You are viewing an incomplete version of our website. Please click to reload the website as full version.

Intercellular Adhesion Molecule 4 Proteins (ICAM4)

ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. Additionally we are shipping ICAM4 Antibodies (50) and ICAM4 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ICAM4 3386 Q14773
ICAM4 78369 Q9ERM2
ICAM4 298702  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ICAM4 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,541.00
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details

ICAM4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced ICAM4 Proteins

  1. Human ICAM4 Protein expressed in Human Cells - ABIN2005647 : Bhalla, Chugh, Mehrotra, Rathore, Tousif, Prakash Dwivedi, Prakash, Kumar Samuchiwal, Kumar, Kumar Singh, Ghanwat, Kumar, Das, Mohmmed, Malhotra, Ranganathan: Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparum. in Nature communications 2015 (PubMed)

More Proteins for Intercellular Adhesion Molecule 4 (ICAM4) Interaction Partners

Human Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM (show BCAM Proteins), ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.

  2. ICAM-1 (show ICAM1 Proteins) and ICAM-4 play roles in host cell invasion by M. tuberculosis and P. falciparum, respectively.

  3. Seven variant ICAM4 alleles were found, distinct from the wild-type ICAM4 allele (GenBank KF712272), known as LW*05 and encoding LW(a) .

  4. Data from differentiating cultured erythroid precursor cells suggest that RhAG (Rh-associated glycoprotein (show RHAG Proteins)) knockdown abolishes Rh blood group (show DARC Proteins) expression (ICAM4; RhoD [ras homolog family member D]; CD47 Rh-related antigen (show CD47 Proteins)) in erythroid cells.

  5. Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.

  6. In a transgenic mouse model of sickle cell disease ICAM-4 is implicated in abnormal adhesiveness of erythrocytes to endothelium.

  7. ICAM-4 as the first red blood cells protein ligand of platelets that may have relevant physiological significance

  8. binds to the I domains of the CD11a (show ITGAL Proteins)/CD18 (show ITGB2 Proteins) and CD11b/CD18 (show ITGAM Proteins) leukocyte integrins

  9. 12 single amino-acid changes in ICAM4 affected the interaction of ICAM-4 with alpha(V) integrins

  10. Different integrins bind to different but partly overlapping sites on ICAM4, and ICAM4 may accommodate multiple integrin receptors present on leukocytes, platelets and endothelial cells.

Mouse (Murine) Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. A novel second splice cDNA encodes an ICAM-4 isoform lacking the membrane-spanning domain. Erythroblasts express both isoforms. This new isoform, ICAM (show ICAM1 Proteins)-4S, may modulate membrane-associated ICAM-4 binding & regulate erythroblast molecular attachments.

  2. ICAM-4 is critical in erythroblastic island formation via ICAM-4/alpha(V) adhesion

ICAM4 Protein Profile

Protein Summary

This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100\; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ICAM4

  • Body weight (25 weeks) (WT25)
  • intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4)
  • intercellular adhesion molecule 4-like (LOC100516594)
  • intercellular adhesion molecule 4, Landsteiner-Wiener blood group (Icam4)
  • 1810015M19Rik protein
  • Cd242 protein
  • ICAM-4 protein
  • ICAM4 protein
  • LW protein

Protein level used designations for ICAM4

CD242 antigen , LW blood group protein , Landsteiner-Wiener blood group antigen a , Landsteiner-Wiener blood group glycoprotein , intercellular adhesion molecule 4 , intercellular adhesion molecule 4 (LW blood group) , Landsteiner-Wiener blood group protein , intercellular adhesion molecule 4, Landsteiner-Wiener blood group , LW glycoprotein

GENE ID SPECIES
449199 Sus scrofa
3386 Homo sapiens
611265 Canis lupus familiaris
514873 Bos taurus
455698 Pan troglodytes
100516594 Sus scrofa
78369 Mus musculus
298702 Rattus norvegicus
Selected quality suppliers for ICAM4 Proteins (ICAM4)
Did you look for something else?