IRF8 Products
(Interferon Regulatory Factor 8 (IRF8))
Categories
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008].
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Featured IRF8 Categories
IRF8 Antibodies
High quality antibodies with extensive validation data.
IRF8 ELISA Kits
Reliable ELISA kits for a wide range of species.
IRF8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRF8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7444418
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN2792611
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7444517
Quantity
100 μL
Datasheet
Datasheet
Recommended IRF8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967758
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1138463
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1138462
Quantity
96 tests
Datasheet
Datasheet
Recommended IRF8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308098
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308100
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3082238
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IRF8 products
: "The Expression of Interferon Regulatory Factor 8 in Human Periapical Lesions." in: Journal of endodontics, Vol. 44, Issue 8, pp. 1276-1282, (2019) (PubMed).: "Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury." in: Journal of neurochemistry, Vol. 129, Issue 6, pp. 988-1001, (2014) (PubMed).
: "IFN-? activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production." in: Biochemical pharmacology, Vol. 80, Issue 12, pp. 2074-86, (2010) (PubMed).
: "CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 3, pp. 753-62, (2009) (PubMed).
: "Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6820-7, (2004) (PubMed).
: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).
: "Induction and regulation of IFNs during viral infections." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 24, Issue 8, pp. 439-54, (2004) (PubMed).
: "The Bcl-2 family: roles in cell survival and oncogenesis." in: Oncogene, Vol. 22, Issue 53, pp. 8590-607, (2003) (PubMed).
: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).
: "bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria." in: Development (Cambridge, England), Vol. 120, Issue 10, pp. 3033-42, (1995) (PubMed).
Synonyms and alternative names related to IRF8
interferon regulatory factor 8 (irf8), interferon regulatory factor 8 (IRF8), interferon regulatory factor 8 L homeolog (irf8.L), interferon regulatory factor 8 (Irf8), AI893568, DKFZp469B0320, H-ICSBP, ICSBP, ICSBP1, icsbp1, Icsbp1, IRF-8, IRF8, MGC140338, Myls, zgc:92252Protein level used designations for IRF8
- DKEYP-77B5.1
- interferon regulatory factor 8
- interferon regulatory factor 8-like
- interferon consensus sequence binding protein 1
- interferon consensus sequence-binding protein
- transcription factor ICSBP
- IRF-8
- interferon consensus sequence binding protein
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