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HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. Additionally we are shipping HPGD Kits (25) and HPGD Proteins (18) and many more products for this protein.
Showing 10 out of 139 products:
Human Polyclonal HPGD Primary Antibody for ICC, IF - ABIN152315
Giannoulias, Patel, Holloway, Lye, Tai, Challis: Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium. in The Journal of clinical endocrinology and metabolism 2002
Show all 22 references for ABIN152315
Human Polyclonal HPGD Primary Antibody for IF (p), IHC (p) - ABIN761711
Wei, Yu, Shi, Zhang, Lian, Li, Shen, Xing, Zhu: 15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway. in Cellular signalling 2014
Show all 2 references for ABIN761711
Human Polyclonal HPGD Primary Antibody for ELISA, WB - ABIN185316
Coggins, Latour, Nguyen, Audoly, Coffman, Koller: Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus. in Nature medicine 2002
Show all 2 references for ABIN185316
Human Polyclonal HPGD Primary Antibody for EIA, WB - ABIN453113
Thill, Fischer, Becker, Cordes, Dittmer, Diedrich, Salehin, Friedrich: Prostaglandin metabolizing enzymes in correlation with vitamin D receptor in benign and malignant breast cell lines. in Anticancer research 2009
15-PGDH is downregulated in human hepatoma cells with a high COX-2 (show COX2 Antibodies) expression, in chemical and genetic murine models of hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and in human HCC (show FAM126A Antibodies) biopsies.
Data from a mouse model suggest that expression of Hpgd protein in uterus is down-regulated in lipopolysaccharide/infection-induced embryo loss.
prostaglandin E synthase (show PTGES Antibodies) (cPGES/p23 (show PTGES3 Antibodies)) acts as a regulatory factor for expression of a prostaglandin E2 -inactivating enzyme,15-hydroxyprostaglandin dehydrogenase ( 15-PGDH).
I. sinclarii is effective in lowering blood glucose due to the upregulation of glucokinase (Gk (show GCK Antibodies)-rs1 (show RS1 Antibodies)) and downregulation of hydroxyprostaglandin dehydrogenase.
OAT (show OAT Antibodies)-PG is proposed to be involved in the local PGE (show LIPF Antibodies)(2) clearance and metabolism for the inactivation of prostaglandin signals in the kidney cortex.
novel tumor suppressive role for 15-PGDH due to loss of expression during colorectal tumor progression
15-Hydroxyprostaglandin dehydrogenase (show CBR1 Antibodies) has a role in suppressing colon tumorigenesis
The intrarenal distribution of 15-PGDH and its interactions with COX-2 (show COX2 Antibodies) suggest that differential regulation of COX-2 (show COX2 Antibodies) and 15-PGDH plays a role in determining levels of prostaglandins involved in regulation of salt, volume, and blood pressure homeostasis.
Data indicate that 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor TD88 could be a good effector on wound healing, especially in the aspects of prevention of scarring.
The data indicate that decreased expression of 15-hydroxyprostaglandin dehydrogenase in the fetal membranes may contribute to the increase in intrauterine prostaglandin concentrations at term, stimulating the onset of labor.
A common mutation and a novel mutation in HPGD gene were identified to be responsible for primary hypertrophic osteoarthropathy
Peroxisome proliferator-activated receptors (PPARs) play pivotal roles in maintenance of Chorionic NAD-dependent 15-hydroxy prostaglandin dehydrogenase (PGDH) expression in chorion during human pregnancy.
Neoadjuvant chemotherapy could increase 15-PGDH expression in advanced gastric cancer patients, and 15-PGDH may serve as a candidate prognostic biomarker of advanced GC response to therapy.
15-PGDH mRNA levels were significantly higher in aorta samples from patients undergoing abdominal aortic aneurysm repair than in those from healthy multiorgan donors.
Omega-3 polyunsaturated fatty acids upregulate the expression of 15-PGDH by inhibiting miR (show MLXIP Antibodies)-26a and miR (show MLXIP Antibodies)-26b.
Multiple drug resistance-associated protein (show ABCC1 Antibodies) 4 (MRP4 (show ABCC4 Antibodies)), prostaglandin transporter (PGT (show SLCO2A1 Antibodies)), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer.
Loss of PGDH expression is associated with esophageal squamous cell carcinoma and adenocarcinoma.
A single nucleotide polymorphism in the 3' untranslated region (UTR (show UTS2R Antibodies)) of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene modifies mir (show MLXIP Antibodies)-485-5p binding in breast cancer.
Case Reports: novel 2 (show TSPAN4 Antibodies)-bp homozygous deletion was found in exon 3 (c.310-311delCT) of HPGD gene in the patients with Primary hypertrophic osteoarthropathy.
Tissues from 15-PGDH knockout mice demonstrate similar increased regenerative capacity.
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
, hydroxyprostaglandin dehydrogenase 15-(NAD)
, 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
, prostaglandin dehydrogenase 1
, NAD-dependent 15-hydroxyprostaglandin dehydrogenase
, 15-hydroxyprostaglandin dehydrogenase (NAD+)
, NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
, short chain dehydrogenase/reductase family 36C, member 1
, NAD+ dependent 15-hydroxyprostaglandin dehydrogenase