Interferon Regulatory Factor 2 Proteins (IRF2)

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. Additionally we are shipping Interferon Regulatory Factor 2 Antibodies (139) and Interferon Regulatory Factor 2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IRF2 3660 P14316
IRF2 16363 P23906
Rat IRF2 IRF2 290749  
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Top Interferon Regulatory Factor 2 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$375.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$460.85
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,946.17
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$467.86
Details

IRF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , , ,
Mouse (Murine) ,

More Proteins for Interferon Regulatory Factor 2 (IRF2) Interaction Partners

Human Interferon Regulatory Factor 2 (IRF2) interaction partners

  1. In a genome wide are study to identify acute kidney injury risk in critically ill patients, the locus on chromosome 4, located 150 kb upstream of IRF2 was identified to regulate immunity pathways related to kidney disease risk gene APOL1 (show APOL1 Proteins). Disruption of IRF-2 has been found to up-regulate the inflammatory response to infection.

  2. Study shows that IRF2 knockdown inhibits growth, colony formation of OCI/AML-2 (show RUNX3 Proteins), OCI/AML-3 (show RUNX2 Proteins), and THP-1 cells. In addition, IRF2 knockdown induces apoptosis of acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) cells by regulating apoptotic effectors. Further mechanism analysis shows that INPP4B (show INPP4B Proteins) contributes to the effects of IRF2 on apoptosis and growth of AML (show RUNX1 Proteins) cells. Thus, IRF2 serves as an important regulator in AML (show RUNX1 Proteins) by targeting INPP4B (show INPP4B Proteins).

  3. miR (show MLXIP Proteins)-450 targets IRF2 and thus supresses lung cancer cell proliferation and invasion.

  4. It might play as a tumor suppressor by regulating P53 (show TP53 Proteins) signaling in gastric cancer.

  5. the association of IRF2 with susceptibility to systemic lupus erythematosus

  6. Data suggest that interferon (show IFNA Proteins) regulatory factors 1 and 2 (IRF1 (show IRF1 Proteins) and IRF2) may serve as potential targets of therapy.

  7. miR (show MLXIP Proteins)-221 directly inhibits the expression of SOCS3 (show SOCS3 Proteins) and IRF2.

  8. KGF (show FGF7 Proteins) could up-regulate IL-7 (show IL7 Proteins) expression through the STAT1 (show STAT1 Proteins)/IRF-1 (show IRF1 Proteins), IRF-2 signaling pathway, which is a new insight in potential effects of KGF (show FGF7 Proteins) on the intestinal mucosal immune system.

  9. IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (show SPINK1 Proteins)

  10. IRF2 overexpression protects against I/R injury by decreasing IRF1 (show IRF1 Proteins)-dependent injury and may represent a novel therapeutic strategy.

Mouse (Murine) Interferon Regulatory Factor 2 (IRF2) interaction partners

  1. Mysm1 enhanced function of the IRF2 and IRF8 promoters, suggesting that Mysm1 governs the IRFs for hematopoietic stem cell homeostasis.

  2. Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

  3. Chimeric IRF-2 binds with IRF (show TRIM63 Proteins)-E motif and VREbeta but not with VREalpha1.

  4. KGF (show FGF7 Proteins) could up-regulate IL-7 (show IL7 Proteins) expression through the STAT1 (show STAT1 Proteins)/IRF-1 (show IRF1 Proteins), IRF-2 signaling pathway, which is a new insight in potential effects of KGF (show FGF7 Proteins) on the intestinal mucosal immune system.

  5. IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3

  6. These results revealed a multi-faceted role of IRF-2 in the function of B cells, particularly B2 cells, through regulating proliferation in an IFNAR (show IFNAR1 Proteins)-dependent manner and antibody production via up-regulation of Blimp-1 (show PRDM1 Proteins).

  7. In mice doubly deficient forIRF-2 and CD1d (show CD1D Proteins), the overall memory phenotype T cell population is contrastingly enlarged.

  8. IRF2 regulates exocytosis in pancreatic acinar cells; defects in this process might be involved in the early phases of acute pancreatitis.

  9. Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells.

  10. Irf2 has an important role in vitro in the regulation of COX-2 expression by LPS (show TLR4 Proteins).

Interferon Regulatory Factor 2 (IRF2) Protein Profile

Protein Summary

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Gene names and symbols associated with IRF2

  • interferon regulatory factor 2 (IRF2)
  • interferon regulatory factor 2 (Irf2)
  • interferon regulatory factor 2 (irf2)
  • 9830146E22Rik protein
  • AI646973 protein
  • irf-2 protein
  • irf2b protein
  • zgc:103451 protein

Protein level used designations for IRF2

regulatory factor 2 , interferon responsive factor 2 , interferon regulatory factor 2b

GENE ID SPECIES
3660 Homo sapiens
396115 Gallus gallus
475633 Canis lupus familiaris
337916 Bos taurus
16363 Mus musculus
290749 Rattus norvegicus
494071 Danio rerio
495990 Xenopus laevis
100621620 Sus scrofa
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