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anti-Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) Antibodies

HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. Additionally we are shipping HPGD Kits (25) and HPGD Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HPGD 15446 Q8VCC1
HPGD 79242 O08699
HPGD 3248 P15428
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Top anti-HPGD Antibodies at antibodies-online.com

Showing 10 out of 135 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HPGD Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). HPGD (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185316 (0.1µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HPGD Antibody (C-term) (ABIN390765) in MDA-MB231 cell line lysates (35 µg/lane). HPGD (arrow) was detected using the purified polyclonal antibody. HPGD Antibody (C-term) (ABIN390765) IHC analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HPGD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HPGD. Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-HPGD mouse monoclonal antibody. (ABIN2454257) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HPGD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HPGD. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with HPGDfollowed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with HPGDfollowed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HPGD AntibodyTitration: 1.0 µg/mL  Positive Control: MDA-MB-435S Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 15-PGDH, antibody at 1:200 dilution. WB Image Sample (30μg whole cell lysate) A:Raji , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details

HPGD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HPGD Antibodies

  1. Human Polyclonal HPGD Primary Antibody for IF (p), IHC (p) - ABIN761711 : Wei, Yu, Shi, Zhang, Lian, Li, Shen, Xing, Zhu: 15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway. in Cellular signalling 2014 (PubMed)
    Show all 2 references for ABIN761711

  2. Human Polyclonal HPGD Primary Antibody for ELISA, WB - ABIN185316 : Coggins, Latour, Nguyen, Audoly, Coffman, Koller: Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus. in Nature medicine 2002 (PubMed)
    Show all 2 references for ABIN185316

  3. Human Polyclonal HPGD Primary Antibody for EIA, WB - ABIN453113 : Thill, Fischer, Becker, Cordes, Dittmer, Diedrich, Salehin, Friedrich: Prostaglandin metabolizing enzymes in correlation with vitamin D receptor in benign and malignant breast cell lines. in Anticancer research 2009 (PubMed)

More Antibodies against HPGD Interaction Partners

Mouse (Murine) Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) interaction partners

  1. 15-PGDH is downregulated in human hepatoma cells with a high COX-2 (show COX2 Antibodies) expression, in chemical and genetic murine models of hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and in human HCC (show FAM126A Antibodies) biopsies.

  2. Data from a mouse model suggest that expression of Hpgd protein in uterus is down-regulated in lipopolysaccharide/infection-induced embryo loss.

  3. prostaglandin E synthase (show PTGES Antibodies) (cPGES/p23 (show PTGES3 Antibodies)) acts as a regulatory factor for expression of a prostaglandin E2 -inactivating enzyme,15-hydroxyprostaglandin dehydrogenase ( 15-PGDH).

  4. I. sinclarii is effective in lowering blood glucose due to the upregulation of glucokinase (Gk (show GCK Antibodies)-rs1 (show RS1 Antibodies)) and downregulation of hydroxyprostaglandin dehydrogenase.

  5. OAT (show OAT Antibodies)-PG is proposed to be involved in the local PGE (show LIPF Antibodies)(2) clearance and metabolism for the inactivation of prostaglandin signals in the kidney cortex.

  6. novel tumor suppressive role for 15-PGDH due to loss of expression during colorectal tumor progression

  7. 15-Hydroxyprostaglandin dehydrogenase (show CBR1 Antibodies) has a role in suppressing colon tumorigenesis

  8. The intrarenal distribution of 15-PGDH and its interactions with COX-2 (show COX2 Antibodies) suggest that differential regulation of COX-2 (show COX2 Antibodies) and 15-PGDH plays a role in determining levels of prostaglandins involved in regulation of salt, volume, and blood pressure homeostasis.

Guinea Pig Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) interaction partners

  1. Data indicate that 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor TD88 could be a good effector on wound healing, especially in the aspects of prevention of scarring.

  2. The data indicate that decreased expression of 15-hydroxyprostaglandin dehydrogenase in the fetal membranes may contribute to the increase in intrauterine prostaglandin concentrations at term, stimulating the onset of labor.

Human Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) interaction partners

  1. A common mutation and a novel mutation in HPGD gene were identified to be responsible for primary hypertrophic osteoarthropathy

  2. Peroxisome proliferator-activated receptors (PPARs) play pivotal roles in maintenance of Chorionic NAD-dependent 15-hydroxy prostaglandin dehydrogenase (PGDH) expression in chorion during human pregnancy.

  3. Neoadjuvant chemotherapy could increase 15-PGDH expression in advanced gastric cancer patients, and 15-PGDH may serve as a candidate prognostic biomarker of advanced GC response to therapy.

  4. 15-PGDH mRNA levels were significantly higher in aorta samples from patients undergoing abdominal aortic aneurysm repair than in those from healthy multiorgan donors.

  5. Omega-3 polyunsaturated fatty acids upregulate the expression of 15-PGDH by inhibiting miR (show MLXIP Antibodies)-26a and miR (show MLXIP Antibodies)-26b.

  6. Multiple drug resistance-associated protein (show ABCC1 Antibodies) 4 (MRP4 (show ABCC4 Antibodies)), prostaglandin transporter (PGT (show SLCO2A1 Antibodies)), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer.

  7. Loss of PGDH expression is associated with esophageal squamous cell carcinoma and adenocarcinoma.

  8. A single nucleotide polymorphism in the 3' untranslated region (UTR (show UTS2R Antibodies)) of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene modifies mir (show MLXIP Antibodies)-485-5p binding in breast cancer.

  9. Case Reports: novel 2 (show TSPAN4 Antibodies)-bp homozygous deletion was found in exon 3 (c.310-311delCT) of HPGD gene in the patients with Primary hypertrophic osteoarthropathy.

  10. Tissues from 15-PGDH knockout mice demonstrate similar increased regenerative capacity.

HPGD Antigen Profile

Protein Summary

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HPGD

  • hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) antibody
  • hydroxyprostaglandin dehydrogenase 15-(NAD) (hpgd) antibody
  • 15-hydroxyprostaglandin dehydrogenase (pgdh) antibody
  • 15-hydroxyprostaglandin dehydrogenase (PTRG_03214) antibody
  • 15-hydroxyprostaglandin dehydrogenase (VDBG_09957) antibody
  • hydroxyprostaglandin dehydrogenase 15 (NAD) (Hpgd) antibody
  • 15-PGDH antibody
  • AV026552 antibody
  • MGC79454 antibody
  • MGC80546 antibody
  • PGDH antibody
  • PGDH1 antibody
  • PHOAR1 antibody
  • SDR36C1 antibody

Protein level used designations for HPGD

15-hydroxyprostaglandin dehydrogenase , hydroxyprostaglandin dehydrogenase 15-(NAD) , 15-hydroxyprostaglandin dehydrogenase [NAD(+)] , PGDH , prostaglandin dehydrogenase 1 , 15-PGDH , NAD-dependent 15-hydroxyprostaglandin dehydrogenase , 15-hydroxyprostaglandin dehydrogenase (NAD+) , NAD+-dependent 15-hydroxyprostaglandin dehydrogenase , short chain dehydrogenase/reductase family 36C, member 1 , NAD+ dependent 15-hydroxyprostaglandin dehydrogenase

GENE ID SPECIES
422567 Gallus gallus
446811 Xenopus laevis
461613 Pan troglodytes
486073 Canis lupus familiaris
493354 Xenopus (Silurana) tropicalis
100009687 Equus caballus
100156186 Sus scrofa
100172788 Pongo abelii
100196521 Salmo salar
6341441 Pyrenophora tritici-repentis Pt-1C-BFP
9531736 Verticillium alfalfae VaMs.102
15446 Mus musculus
79242 Rattus norvegicus
100135538 Cavia porcellus
3248 Homo sapiens
512259 Bos taurus
101112958 Ovis aries
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