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ITAGV encodes integrin alpha chain V. Additionally we are shipping CD51 Proteins (13) and CD51 Kits (11) and many more products for this protein.
Showing 10 out of 370 products:
Human Monoclonal CD51 Primary Antibody for FACS - ABIN2660879
Nesbitt, Nesbit, Helfrich, Horton: Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins. in The Journal of biological chemistry 1993
Show all 6 references for ABIN2660879
Human Polyclonal CD51 Primary Antibody for FACS, IF (p) - ABIN674784
Mondal, Barui, Chaudhuri: The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor. in Biomaterials 2013
Show all 4 references for ABIN674784
Human Polyclonal CD51 Primary Antibody for FACS, ICC - ABIN4900194
Rhein, Brouillette, Schaack, Chiorini, Maury: Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry. in Journal of virology 2016
Show all 3 references for ABIN4900194
Human Monoclonal CD51 Primary Antibody for EIA, IF - ABIN1106450
Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006
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Chicken Monoclonal CD51 Primary Antibody for FACS, IP - ABIN319776
Simpson, Horton: Expression of the vitronectin receptor during embryonic development; an immunohistological study of the ontogeny of the osteoclast in the rabbit. in British journal of experimental pathology 1989
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Dog (Canine) Monoclonal CD51 Primary Antibody for IF, WB - ABIN968314
Bodary, McLean: The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. in The Journal of biological chemistry 1990
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Human Monoclonal CD51 Primary Antibody for FACS, IP - ABIN263013
Grzeszkiewicz, Kirschling, Chen, Lau: CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain. in The Journal of biological chemistry 2001
Show all 2 references for ABIN263013
Human Monoclonal CD51 Primary Antibody for FACS - ABIN4898649
Chang, Lo, Juan, Chang, Chuang: Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells. in PLoS ONE 2012
Show all 2 references for ABIN4898649
Human Polyclonal CD51 Primary Antibody for IF (p), IHC (p) - ABIN678983
Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. in Stem cells (Dayton, Ohio) 2016
Suggest that alphavbeta3 integrin plays an important role in coordinating hepatocyte division during liver regeneration after partial hepatectomy via crosstalk with fibrin ECM (show MMRN1 Antibodies).
Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Antibodies).
This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.
These data support the hypothesis that IL-1beta (show IL1B Antibodies) was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1 (show TGFB1 Antibodies).
Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.
These results suggest that phloretin was an inhibitor of actin podosomes and sealing zone, disrupting alpha5beta3 integrin-c-Src-Pyk2/Syk signaling pathway for the regulation of actin cytoskeletal organization in osteoclasts.
TN-C (show TNC Antibodies) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3/FAK (show PTK2 Antibodies)-Src (show SRC Antibodies)/NF-kappaB (show NFKB1 Antibodies), resulting in increased fibrosis.
Lung histology revealed aberrant elastin (show ELN Antibodies) production and impaired lung septation in oxygen-exposed lungs, while tropoelastin (show ELN Antibodies), integrin alphav, fibulin-1 (show FBLN1 Antibodies), fibulin-2 (show FBLN2 Antibodies) and fibulin-4 (show FBLN4 Antibodies) gene expression were elevated.
Knock-in mice expressing a CCN1 (show CCNA2 Antibodies) mutant that is unable to bind alphavbeta5/alphavbeta3 were impaired in ductular reaction. CCN1 (show CCNA2 Antibodies), acting through its alphav beta3/alphav beta5 binding site, is critical for survival after bile duct ligation.
These results suggest that integrin alphavbeta3 mediates the synergetic regulation of Cbfa1 (show RUNX2 Antibodies) transcription activity by gravity and IGF-1 (show IGF1 Antibodies) via PI3K signaling.
The results implied that these five single nucleotide polymorphisms in the integrin alphavbeta3 gene were not associated with hemorrhagic fever with renal syndrome susceptibility or severity in Han Chinese individuals in Hubei Province.
Gastric cancer patients who were both alphavbeta6 and MMP-9 (show MMP9 Antibodies) positive had a shorter overall survival.
The results of this study demonstrate that molecular dynamics of alphav integrin-GFP can be imaged in lung metastasis, which will allow further understanding of the role of alphav integrin in this process.
Periostin (show POSTN Antibodies) expression in human periodontal ligament fibroblasts promotes the migration of human mesenchymal stem cells through the alphavbeta3 integrin/FAK (show PTK2 Antibodies)/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway in vitro.
Results showed that CD51 expression in pancreatic cancer stroma is associated with enhanced tumor malignancy.
endothelial VEGFR-2 appeared to be slightly superior to endothelial alpha v ss 3 for differentiating benign from cancerous lesions.
PDI-mediated disulfide bond exchange plays a pivotal role in the post-ligation phase of alphaIIbbeta3-mediated adhesion to fibrinogen, while this step in alphavbeta3-mediated adhesion is independent of disulfide exchange
Identify integrin alphavbeta3 as a receptor ofNC1 domain of collagen XIX. NC1(XIX) inhibits the FAK (show PTK2 Antibodies)/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway, by decreasing the phosphorylation and activity of the major proteins involved in this pathway.
ERK (show EPHB2 Antibodies)-mediated transcription regulation of the alphav monomer is regulated by T3. Thyroid hormones are potent alphavbeta3-ligands, driving ovarian cancer cell proliferation.
The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.
Inhibition of integrin alphavbeta3 prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.
These results demonstrate the critical role of the RhoA (show RHOA Antibodies)/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
, alphav integrin
, integrin alpha V
, integrin alpha-V
, vitronectin receptor alpha polypeptide (VNRA)
, vitronectin receptor subunit alpha
, antigen identified by monoclonal antibody L230
, integrin alphaVbeta3
, Dnmt3l-ps1 pseudogene
, alphaV integrin
, integrin alpha v
, vitronectin receptor alpha subunit
, integrin alpha V subunit