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IFIT2 encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Additionally we are shipping Interferon-Induced Protein with Tetratricopeptide Repeats 2 Proteins (5) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal IFIT2 Primary Antibody for WB - ABIN2773795
Terenzi, Hui, Merrick, Sen: Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56. in The Journal of biological chemistry 2006
Human Polyclonal IFIT2 Primary Antibody for IF, WB - ABIN516834
Lee, Li, Gretz, Gebert, Dihlmann: Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers. in Oncogene 2012
These results indicate that high Sendai virus replication in the lungs of infected Ifit2(-/-) mice cooperates with elevated IFN-beta (show IFNB1 Antibodies) induction to cause disease.
Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.
Ifit2 is a positive regulator of IFN-alpha (show IFNA Antibodies)/beta expression during mouse hepatitis virus induced encephalitis.
IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS (show TLR4 Antibodies))-induced TNF-alpha (show TNF Antibodies) secretion and LPS (show TLR4 Antibodies)-induced endotoxin shock.
These results suggest that Ifit2 restricts West Nile virus infection and pathogenesis in different tissues in a cell type-specific manner.
results indicate that in the brain, but not in other organs, Ifit2 is a major mediator of IFN's protective effect against VSV
Inhibitor of kappaB kinase epsilon (IKK(epsilon (show IKBKE Antibodies))), STAT1 (show STAT1 Antibodies), and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.
Our findings provide the first evidence of a differential pattern of expression of ISG54 and ISG56 (show IFIT1 Antibodies) genes by IFN-alpha (show IFNA Antibodies) and IFN-beta (show IFNB1 Antibodies).
IFIT-2 may affect selectively LPS (show TLR4 Antibodies) induced protein expression probably by regulation at different posttranscriptional levels
IFIT2/GARG39 was identified as a microtubule-associated protein (show SPAG5 Antibodies) enriched in the mitotic spindle of mouse NIH3T3 and B16F10 melanoma cells.
Data show that interferon (show IFNA Antibodies)-induced proteins with tetratricopeptide repeats 1 and 2 (IFIT1 (show IFIT1 Antibodies) and IFIT2) contribute to the regulation of hepatitis B virus (HBV) replication, likely at both transcriptional and posttranscriptional steps.
Data shows that IFIT2 expression is downregulated in adenocarcinoma of gastric esophageal junction cells; its ectopic expression leads to cell apoptosis, suggesting its role as a tumor suppressor.
1p31 SFRS11 (show SRSF11 Antibodies) v
IFIT2, a protein responsible for interferon (show IFNA Antibodies) stimulation, may prevent oral squamous cell carcinoma (OSCC) metastasis and serve as a valuable prognostic marker.
ISG54 binds specifically to some RNAs, such as adenylate uridylate (AU)-rich RNAs, with or without 5' triphosphorylation.
The expression of OASL (show OASL Antibodies) and IFIT2 was significantly higher in SLE patients than in controls.
role of ISG54 in the induction of apoptosis via a mitochondrial pathway shedding new light on the mechanism by which IFN elicits anti-viral and anti-cancer effects
The expression of interferon (show IFNA Antibodies)-induced genes IFI-54K and IFI-56K (show IFIT1 Antibodies) in the infected cells was found to increase 50-100-fold
We observed that, although double-stranded RNA or Sendai virus infection induced the two genes with similar kinetics, their induction kinetics in response to interferon-beta (show IFNB1 Antibodies) were quite different.
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.
interferon-induced protein with tetratricopeptide repeats 2
, glucocorticoid-attenuated response gene 39 protein
, interferon-induced 54 kDa protein
, Interferon, alpha-inducible protein (MW 54kD)
, interferon-induced protein 54
, SR splicing factor 11
, arginine-rich 54 kDa nuclear protein
, splicing factor p54
, splicing factor, arginine/serine-rich 11