You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) Antibodies

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. Additionally we are shipping IGFBP3 Kits (111) and IGFBP3 Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGFBP3 3486 P17936
IGFBP3 16009  
IGFBP3 24484 P15473
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-IGFBP3 Antibodies at antibodies-online.com

Showing 10 out of 189 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238551 (0.02µg/ml) staining of Human Breast cancer lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Hamster Rabbit Un-conjugated WB IGFBP3-S183(ABIN391976) western blot analysis in mouse stomach tissue lysates (15 µg/lane).This demonstrates the IGFBP antibody detected IGFBP protein (arrow). IGFBP3-S183(ABIN391976) western blot analysis in CHO tissue lysates (15 µg/lane).This demonstrates the IGFBP antibody detected IGFBP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-IGFBP3 Antibody (N-term) (ABIN391974) in HepG2 cell line lysates (35 µg/lane). IGFBP3(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with IGFBP3 Antibody (N-term) (ABIN391974), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with IGFBP3 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of IGFBP3(arrow) using rabbit polyclonal IGFBP3 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with IGFBP gene (Lane 2) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with AP14345PU-N IGFBP3 Antibody (N-term) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of AP14345PU-N IGFBP3 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). IGFBP3(arrow) was detected using the purified Pab (1/60 dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled Anti-IGFBP3 Polyclonal Antibody, Unconjugated (ABIN686497) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin-embedded rat brain labeled with Anti-IGFBP3 Polyclonal Antibody, Unconjugated (ABIN686497) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG,Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of IGFBP-3 on a human plasma lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human IGFBP-3 antibody. Immunofluorescence staining of human fibroblasts. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti- IGFBP3 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details

IGFBP3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , , , , , , , , , , ,
Mouse (Murine) , , ,
, ,
,
, , , , , , , , , , ,
Rat (Rattus) , ,
,

, , , , , , , , , , ,

Top referenced anti-IGFBP3 Antibodies

  1. Human Monoclonal IGFBP3 Primary Antibody for IF, WB - ABIN968565 : Campbell, Durham, Hayes, Suwanichkul, Powell: Insulin-like growth factor-binding protein-3 binds fibrinogen and fibrin. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN968565

  2. Human Polyclonal IGFBP3 Primary Antibody for WB - ABIN871771 : Roghani, Segovia, Whitechurch, Binoux: Purification from human cerebrospinal fluid of insulin-like growth factor binding proteins (IGFBPs). Isolation of IGFBP-2, an altered form of IGFBP-3 and a new IGFBP species. in Growth regulation 1993 (PubMed)
    Show all 3 references for ABIN871771

  3. Human Polyclonal IGFBP3 Primary Antibody for EIA, IHC (p) - ABIN359861 : Muzumdar, Ma, Fishman, Yang, Atzmon, Vuguin, Einstein, Hwang, Cohen, Barzilai: Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action. in Diabetes 2006 (PubMed)
    Show all 2 references for ABIN359861

  4. Human Polyclonal IGFBP3 Primary Antibody for EIA, IHC (p) - ABIN359863 : Novosyadlyy, Dargel, Scharf: Expression of insulin-like growth factor-I and insulin-like growth factor binding proteins during thioacetamide-induced liver cirrhosis in rats. in Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005 (PubMed)
    Show all 2 references for ABIN359863

  5. Human Polyclonal IGFBP3 Primary Antibody for IF (p), IHC (p) - ABIN686497 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)

  6. Human Polyclonal IGFBP3 Primary Antibody for ELISA, WB - ABIN238551 : Lin, Manson, Lee, Cook, Buring, Zhang: Intakes of calcium and vitamin D and breast cancer risk in women. in Archives of internal medicine 2007 (PubMed)

More Antibodies against IGFBP3 Interaction Partners

Zebrafish Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. insulin-like growth factor binding protein 3 exerts its ligand-independent action by antagonizing bone morphogenetic protein 2 (show BMP4 Antibodies) in zebrafish embryos

  2. IGFBP-3 plays an important role in regulating pharyngeal cartilage and inner ear development and growth in zebrafish.

Human Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. Study showed that IGFBP3 is dramatically induced in pancreatic tumors, and is abundantly produced in pancreatic cancer cells, causing muscle wasting through both impaired myogenesis via, at least, inhibition of IGF/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling.

  2. The ratios of IGF-I (show IGF1 Antibodies)/IGFBP-3 were increased in postmenopausal Taiwanese women with breast cancer, irrespective of their ages, ER and PR statuses, and HER2 (show ERBB2 Antibodies) expression.

  3. Higher IGF-I (show IGF1 Antibodies) levels among postmenopausal women and an elevated IGF-I:IGFBP-3 ratio among all women were associated with higher TDLU counts ; these associations were strongest among women with elevated mammographic density

  4. Insulin (show INS Antibodies)-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells via integrin beta1 signaling.

  5. endogenous IGFBP-3 is a p53 (show TP53 Antibodies) target that plays a role in breast cancer cell responsiveness to DNA damaging therapy

  6. Metformin resulted in a significant reduction of IGF-1 (show IGF1 Antibodies), IGF-1 (show IGF1 Antibodies): IGFBP-3 molar ratio, insulin (show INS Antibodies), FBG and HOMA-IR. On the other hand, metformin caused a significant increase of IGFBP-3.

  7. Data indicate that IGF-binding protein 3 (IGFBP3) and F3 gene expression levels in formalin fixed paraffin embedded (FFPE) prostate cancer tissue would provide an improved survival prediction for prostate cancer patients.

  8. calcineurin (show PPP3CA Antibodies) in astrocytes was activated by Amyloid beta, leading to IGFBP-3 release.

  9. Circulating levels of IGF-1 (show IGF1 Antibodies), IGFBP-3 and their molar ratio were not associated with the risk of occurrence of colorectal adenoma

  10. Independent of obesity, high insulin (show INS Antibodies) levels but reduced levels of IGFBP-3 were associated with increased lung cancer risk in current smokers.

Mouse (Murine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. IGFBP-3 is an aggravating factor during hepatic ischemia-repefusion injury.

  2. An increase in IGFBP-3 post-trauma may play an important role in limiting trauma-induced inflammatory and apoptotic pathways leading to retinal damage.

  3. Even though knockout of IGFBP-3 is associated with only a subtle phenotype under control conditions, our results reveal that loss of this gene has measurable effects on breast carcinogenesis and breast cancer metastasis.

  4. Igfbp3 is a marker for culture-activated hepatic stellate cells and plays a role in HSC (show FUT1 Antibodies) migration.

  5. Igfbp2 (show IGFBP2 Antibodies)-5 are expressed in distinct and complementary patterns during cochlear development.

  6. IGFBP-3 has novel protective effects on retinal and systemic vasculature and may be a therapeutic candidate for ocular complications such as diabetic retinopathy.

  7. IGFBP-3 activates inhibitory Smad (show SMAD1 Antibodies) signaling in 3T3-L1 cells and that endogenous IGFBP-3 modulates their adipogenic differentiation by regulating cell sensitivity towards the inhibitory effect of TGFbeta (show TGFB1 Antibodies).

  8. Wnt (show WNT2 Antibodies) signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3.

  9. IGFBP-3 positively and negatively impacts on IGF1 (show IGF1 Antibodies)-induced lung cancer development.

  10. Bone morphogenetic protein-1 (show BMP1 Antibodies) processes insulin-like growth factor-binding protein 3.

Cow (Bovine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. These data suggest that endogenous IGFBP-3 plays a role in intrinsic apoptosis by facilitating phosphorylation and nuclear export of Nur77 (show NR4A1 Antibodies) to the cytoplasm where it exerts its apoptotic effect.

  2. The present study suggests that the insulin (show INS Antibodies) like growth factor (IGF) system or imbalances between IGF and IGF binding (show HTRA1 Antibodies) proteins may be involved in cystic ovary disease of cattle.

  3. spatial and temporal patterns of expression of IGFBP-2 (show IGFBP2 Antibodies) and -3 were markedly altered in the placentomes of nuclear transfer pregnancies

  4. stimulation of IGFBP-3 mRNA levels by mitogens is regulated through both the PI3K and MAPK (show MAPK1 Antibodies) pathways in bovine mammary epithelial cells

  5. Preincubation of erythroid cells with thrombospondin 1 (show THBS1 Antibodies) eliminated the inhibitory activity of IGFBP-3

  6. GH, IGF-I (show IGF1 Antibodies) and IGF-IBP3 regulated the growth and development traits in different growth period.

  7. delivery of insulin-like growth factor-1 (IGF-1 (show IGF1 Antibodies), delivered at concentrations of 0, 10, 50, and 100 ng/mL) affects the endogenous expression of IGF-1 (show IGF1 Antibodies), its receptor (IGF-1R (show IGF1R Antibodies)), and a well known IGF-1 (show IGF1 Antibodies) binding protein (IGFBP-3) by articular chondrocytes

  8. Multivariable adjusted analyses did not reveal a statistically significant linear relationship between IGF1 (show IGF1 Antibodies) or IGFBP3 concentrations or their molar ratio and risk of myocardial infarction

  9. Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.

Pig (Porcine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. IGF-I (show IGF1 Antibodies), IGF-II, and IGFBP-3 mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. Increased oxidative stress from high glucose enhances IGFBP-3 expression, inducing apoptosis

  3. Even though LRP-1 (show LRP1 Antibodies) mRNA and protein levels were dramatically reduced in LRP-1 (show LRP1 Antibodies)-silenced L6 cells compared with mock-silenced controls, rpIGFPB-3 suppressed proliferation rate to the same extent in both LRP-1 (show LRP1 Antibodies)-silenced and mock-silenced cultures.

  4. cloning and sequencing; regulation of IGFBP-3 transcription by FSH (show BRD2 Antibodies) suggests a role for IGFBP-3 in follicular development that may be independent of IGF-I (show IGF1 Antibodies)

  5. Follicle-stimulating hormone stimulation of IGFBP-3 transcription is mediated by cAMP via the PKA pathway and requires the P1-3 kinase and likely the MAPK (show MAPK1 Antibodies) pathways.

  6. TAF4b may thus be the TFIID (show TBP Antibodies) component that binds to the TBP (show TBP Antibodies) site on the IGFBP-3 promoter and is essential for FSH (show BRD2 Antibodies) induction of IGFBP-3.

  7. The results suggest that the expression of IGF2 and IGFBP3 mRNA in the adipose tissue of pigs exhibits specific developmental changes and different patterns between the two pig breeds.

  8. allelic frequency of TAT (show C6orf134 Antibodies) in Chinese breeds was over 50%; allelic frequency of GGC (show GGCT Antibodies) was over 50% in all European breeds. TAT/TAT (show C6orf134 Antibodies) pigs scored higher in meat color than GGC/GGC (show GGCT Antibodies) pigs. results implied that IGFBP-3 may affect meat quality & carcass traits.

Horse (Equine) Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) interaction partners

  1. Data suggest that metabolism of IGFBP3, IGF1 (insulin-like growth factor I), and IGF2 (insulin-like growth factor II) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).

IGFBP3 Antigen Profile

Protein Summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with IGFBP3

  • insulin-like growth factor binding protein 3 (igfbp3) antibody
  • insulin-like growth factor binding protein 3 (IGFBP-3) antibody
  • insulin-like growth factor binding protein 3 (IGFBP3) antibody
  • insulin-like growth factor binding protein 3 (LOC100220315) antibody
  • insulin-like growth factor binding protein 3 (LOC100305016) antibody
  • insulin-like growth factor binding protein 3 (Igfbp3) antibody
  • insulin-like growth factor binding protein-3 (IGFBP-3) antibody
  • AI649005 antibody
  • BP-53 antibody
  • IBP3 antibody
  • IGF-BP3 antibody
  • IGFBP-3 antibody
  • igfbp3 antibody
  • IGgfbp3 antibody
  • zgc:91788 antibody

Protein level used designations for IGFBP3

insulin-like growth factor-binding protein 3 , insulin-like growth factor binding protein 3 , IBP-3 , IGF-binding protein 3 , IGFBP-3 , acid stable subunit of the 140 K IGF complex , binding protein 29 , binding protein 53 , growth hormone-dependent binding protein , insulin-like growth factor binding protein-3 , insulin-like growth factor-binding protein (IGF-BP3)

GENE ID SPECIES
403079 Danio rerio
443497 Ovis aries
463396 Pan troglodytes
696868 Macaca mulatta
100136304 Oncorhynchus mykiss
100173070 Pongo abelii
100220315 Taeniopygia guttata
100305016 Ictalurus punctatus
3486 Homo sapiens
491618 Canis lupus familiaris
16009 Mus musculus
282261 Bos taurus
24484 Rattus norvegicus
420790 Gallus gallus
448812 Sus scrofa
100714097 Cavia porcellus
100286737 Ovis aries
100034155 Equus caballus
Selected quality suppliers for anti-IGFBP3 (IGFBP3) Antibodies
Did you look for something else?