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anti-Inosine Triphosphatase (ITPA) Antibodies

The protein encoded by ITPA hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. Additionally we are shipping Inosine Triphosphatase Proteins (22) and Inosine Triphosphatase Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITPA 3704 Q9BY32
ITPA 311422 D3ZW55
ITPA 16434 Q9D892
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Top anti-Inosine Triphosphatase Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ITPA Antibody (N-term) (ABIN651135) in A375 cell line lysates (35 µg/lane). ITPA (arrow) was detected using the purified polyclonal antibody. ITPA Antibody (N-term) (ABIN651135) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using ITPA antibody. 200 μL Log in to see 9 Days
$588.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ITPA is 3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image ITPase antibody [N1C3] detects ITPase protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. ITPase antibody [N1C3] , dilution: 1:500. WB Image Sample(30 ug whole cell lysate) A:293T B:Hep G2 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB ITPA Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ITPA antibody detected the ITPA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$581.17
Details

ITPA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Inosine Triphosphatase Antibodies

  1. Mouse (Murine) Polyclonal ITPA Primary Antibody for IHC, WB - ABIN3021765 : Lin, McLennan, Ying, Wang, Gu, Jin, Wu, Liu, Yuan, Tang, Xie, Mao: Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN3021765

  2. Human Polyclonal ITPA Primary Antibody for FACS, IF - ABIN651135 : Fellay, Thompson, Ge, Gumbs, Urban, Shianna, Little, Qiu, Bertelsen, Watson, Warner, Muir, Brass, Albrecht, Sulkowski, McHutchison, Goldstein: ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. in Nature 2010 (PubMed)
    Show all 2 references for ABIN651135

  3. Human Monoclonal ITPA Primary Antibody for ELISA - ABIN517268 : Vroemen, Munnix, Bakker, Bierau, Huts, Leers: A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012 (PubMed)

More Antibodies against Inosine Triphosphatase Interaction Partners

Human Inosine Triphosphatase (ITPA) interaction partners

  1. Genetic variants in inosine triphosphatase (ITPA) gene have been linked to the haemolytic anaemia induced by peg (show PAEP Antibodies)-interferon (show IFNA Antibodies) and ribavirin treatment.

  2. The association of IL28B (show IL28B Antibodies) and APOH (show APOH Antibodies) single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

  3. The identification of ITPA protective and SLC29A1 (show SLC29A1 Antibodies) risk genotypes still appears to be a current methodology in Ribavirin dosing during hepatitis C virus therapy with direct acting antiviral agents

  4. ITPA SNPs in Brazilian patients receiving antiviral therapy for chronic hepatitis had a great propensity for developing ribavirin-induced anaemia.

  5. genotyping of ATIC (show ATIC Antibodies) rs2372536 and ITPA rs1127354 variants or measuring ITPA activity could be useful to predict methotrexate response in children with juvenile idiopathic arthritis.

  6. Recessive ITPA mutations were associated with early infantile encephalopathy.

  7. results showed that patients with aberrant ITPase genotype (mutant homozygous or heterozygous), more likely to be myelosuppressed and show liver toxicity after treatment with 6-Mercaptopurine

  8. The ITPA SNP rs1127354 is a useful predictor of ribavirin-induced anemia in Taiwanese patients and may be related to more severe decreases in platelet counts during the early stage of HCV combination therapy.

  9. Results indicate a strong, significant, and independent role of VDR (show CYP27B1 Antibodies) in the early development of ribavirin-induced anemia and confirm the ITPA function in the prediction of anemia at week 4.

  10. ITPA polymorphisms are associated with an improved likelihood of achieving sustained virological response resulting from the reduced risk of relapse following IFN and ribavirin combination therapy for HCV infection

Mouse (Murine) Inosine Triphosphatase (ITPA) interaction partners

  1. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  2. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Inosine Triphosphatase (ITPA) Antigen Profile

Protein Summary

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ITPA

  • inosine triphosphatase (itpa) antibody
  • inosine triphosphatase (LOC100345066) antibody
  • inosine triphosphatase (LOC733043) antibody
  • inosine triphosphatase (LOC100157088) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa) antibody
  • LOC100283993 (pco148511) antibody
  • nucleoside-triphosphatase, cancer-related (NTPCR) antibody
  • 2010016I08Rik antibody
  • AU020102 antibody
  • C1orf57 antibody
  • C20orf37 antibody
  • DDBDRAFT_0215619 antibody
  • DDBDRAFT_0238062 antibody
  • DDB_0215619 antibody
  • DDB_0238062 antibody
  • dJ794I6.3 antibody
  • HCR-NTPase antibody
  • HLC14-06-P antibody
  • Itp antibody
  • ITPase antibody
  • NTPase antibody
  • RP4-678E16.2 antibody
  • si:ch73-18j6.1 antibody
  • si:dkey-19f21.1 antibody

Protein level used designations for ITPA

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside-triphosphate diphosphatase , putative oncogene protein HLC14-06-P , nucleoside-triphosphate pyrophosphatase , nucleoside triphosphate pyrophosphatase , inosine triphosphatase A , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , Inosine triphosphatase , PCO148511_ov , hypothetical protein , pco148511(169) , cancer-related nucleoside-triphosphatase , human cancer-related NTPase , nucleoside triphosphate phosphohydrolase , nucleoside-triphosphatase C1orf57

GENE ID SPECIES
8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
3704 Homo sapiens
311422 Rattus norvegicus
16434 Mus musculus
613653 Bos taurus
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
100283993 Zea mays
84284 Homo sapiens
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