Erk1/2 (show MAPK1/3 Antibodies) signaling pathway by reducing Erk1/2 (show MAPK1/3 Antibodies) phosphorylation.

  4. Plasma free fatty acid levels influence Zn(2+) -dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin (show ALB Antibodies).

  5. mononuclear phagocytes have specific binding sites for HRG (show NRG1 Antibodies) and that these cells are essential for uptake of HRG (show NRG1 Antibodies) from blood and distribution of HRG (show NRG1 Antibodies) in tissues. Thus, inflammatory cells mediate the effect of HRG (show NRG1 Antibodies) on tumor growth and metastatic spread.

  6. Results show that HRG (show NRG1 Antibodies) is a novel transcriptional target gene of FXR (show NR1H4 Antibodies) in human hepatoma cells, human upcyteVR primary hepatocytes and 3D human liver microtissues in vitro and in mouse liver in vivo.

  7. genetic association study in Swedish population: Data suggest SNP in HRG (show NRG1 Antibodies) (rs2228243, A1042G) is associated with recurrent miscarriage in population studied; women heterozygous for HRG (show NRG1 Antibodies) A1042G SNP are protected from recurrent miscarriage. [PILOT STUDY]

  8. histidine-rich glycoprotein tissue RNA and serum protein might have a role in breast cancer

  9. HRG (show NRG1 Antibodies) does not exhibit the broad interactive properties that have been reported previously, suggesting that copurification of HRG (show NRG1 Antibodies)-binding partners or other impurities are responsible for some of the reported functional properties.

  10. Association between the histidine-rich glycoprotein (HRG) C633T single nucleotide polymorphism (SNP) and recurrent miscarriage was investigated. An association between homozygous carriers and recurrent miscarriage was detected.

Cow (Bovine) Histidine-Rich Glycoprotein (HRG) interaction partners

  1. the anti-angiogenic His/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner

Rabbit Histidine-Rich Glycoprotein (HRG) interaction partners

  1. The structure confirms that the N2 domain, which along with the N1 domain, forms an important molecular interaction site on HRG, possesses a cystatin (show CST3 Antibodies)-like fold composed of a 5-stranded antiparallel beta-sheet wrapped around a 5-turn alpha-helix.

Histidine-Rich Glycoprotein (HRG) Antigen Profile

Protein Summary

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Gene names and symbols associated with HRG

  • histidine-rich glycoprotein (HRG) antibody
  • histidine-rich glycoprotein (LOAG_12427) antibody
  • histidine-rich glycoprotein (Hrg) antibody
  • AI265597 antibody
  • AW413091 antibody
  • D16jh2 antibody
  • D18020 antibody
  • HPRG antibody
  • HRG1 antibody
  • HRGP antibody
  • THPH11 antibody

Protein level used designations for HRG

histidine-rich glycoprotein , histidine-proline-rich glycoprotein , histidine-rich glycoprotein 1

GENE ID SPECIES
460914 Pan troglodytes
699100 Macaca mulatta
9949886 Loa loa
100431732 Pongo abelii
100597044 Nomascus leucogenys
94175 Mus musculus
3273 Homo sapiens
171016 Rattus norvegicus
280820 Bos taurus
100009395 Oryctolagus cuniculus
100152095 Sus scrofa
770588 Gallus gallus
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