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The protein encoded by ILKAP is a protein serine/threonine phosphatase of the PP2C family. Additionally we are shipping Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C Antibodies (82) and Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C Kits (4) and many more products for this protein.
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Human ILKAP Protein expressed in Human Cells - ABIN2005305
Leung-Hagesteijn, Mahendra, Naruszewicz, Hannigan: Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1. in The EMBO journal 2001
our data suggest an essential role of PINCH1 (show LIMS1 Proteins), ILK (show ILK Proteins) and ILKAP for the radioresistance of p53 (show TP53 Proteins)-wildtype glioblastoma multiforme cells
The expression of ILKAP was considerably lower in eutopic and ectopic endometrial samples from women with endometriosis than in control endometrium. Expression varied depending on the phase of the menstrual cycle.
Data show involvement of ANXA5 (show ANXA5 Proteins) and ILKAP in susceptibility to malignant melanoma
ILKAP is a nuclear protein (show RDBP Proteins) that regulates cell survival and apoptosis through the regulation of RSK2 (show RPS6KA3 Proteins) signaling.
these results suggested that palladin (show PALLD Proteins) played a specific role in modulating the subcellular localization of the cytoplasmic ILKAP and promoting the ILKAP-induced apoptosis.
These studies demonstrate the importance for keratinocyte proliferation of ILK (show ILK Proteins) regulation through changes in its subcellular localization, and establish ILKAP and CRM1 (show XPO1 Proteins) as pivotal modulators of ILK (show ILK Proteins) subcellular distribution and activity in these cells.
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
integrin-linked kinase-associated serine/threonine phosphatase 2C
, integrin-linked kinase-associated protein phosphatase 2C
, integrin-linked kinase-associated serine/threonine phosphatase 2C-like
, integrin-linked kinase-associated serine/threonine phosphatase
, integrin-linked kinase associated phosphatase
, protein phosphatase 2c, delta isozyme
, protein phosphatase 2C