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Interferon, gamma-Inducible Protein 30 Proteins (IFI30)

The protein encoded by IFI30 is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. Additionally we are shipping IFI30 Antibodies (41) and IFI30 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFI30 65972 Q9ESY9
IFI30 290644 Q499T2
IFI30 10437 P13284
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Top IFI30 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,409.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,410.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,464.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

IFI30 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , , ,
,

Top referenced IFI30 Proteins

  1. Human IFI30 Protein expressed in Escherichia coli (E. coli) - ABIN1098216 : Arunachalam, Phan, Geuze, Cresswell: Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT). in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 references for ABIN1098216

More Proteins for Interferon, gamma-Inducible Protein 30 (IFI30) Interaction Partners

Zebrafish Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. GILT expression is up-regulated in spleen and kidney after immunization with LPS (show IRF6 Proteins) although it also is constitutively expressed in heart, liver, muscle and intestine, suggesting that GILT may be involved in the immune response to bacterial challenge.

Mouse (Murine) Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. GILT has a role in maintaining cysteine cathepsin proteolytic efficiency in phagosomes

  2. These results show that wild-type mouse fibroblasts are relatively resistant and GILT(-/-)mouse fibroblasts are susceptible to Dengue virus 2 entry and replication.

  3. Data indicate that in the absence of Gamma-interferon-inducible lysosomal thiol reductase (GIL (show AQP3 Proteins), CD4 (show CD4 Proteins)-positive T cell responses to major house dust mite allergen Der (show GDF3 Proteins) p 1 are significantly reduced.

  4. GILT has a critical role in regulating CD4 (show CD4 Proteins)(+) T-cell tolerance to an endogenous skin-restricted antigen relevant to controlling autoimmunity and generating effective immunotherapy for melanoma.

  5. We showed that STAT1 (show STAT1 Proteins) interacts with the GILT promoter, even in the absence of IFN-gamma (show IFNG Proteins), and that STAT1 (show STAT1 Proteins) represses GILT expression.

  6. GILT has limited yet unexpected effect on self-peptide species presented by major histocompatibility complex class II antigens.

  7. study shows GILT facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8 (show CD8A Proteins)+ T cells or cross-presentation;initiation of gB-specific CD8 (show CD8A Proteins)+ T cell response during HSV-1 infection or cross-priming is GILT-dependent

  8. the thiol reductase activity of GILT is its essential function in MHC class II-restricted Ag processing

  9. GILT appears to have a fundamental role in cellular proliferation mediated through its influence on SOD2 (show SOD2 Proteins) protein activity and expression.

  10. findings show that endogenously produced peptide-IgG is processed by transduced splenic B cells in the lysosomes/endosomes in a GILT-dependent manner, and this endocytic processing pathway is essential for generating tolerogenic B cells

Human Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. The lysosomal thiol reductase GILT expressed by antigen-presenting cells has diverse cellular and organismal functions. (Review)

  2. this review discusses recent studies that have advanced our understanding of the role of GILT in antigen processing and revealed surprising new functions for the enzyme.[review]

  3. Single nucleotide polymorphism of the interferon-gamma-inducible protein 30 gene is associated with hyperglycemia in severely obese individuals.

  4. GILT is required for efficient histocompatiblity class II-restricted processing of melanoma antigen tyrosinase-related protein 1 epitope in vitro and accelerates the onset of vitiligo in TRP1-specific T-cell receptor transgenic mice.

  5. Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes.

  6. Role of the C-terminal propeptide in the activity and maturation of gamma -interferon-inducible lysosomal thiol reductase (GILT).

  7. GILT-expressing melanoma cells could prove to be very promising for direct antigen presentation and CD4 (show CD4 Proteins)+ T cell recognition

  8. studied gene expression profile of brain lesions of a patient with Neuromyelitis optica by using DNA microarray; found marked up-regulation of interferon gamma-inducible protein 30 (IFI30), CD163 (show CD163 Proteins), and secreted phosphoprotein 1 (SPP1 (show SPP1 Proteins), osteopontin (show SPP1 Proteins))

Pig (Porcine) Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. The cloning and characterization of porcine gamma-interferon-inducible lysosomal thiol reductase (GILT) are reported.

IFI30 Protein Profile

Protein Summary

The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

Gene names and symbols associated with IFI30

  • interferon gamma inducible protein 30 (ifi30)
  • interferon, gamma-inducible protein 30 (IFI30)
  • interferon, gamma-inducible protein 30 (ifi30)
  • interferon gamma inducible protein 30 (LOC100304719)
  • interferon gamma inducible protein 30 (Ifi30)
  • GILT protein
  • IFI-30 protein
  • IP30 protein
  • wu:fb12b04 protein
  • zgc:101752 protein

Protein level used designations for IFI30

LycGILT , gamma-interferon-inducible lysosomal thiol reductase , interferon, gamma-inducible protein 30 , interferon gamma inducible protein 30 , gamma-interferon-inducible protein IP-30 , lysosomal thio reductase IP30 , lysosomal thiol reductase IP30 , interferon gamma-inducible protein 30 preproprotein , legumaturain , gamma-inducible protein 30 , gamma-interferon-inducible-lysosomal thiol reductase

GENE ID SPECIES
336503 Danio rerio
420129 Gallus gallus
549950 Xenopus (Silurana) tropicalis
100304719 Ictalurus punctatus
65972 Mus musculus
290644 Rattus norvegicus
10437 Homo sapiens
615930 Bos taurus
100174943 Sus scrofa
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