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IGFBPI is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. Additionally we are shipping Insulin-Like Growth Factor Binding Protein 1 Kits (99) and Insulin-Like Growth Factor Binding Protein 1 Proteins (45) and many more products for this protein.
Showing 10 out of 192 products:
hypoxia causes PGC (show PGC Antibodies) migration defect by inhibiting IGF signaling through the induction of IGFBP-1
The insulin-like growth factor binding protein 1 (29-31kDa)is similarities to mammalian.
HIF-1 (show HIF1A Antibodies) mediates hypoxia-induced IGFBP-1 gene expression in early development by selectively interacting with the hypoxia response elements and its adjacent HIF-1 (show HIF1A Antibodies) ancillary sequence.
TGE (show TGM3 Antibodies) duplicated IGFBP-1 may provide additional flexibility in fine-tuning insulin (show INS Antibodies)-like growth factor signaling activities under hypoxia and other catabolic conditions.
IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor in the rhesus monkey.
the hepatokine IGFBP1 is a critical liver-bone hormonal relay that promotes osteoclastogenesis and bone resorption as well as an essential mediator of FGF21 (show FGF21 Antibodies)-induced bone loss
There was a positive correlation between the IGFBP1 levels of and those of inflammatory mediators in HIV Infections.
The amino acid response and mTOR (show FRAP1 Antibodies) independently regulate IGFBP-1 secretion and phosphorylation in response to decreased amino acid availability.
Insulin-like growth factor 1 receptor (show IGF1R Antibodies) blockade can inhibit glioblastoma growth by different mechanisms, including direct effects on the tumor cells as well as indirect anti-angiogenic effects.
HIF-2alpha (show EPAS1 Antibodies) acts as an important negative regulator of hepatic lymphangiogenesis in vitro and in vivo by inducing IGFBP1.
gene expression analysis of human breast tumors showed that high expression of IGFBP mRNA was strongly correlated with good prognosis but not when MMP9 (show MMP9 Antibodies) mRNA was also highly expressed
study shows up-regulation of MCSF (show CSF1 Antibodies) in GBM via a SYK (show SYK Antibodies)-PI3K (show PIK3CA Antibodies)-NFkappaB (show NFKB1 Antibodies)-dependent mechanism and identifies IGFBP1 released by microglial cells as a novel mediator of MCSF (show CSF1 Antibodies)-induced angiogenesis
Activation of IGFBP1 by pregnane X receptor (show NR1I2 Antibodies) alters the morphology of hepatocellular carcinoma cells and regulates cell migration.
IGFBP1 in epithelial circulating tumor cells as a potential response marker to selective internal radiation therapy in hepatocellular carcinoma
Data suggest that expression of IGFBP1 in hepatocytes can be regulated by carnosine, a dietary factor; carnosine down-regulates expression of IGFBP1 in Hep G2 cells; mechanism involves suppression of HIF1A (hypoxia inducible factor 1 alpha subu (show HIF1A Antibodies)nit).
Data suggest expression of Igfbp1 in liver is regulated by dietary factors; carnosine supplementation down-regulates expression of Igfbp1 in liver of obese/diabetic mice; mechanism involves suppression of Hif1a (hypoxia inducible factor 1 alpha (show HIF1A Antibodies)).
During the two week starvation period, both the levels of plasma IGF-1 (show IGF1 Antibodies) and IGFBP-1 decreased.
These results show that RTEF-1 (show TEAD4 Antibodies)-stimulated IGFBP-1 expression may be central to the mechanism by which RTEF-1 (show TEAD4 Antibodies) attenuates blood glucose levels.
Global deletion of Igfbp1 in a c-Myc (show MYC Antibodies) transgenic model did not accelerate the development of prostate cancer. Global Igfbp1 deletion did result in a significant increase in body weight and body fat mass.
IGFBP-1 functions as a critical hepatic survival factor in the liver by reducing the level of proapoptotic signals
IGFBP-1 may support liver regeneration at least in part via its effect on MAPK/ERK (show MAPK1 Antibodies) and C/EBP beta (show CEBPB Antibodies) activities. These findings are the first demonstration of the involvement of IGFBP-1 in the regulation of in vivo mitogenic signaling pathways.
Induction of IFGBP1 expression by amino acid deprivation of HepG2 hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR (show UTS2R Antibodies).
high concentrations of circulating IGFBP-1 are sufficient to cause fetal growth restriction in an animal model
the IGFBP-1 gene is a primary target of peroxisome proliferator-activated receptors
Allantoic fluid levels of IGFBP-1 were increased in nuclear transfer pregnancies
IGFBP1 is a common endometrial marker of conceptus elongation in sheep and cattle and most likely regulates conceptus elongation by stimulating migration and attachment of the trophectoderm
Results of fluorescence in situ and radiation hybrid (RH) mapping assigned this gene to porcine chromosome (SSC (show CYP11A1 Antibodies)) 18q24-qter.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
insulin-like growth factor binding protein 1
, insulin-like growth factor binding protein-1
, IGF-binding protein 1
, alpha-pregnancy-associated endometrial globulin
, amniotic fluid binding protein
, binding protein-25
, binding protein-26
, binding protein-28
, growth hormone independent-binding protein
, insulin-like growth factor-binding protein 1
, placental protein 12
, INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1)