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The product of ITGA4 belongs to the integrin alpha chain family of proteins. Additionally we are shipping Integrin alpha 4 Kits (8) and Integrin alpha 4 Proteins (2) and many more products for this protein.
Showing 10 out of 251 products:
Human Monoclonal ITGA4 Primary Antibody for FACS, ICC - ABIN4900793
Zhang, Fu, Hu, Dong, Song, Song: C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation. in Scientific reports 2015
Show all 4 references for ABIN4900793
Human Polyclonal ITGA4 Primary Antibody for WB - ABIN871718
Iida, Meijne, Oegema, Yednock, Kovach, Furcht, McCarthy: A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion. in The Journal of biological chemistry 1998
Show all 2 references for ABIN871718
Human Polyclonal ITGA4 Primary Antibody for IF (p), IHC (p) - ABIN677063
Tong, Dou, Wang, Yu, Wu, Lu, Chou, Wang, Kong, Dai, Xia: Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues. in Toxicology and applied pharmacology 2014
Show all 2 references for ABIN677063
Mouse (Murine) Monoclonal ITGA4 Primary Antibody for FACS - ABIN4900254
Richard, Roy, Audoy-Rémus, Tremblay, Vallières: Crawling phagocytes recruited in the brain vasculature after pertussis toxin exposure through IL6, ICAM1 and ITGαM. in Brain pathology (Zurich, Switzerland) 2011
Human Monoclonal ITGA4 Primary Antibody for FACS - ABIN4898624
Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011
Human Polyclonal ITGA4 Primary Antibody for FACS, IF (p) - ABIN671301
Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014
Administration of a novel recombinant antibody against alpha4beta7 gut (show GUSB Antibodies)-homing integrin during acute lentiviral infection prevents mobilization of cell lineages of the innate immune system and protects the gut (show GUSB Antibodies) tissues from acute lentiviral infection.
The results uncovered a previously unknown role of integrin a4b7-MAdCAM-1 (show MADCAM1 Antibodies) interactions as drivers of colitis by directing inflammatory monocytes into the colon.
These results suggest that Tie2 (show TEK Antibodies) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).
ITGA4 expression enhances metastasis in MYCN (show MYCN Antibodies) low neuroblastoma (show ARHGEF16 Antibodies).
CD49d-high-expressing Th1 (show HAND1 Antibodies) memory phenotype CD4 (show CD4 Antibodies)+ T cells with enhanced B cell helper activity develop early in the peritoneal cavity.
Data suggest that bortezomib mobilizes hematopoietic stem cells (HSPCs) by modulation of the integrin alpha4beta1 (VLA)-4/vascular cell adhesion molecule-1 (VCAM-1 (show VCAM1 Antibodies)) axis.
Consistent with a role of alpha4beta7 in the generation of intestinal mononuclear phagocytes, bone marrow cells from beta7(-/-) mice poorly reconstituted small intestine retinoic acid (RA)-producing CD11c (show ITGAX Antibodies)(hi) dendritic cells.
SP/drug efflux functionality of hematopoietic progenitors is controlled by mesenchymal niche through VLA-4/CD44 (show CD44 Antibodies) axis.
We conclude that integrin alpha4beta1 is necessary for CD4 (show CD4 Antibodies)(+) T cell-mediated protection against C. trachomatis infection in the genital mucosa.
Mobilization of bone marrow-derived cells by G-CSF (show CSF3 Antibodies) boosted migration along the VCAM-1 (show VCAM1 Antibodies)/VLA-4 axis and reduced apoptosis of cardiomyocytes.
PI3-kinase gamma (show PIK3CG Antibodies) promotes Rap1a (show RAP1A Antibodies)-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.
Data show tht Rho kinase (show ROCK1 Antibodies) (ROCK) activity was increased by inhibiting integrin alpha4 with human umbilical vein endothelial cells (HUVECs) and hypoxia.
These data showed that Mycobacterium tuberculosis ESAT-6 and ESAT-6/CFP (show CFP Antibodies)-10 fusion proteins could induce adhesion of macrophages to fibronectin (show FN1 Antibodies) through alpha4beta1 integrin.
Enhanced susceptibility of activated endocervical CD4 (show CD4 Antibodies)+ T cells to HIV may be related to increased CCR5 (show CCR5 Antibodies) expression by these cell subsets, but did not appear to be due to direct interaction of integrins a4b7 or a4b1 with HIV envelope.
knockdown of PTTG1 (show PTTG1 Antibodies) increased expression of integrin alpha 4 (ITGA4), ITGA5 (show ITGA5 Antibodies), and integrin beta 1 (ITGB1 (show ITGB1 Antibodies)); otherwise, RhoA (show RHOA Antibodies) expression was significantly decreased
Integrin alpha 2 (show ITGA2 Antibodies) and alpha 4 Yxxphi motifs interact with the endocytic clathrin adaptor, AP2 complex (show AP2B1 Antibodies).
Data show that a small molecule inhibitor of the MYC (show MYC Antibodies) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (show ITGAV Antibodies) and VLA-4-targeted nanotherapy approach.
Collectively, these data suggest a role for alpha4beta7 integrin in HIV infection that is influenced by both viral and host factors including the sequence of the HIV gp120 (show ITIH4 Antibodies) alpha4beta7 binding motif, the cytokine milieu and bacterial vaginosis in the genital tract.
CD49d and CD26 (show DPP4 Antibodies) have independent prognostic value and we suggest its use as a part of routine panel for prognostic stratification of CLL.
Hypermethylation of ITGA4 promoter is increased in inflamed colon tissue.
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
integrin alpha 4
, CD49 antigen-like family member D
, LPAM subunit alpha
, VLA-4 receptor, alpha 4 subunit
, VLA-4 subunit alpha
, integrin alpha-4
, integrin alpha-IV
, lymphocyte Peyer patch adhesion molecules subunit alpha
, 269C wild type
, antigen CD49D, alpha-4 subunit of VLA-4 receptor
, integrin alpha-4 subunit
, very late activation protein 4 receptor, alpha 4 subunit