You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Interferon Regulatory Factor 8 (IRF8) Antibodies

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Additionally we are shipping IRF8 Proteins (7) and IRF8 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IRF8 3394 Q02556
IRF8 15900 P23611
IRF8 292060  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-IRF8 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-IRF8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of anti-IRF8 Antibody (C-term) (ABIN389336) in HL60 cell line lysates (35 µg/lane). IRF8 (arrow) was detected using the purified polyclonal antibody. IRF8 Antibody (C-term) (ABIN389336) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of anti-IRF8 Antibody (Center) (ABIN389337) in Jurkat cell line lysates (35 µg/lane). IRF8 (arrow) was detected using the purified polyclonal antibody. IRF8 Antibody (Center) (ABIN389337) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184813 staining (1µg/ml) of K562 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of IRF8 in human thymus tissue lysate with AP30451PU-N IRF8 antibody at 1μg/ml in (A) the presence and (B) absence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details

IRF8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
, ,
,
, , , , , ,
Mouse (Murine) , ,
, ,
,
, ,
Rat (Rattus)
,

Top referenced anti-IRF8 Antibodies

  1. Human Polyclonal IRF8 Primary Antibody for IHC (p), WB - ABIN303274 : Weisz, Marx, Sharf, Appella, Driggers, Ozato, Levi: Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes. in The Journal of biological chemistry 1993 (PubMed)
    Show all 3 references for ABIN303274

  2. Human Polyclonal IRF8 Primary Antibody for FACS, WB - ABIN389337 : McGough, Yang, Huang, Georgi, Hewitt, Röcken, Tänzer, Ebert, Liu: DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. in Molecular cancer research : MCR 2008 (PubMed)
    Show all 3 references for ABIN389337

  3. Human Polyclonal IRF8 Primary Antibody for FACS, WB - ABIN389336 : Tshuikina, Jernberg-Wiklund, Nilsson, Oberg: Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. in Experimental hematology 2008 (PubMed)
    Show all 3 references for ABIN389336

  4. Dog (Canine) Polyclonal IRF8 Primary Antibody for IHC, WB - ABIN2792612 : Yang, Thangaraju, Greeneltch, Browning, Schoenlein, Tamura, Ozato, Ganapathy, Abrams, Liu: Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. in Cancer research 2007 (PubMed)
    Show all 2 references for ABIN2792612

  5. Human Polyclonal IRF8 Primary Antibody for EIA, WB - ABIN500062 : Malmgaard: Induction and regulation of IFNs during viral infections. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 (PubMed)

  6. Human Polyclonal IRF8 Primary Antibody for WB - ABIN2777225 : Ye, Wang, Wang, Wang, Song, Hou, Zhou, Li, Ho: CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes. in Hepatology (Baltimore, Md.) 2009 (PubMed)

More Antibodies against IRF8 Interaction Partners

Zebrafish Interferon Regulatory Factor 8 (IRF8) interaction partners

  1. Study reveals that specification of all macrophages requires irf8 during an early period of zebrafish hematopoiesis but not during the adult-phase. Also, Irf8 seems to have essential roles in host defense as well.

  2. Irf8 is a critical determinant for neutrophil versus macrophage fate choice during zebrafish primitive myelopoiesis.

Human Interferon Regulatory Factor 8 (IRF8) interaction partners

  1. IRF5 (show IRF5 Antibodies) and IRF8, two transcription factors with opposing functions, control TLR9 (show TLR9 Antibodies) signaling in human plasmacytoid dendritic cells.

  2. cytarabine-induced upregulation of the IRF8 in leukemic cells involves increased levels of ZNF224 (show ZNF224 Antibodies), which can counteract the repressive activity of WT1 (show WT1 Antibodies) on the IRF8-promoter

  3. Expression of WT1and IRF8 showed a moderate inverse correlation in acute myeloid leukemia (show BCL11A Antibodies) patients. WT1 (show WT1 Antibodies) can be used as an minimal residual disease marker, especially in patients without recurrent genetic abnormalities.

  4. Results show that IRF8 is a possible genetic variant associated with the development of HT and production of thyroid antibody

  5. The IRF8 gene variant influenced the interaction between IRF8 and NF-kappaB (show NFKB1 Antibodies) and thus susceptibility to systemic sclerosis.

  6. This article provides an overview of recent advances in our understanding of the role of IRF8 in myelopoiesis and related diseases. [review]

  7. This study demonstrated that the Polymorphism, Single Nucleotide of IRF8 is associated with multiple sclerosis in woman in Russia.

  8. gene variants in IRF5 (show IRF5 Antibodies), IRF8 and GPC5 (show GPC5 Antibodies) were not associated with risk of relapse or disease progression in multiple sclerosis

  9. Irf8 forms a negative feedback loop with Cebpb (show CEBPB Antibodies), a monocyte-derived DC epigenetic fate-determining transcription factor.

  10. MN1 (show MN1 Antibodies) prevents activation of the immune response pathway, and suggest restoration of IRF8 signaling as therapeutic target in AML (show RUNX1 Antibodies)

Mouse (Murine) Interferon Regulatory Factor 8 (IRF8) interaction partners

  1. direct the expression of a set of genes, the IRF8/IRF1 (show IRF1 Antibodies) regulome, that play critical roles in host inflammatory and antimicrobial defenses in mouse models of neuroinflammation and of pulmonary tuberculosis, respectively

  2. we identified IRF8 target genes in gastric epithelial cells, providing a detailed understanding of how IRF8 functions in gastric mucosal innate immunity

  3. results suggest that impaired Icsbp expression enhances leukemogenesis by deregulating processes that normally limit granulocyte expansion during the innate immune response.

  4. variation in IRF4 (show IRF4 Antibodies) or IRF8 levels resulting from genetic polymorphisms or environmental cues will govern tissue dendritic cells numbers and regulate the magnitude of their functional responses.

  5. Data indicate that interferon regulatory factor-8 (IRF8) regulates tumor behavior in an matrix metalloproteinase 3 (MMP3 (show MMP3 Antibodies))-dependent manner.

  6. Data indicate that interferon (show IFNA Antibodies) regulatory factors IRF4 (show IRF4 Antibodies) and IRF8 control distinct activated B cell states.

  7. dendritic cells from mice with CD11c (show ITGAX Antibodies)-specific constitutive b-catenin activation upregulated IRF8 through targeting of the Irf8 promoter, leading to in vivo expansion of IRF8-dependent CD8alpha+, plasmacytoid, and CD103 (show ITGAE Antibodies)+ CD11b2 dendritic cells.

  8. IRF8 not only bestows monocyte and DC differentiation potential upon mononuclear phagocyte progenitors but also restrains these progenitors from differentiating into neutrophils in a process involving C-EBPalpha (show CEBPA Antibodies)

  9. Loss of IRF8 in T Cells Exacerbates Uveitis, Whereas Irf8 Deletion in the Retina Confers Protection

  10. Data show that IRF8 directly interacts with NFATc1 (show NFATC1 Antibodies) to prevent NFATc1 (show NFATC1 Antibodies) translocation and thus inhibits the hypertrophic response.

IRF8 Antigen Profile

Protein Summary

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Gene names and symbols associated with IRF8

  • interferon regulatory factor 8 (irf8) antibody
  • interferon regulatory factor 8 (IRF8) antibody
  • interferon regulatory factor 8 (LOC100350620) antibody
  • interferon regulatory factor 8 (Irf8) antibody
  • AI893568 antibody
  • DKFZp469B0320 antibody
  • H-ICSBP antibody
  • ICSBP antibody
  • Icsbp1 antibody
  • IRF-8 antibody
  • IRF8 antibody
  • MGC140338 antibody
  • Myls antibody
  • zgc:92252 antibody

Protein level used designations for IRF8

DKEYP-77B5.1 , interferon regulatory factor 8 , interferon regulatory factor 8-like , interferon consensus sequence binding protein 1 , interferon consensus sequence-binding protein , transcription factor ICSBP , IRF-8 , interferon consensus sequence binding protein

GENE ID SPECIES
436895 Danio rerio
454294 Pan troglodytes
489673 Canis lupus familiaris
614909 Bos taurus
693933 Macaca mulatta
100018105 Monodelphis domestica
100056218 Equus caballus
100173775 Pongo abelii
100350620 Oryctolagus cuniculus
100405221 Callithrix jacchus
100469809 Ailuropoda melanoleuca
100598495 Nomascus leucogenys
3394 Homo sapiens
446986 Xenopus laevis
15900 Mus musculus
292060 Rattus norvegicus
396385 Gallus gallus
Selected quality suppliers for anti-IRF8 (IRF8) Antibodies
Did you look for something else?