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Histone Deacetylase 8 (HDAC8) ELISA Kits

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Additionally we are shipping Histone Deacetylase 8 Antibodies (159) and Histone Deacetylase 8 Proteins (21) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HDAC8 55869 Q9BY41
HDAC8 70315 Q8VH37
HDAC8 363481 B1WC68
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Top Histone Deacetylase 8 ELISA Kits at antibodies-online.com

Showing 8 out of 13 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 2 to 3 Days
$450.00
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Human
0.625-40 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
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Mammalian
100 Tests Log in to see 2 to 3 Days
$409.50
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Eukaryotes
100 Tests Log in to see 2 to 3 Days
$514.50
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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100 Tests Log in to see 3 to 4 Days
$650.71
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More ELISA Kits for Histone Deacetylase 8 Interaction Partners

Human Histone Deacetylase 8 (HDAC8) interaction partners

  1. Our data exhibited an important role of HDAC8 in promoting gastric cancer tumorigenesis and identify this HDAC8 as a potential therapeutic target for the treatment of gastric cancer.

  2. The H143A and H142A/H143A mutants exhibit activity that is >80000-fold lower than that of wild-type HDAC8; the buried D176N and D176A mutants have significant catalytic effects, with more subtle effects caused by D183N and D183A

  3. cAMP signaling increases HDAC8 protein levels by reducing JNK (show MAPK8 ELISA Kits)-mediated autophagy and ubiquitin-proteasome-dependent degradation of the HDAC8 protein in H1299 lung cancer cells.

  4. Report the preparation and biophysical evaluation of five HDAC8 mutants: P91L, G117E, H180R, D233G, and G304R. Additionally, the double mutants D233G-Y306F and P91L-Y306F were prepared to enable cocrystallization of intact enzyme-substrate complexes.

  5. HDAC8 was increased in BRAF (show BRAF ELISA Kits)-mutated melanoma. Increased cytoplasmic HDAC8 immunoreactivity was independently associated with an improved survival from both diagnosis of primary melanoma and from first detection of stage IV disease to melanoma death

  6. findings show how HDAC8 drives nonalcoholic fatty liver disease-associated hepatocarcinogenesis

  7. Data reveal a role for miR-21-3p in regulating HDAC8 expression and Akt/Gsk3beta pathway in cardiac hypertrophy.

  8. Studied the kinetics, thermodynamics, and selectivity of Zn(II) and Fe(II) binding to HDAC8.

  9. HDAC8 X-ray crystal structures reveal that each Cornelia de Lange syndrome mutation causes local structural changes that compromise catalysis and/or thermostability.

  10. report the X-ray crystal structures of HDAC8 complexed with three synthetic analogues of Largazole in which the depsipeptide ester is replaced with a rigid amide linkage

Mouse (Murine) Histone Deacetylase 8 (HDAC8) interaction partners

  1. findings show how HDAC8 drives nonalcoholic fatty liver disease-associated hepatocarcinogenesis

  2. Data reveal a role for miR-21-3p in regulating HDAC8 expression and Akt/Gsk3beta pathway in cardiac hypertrophy.

  3. histone deacetylase 8 inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo

  4. HDAC8 and Sirt1 (show SIRT1 ELISA Kits) were also demonstrated to interact directly with ERRalpha (show ESRRA ELISA Kits) in vivo and to deacetylate and increase the DNA binding affinity of ERRalpha (show ESRRA ELISA Kits) in vitro.

  5. Global deletion of Hdac8 in mice leads to perinatal lethality due to skull instability, and deletion of Hdac8 in cranial neural crest cells and Hdac8 specifically represses the aberrant expression of homeobox (show PRRX1 ELISA Kits) transcription factors such as Otx2 (show OTX2 ELISA Kits) and Lhx1 (show LHX1 ELISA Kits)

Histone Deacetylase 8 (HDAC8) Antigen Profile

Antigen Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HDAC8

  • histone deacetylase 8 (CC1G_05302) antibody
  • histone deacetylase 8 (hdac8) antibody
  • histone deacetylase 8 (HDAC8) antibody
  • histone deacetylase 8 (Hdac8) antibody
  • histone deacetylase 8 (HDA08) antibody
  • 2610007D20Rik antibody
  • ATHDA8 antibody
  • CDLS5 antibody
  • HD8 antibody
  • HDA8 antibody
  • HDACL1 antibody
  • histone deacetylase 8 antibody
  • MRXS6 antibody
  • RGD1562895 antibody
  • RPD3 antibody
  • T27G7.14 antibody
  • T27G7_14 antibody
  • WTS antibody
  • wu:fd19a02 antibody
  • zgc:66196 antibody

Protein level used designations for HDAC8

histone deacetylase 8 , histone deacetylase-like 1 , HD8

GENE ID SPECIES
6017058 Coprinopsis cinerea okayama7130
100145561 Xenopus (Silurana) tropicalis
55869 Homo sapiens
70315 Mus musculus
363481 Rattus norvegicus
406740 Danio rerio
444137 Xenopus laevis
540666 Bos taurus
480957 Canis lupus familiaris
422182 Gallus gallus
100721893 Cavia porcellus
837366 Arabidopsis thaliana
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