You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Immediate Early Response 3 (IER3) Antibodies

IER3 functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Additionally we are shipping IER3 Proteins (6) and IER3 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IER3 8870 P46695
IER3 15937  
IER3 294235  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-IER3 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB IER3 Antibody (N-term)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the IER3 antibody detected the IER3 protein (arrow). IER3 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the IER3 antibody detected the IER3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of A549 cells using IER3 / IEX1 Antibody (N-term) Cat.-No AP52148PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of IER3 / IEX1 Antibody (N-term) Cat.-No AP52148PU-N with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 μg/ml. Western blot analysis of IEX1 in human brain tissue lysate with AP30400PU-N IEX1 antibody at (A) 2 and (B) 4 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with IER3 antibody ABIN213935 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-IEX1/Differentiation Dependent Gene 2 protein Polyclonal Antibody, Unconjugated (ABIN872466) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit APC ICC, FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 11 to 13 Days
$541.80
Details

IER3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,

Top referenced anti-IER3 Antibodies

  1. Human Polyclonal IER3 Primary Antibody for IHC, ELISA - ABIN1002470 : Kondratyev, Chung, Jung: Identification and characterization of a radiation-inducible glycosylated human early-response gene. in Cancer research 1996 (PubMed)
    Show all 4 references for ABIN1002470

  2. Human Polyclonal IER3 Primary Antibody for EIA, IHC (p) - ABIN499960 : Wu, Ao, Prasad, Wu, Schlossman: IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 4 references for ABIN499960

  3. Human Polyclonal IER3 Primary Antibody for FACS, IF - ABIN655735 : Fellay, Ge, Shianna, Colombo, Ledergerber, Cirulli, Urban, Zhang, Gumbs, Smith, Castagna, Cozzi-Lepri, De Luca, Easterbrook, Günthard, Mallal, Mussini, Dalmau, Martinez-Picado, Miro, Obel, Wolinsky, Martinson, Detels, Margolick, Jacobson, Descombes, Anton: Common genetic variation and the control of HIV-1 in humans. in PLoS genetics 2009 (PubMed)
    Show all 3 references for ABIN655735

  4. Human Polyclonal IER3 Primary Antibody for EIA, FACS - ABIN952818 : Ouakaa-Kchaou, Elloumi, Kochlef, Gargouri, Kharrat, Kilani, Ghorbel: Ovarian Crohn's disease. in Journal of Crohn's & colitis 2010 (PubMed)
    Show all 2 references for ABIN952818

More Antibodies against IER3 Interaction Partners

Human Immediate Early Response 3 (IER3) interaction partners

  1. interleukin-1beta (IL-1beta (show IL1B Antibodies))-induced IER3 expression is mediated by the ERK1/2 (show MAPK1/3 Antibodies) target, transcription factor Elk-1 (show ELK1 Antibodies).

  2. findings suggest that IER3 is a putative tumor suppressor in the cervix, and the c-Ab1/p73beta/IER3 axis is a novel and crucial signaling pathway that confers etoposide chemosensitivity.

  3. High expression of IER3 is associated with hepatocarcinoma.

  4. In human samples removed from failed AVF, there was a significant increase in IEX-1 expression localized to the adventitia.

  5. IEX-1 expression levels correlate with the severity of preeclampsia

  6. Studied the binding effect of hcmv-miR (show MLXIP Antibodies)-UL148D to the 3' untranslated region (3'UTR (show UTS2R Antibodies)) of IEX-1.Results showed that only one binding site in the 3'UTR (show UTS2R Antibodies) of IEX-1 was completely complementary to an 11nt sequence in the 5' terminus of hcmv-mir (show MLXIP Antibodies)-UL148D.

  7. the interference of IER3 with the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-Fyn (show FYN Antibodies) pathway represents a novel mechanism of Nrf2 (show GABPA Antibodies) regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.

  8. IEX-1 plays a role in suppression of apoptosis and protects cells by controlling sensitivity to TNFalpha (show TNF Antibodies) under both normal and inflammatory conditions.

  9. Altered IEX-1 expression can potentially be a new predictor of the malignant transformation and a prognostic indicator for cancer therapy.

  10. Changes of methylation status of gene IEX-1 promoter CpG island correlates with hematologic malignancies.

Mouse (Murine) Immediate Early Response 3 (IER3) interaction partners

  1. these results indicate that IER3 is a key player in expanding the pool of APC (show APC Antibodies) while highlighting the role of distinct effectors found in an obese microenvironment in this process

  2. Loss of IEX-1 results in reduced VNH accompanied with a decrease in proliferation, reduced fibroblast, myofibroblast, and Ly6C staining accompanied with increased apoptosis mediated through a reduction in Vegf-A (show VEGFA Antibodies)/Mcp-1 (show CPT1B Antibodies) axis and Mmp-9 (show MMP9 Antibodies).

  3. IER3 supports KRASG12D-associated oncogenesis in the pancreas by sustaining ERK1/2 (show MAPK1/3 Antibodies) phosphorylation via phosphatase PP2A (show PPP2R2B Antibodies) inhibition.

  4. Stress-induced hematopoietic failure in the absence of immediate early (show JUN Antibodies) response gene X-1 (IEX-1, IER3).

  5. the interference of IER3 with the PI3K/Akt (show AKT1 Antibodies)-Fyn (show FYN Antibodies) pathway represents a novel mechanism of Nrf2 (show NFE2L2 Antibodies) regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.

  6. IEX-1 has a role in activation of Erk (show EPHB2 Antibodies) and NF-kB pathways, which affects thrombopoietin (show THPO Antibodies)-promoted NHEJ DNA repair in hematopoietic stem cells

  7. Data suggest a role for the immediate early (show JUN Antibodies) response gene X-1 (IEX-1) in the control of colon epithelial homeostasis.

  8. Our present investigation shows that null mutation of IEX-1 promotes differentiation of Th17 cells but compromises the survival of Th1 (show HAND1 Antibodies) cells

  9. IER3 plays a complex and to some extent contradictory role in cell cycle control and apoptosis. Effects of IER3 relate to an interference with certain signalling pathways

  10. Mcl-1 (show MCL1 Antibodies) translocation to the nucleus is a general response to genotoxic stress that is strictly and timely controlled by IEX-1 in response to DNA damage. Loss of IEX-1 leads to genomic instability.

IER3 Antigen Profile

Protein Summary

This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Gene names and symbols associated with IER3

  • immediate early response 3 (IER3) antibody
  • immediate early response 3 (Ier3) antibody
  • AI663993 antibody
  • cI-3 antibody
  • DIF-2 antibody
  • Dif2 antibody
  • gly96 antibody
  • IER3 antibody
  • IEX-1 antibody
  • IEX-1L antibody
  • Iex1 antibody
  • Ler3 antibody
  • Prg1 antibody

Protein level used designations for IER3

immediate early response 3 , radiation-inducible immediate-early gene IEX-1 , ATP-binding cassette, sub-family F (GCN20), member 1 , PACAP-responsive gene 1 protein , anti-death protein , differentiation-dependent gene 2 protein , expressed in pancreatic carcinoma , gly96, mouse, homolog of , immediate early protein GLY96 , immediate early response 3 protein , immediately early gene X-1 , protein DIF-2 , cAMP inducible gene 3

GENE ID SPECIES
481708 Canis lupus familiaris
505455 Bos taurus
701939 Macaca mulatta
743437 Pan troglodytes
8870 Homo sapiens
15937 Mus musculus
294235 Rattus norvegicus
462547 Pan troglodytes
Selected quality suppliers for anti-IER3 (IER3) Antibodies
Did you look for something else?