anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) Antibodies

IFIT2 encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Additionally we are shipping Interferon-Induced Protein with Tetratricopeptide Repeats 2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IFIT2 3433 P09913
IFIT2 294091  
IFIT2 15958 Q64112
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: IFIT2 Antibody [NBP1-31164] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: IFIT2 protein stained by IFIT2 antibody [N1], N-term diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody diluted at 1:10000. Blue: Hoechst 33342 staining. Immunocytochemistry/Immunofluorescence: IFIT2 Antibody [NBP1-31164] - Analysis of HeLa, using IFIT2 antibody at 1:200 dilution. 100 μL Log in to see 7 to 9 Days
$473.81
Details
Human Rabbit Un-conjugated WB Western Blot: IFIT2 Antibody [NBP2-15180] - Analysis of IFIT2 in human K562 lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse RAW lysate probed with 4 ug/ml of IFIT2 antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test. 0.1 mg Log in to see 7 to 9 Days
$343.88
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: IFIT2 Antibody [NBP1-85617] - Immunofluorescent staining of human cell line U-2 OS shows positivity in vesicles. Immunohistochemistry-Paraffin: IFIT2 Antibody [NBP1-85617] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB IFIT2 Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IFIT2 antibody detected the IFIT2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of IFIT2 expression in transfected 293T cell line by IFIT2 MaxPab polyclonal antibody.<br><br>Lane 1: IFIT2 transfected lysate(56.20 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to IFIT2 on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Log in to see 11 to 12 Days
$418.57
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$240.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using IFIT2 antibody. 100 μL Log in to see 16 Days
$323.13
Details

IFIT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , , , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , , , ,

Top referenced anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 Antibodies

  1. Human Polyclonal IFIT2 Primary Antibody for ICC, IF - ABIN441199 : Baril, Es-Saad, Chatel-Chaix, Fink, Pham, Raymond, Audette, Guenier, Duchaine, Servant, Bilodeau, Cohen, Grandvaux, Lamarre: Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses. in PLoS pathogens 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal IFIT2 Primary Antibody for IF, WB - ABIN516834 : Lee, Li, Gretz, Gebert, Dihlmann: Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers. in Oncogene 2012 (PubMed)

  3. Human Polyclonal IFIT2 Primary Antibody for WB - ABIN2773795 : Terenzi, Hui, Merrick, Sen: Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56. in The Journal of biological chemistry 2006 (PubMed)

  4. Human Polyclonal IFIT2 Primary Antibody for ICC, IF - ABIN4321070 : Feng, Wang, Ma, Yang, Liang, Zhang, Song, Li, Liu, Fan, Gao: MicroRNA-645, up-regulated in human adencarcinoma of gastric esophageal junction, inhibits apoptosis by targeting tumor suppressor IFIT2. in BMC cancer 2014 (PubMed)

  5. Human Polyclonal IFIT2 Primary Antibody for WB - ABIN4321072 : Doiron, Goyon, Coyaud, Rajapakse, Raught, McBride: The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. in Scientific reports 2017 (PubMed)

More Antibodies against Interferon-Induced Protein with Tetratricopeptide Repeats 2 Interaction Partners

Mouse (Murine) Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) interaction partners

  1. Ifit2 exerts its antiviral effect mainly at the level of viral replication, as opposed to functioning as a mechanism that restricts viral entry/egress or transports rabies virus particles through axons.

  2. the mechanism for the observed differential induction of the mouse Ifit1 (show IFIT1 Antibodies), Ifit2, and Ifit3 genes in B cells and demonstrated that the repressive effect of the transcription factor interferon regulatory factor 8 (IRF8 (show IRF8 Antibodies)), which is highly expressed in B cells, played an essential role in this regulation.

  3. These results indicate that high Sendai virus replication in the lungs of infected Ifit2(-/-) mice cooperates with elevated IFN-beta (show IFNB1 Antibodies) induction to cause disease.

  4. Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.

  5. Ifit2 is a positive regulator of IFN-alpha (show IFNA Antibodies)/beta expression during mouse hepatitis virus induced encephalitis.

  6. IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS (show TLR4 Antibodies))-induced TNF-alpha (show TNF Antibodies) secretion and LPS (show TLR4 Antibodies)-induced endotoxin shock.

  7. These results suggest that Ifit2 restricts West Nile virus infection and pathogenesis in different tissues in a cell type-specific manner.

  8. results indicate that in the brain, but not in other organs, Ifit2 is a major mediator of IFN's protective effect against VSV

  9. Inhibitor of kappaB kinase epsilon (IKK(epsilon (show IKBKE Antibodies))), STAT1 (show STAT1 Antibodies), and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

  10. Our findings provide the first evidence of a differential pattern of expression of ISG54 and ISG56 (show IFIT1 Antibodies) genes by IFN-alpha (show IFNA Antibodies) and IFN-beta (show IFNB1 Antibodies).

Human Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) interaction partners

  1. The results of the present study revealed that the inhibition of proteasome activity blocked the degradation of IFIT2 and promoted the aggregation of IFIT2 in the centrosome, which in turn induced cell apoptosis. In short, IFIT2 may be a potential target for cancer therapeutics.

  2. Mechanistic investigations reveal that AJUBA (show AJUBA Antibodies) specifically binds the FERM domain of JAK1 (show JAK1 Antibodies) to dissociate JAK1 (show JAK1 Antibodies) from the IFNgamma recepter, resulting in an inhibition of STAT1 (show STAT1 Antibodies) phosporylation and concomitantly its nuclear translocation. Clinically, the level of AJUBA (show AJUBA Antibodies) in CRC (show CALR Antibodies) specimens is negatively correlated with the levels of IFIT2 and pSTAT1

  3. LINC00161 is an essential regulator in cisplatin-induced apoptosis, and the LINC00161-miR (show MLXIP Antibodies)-645-IFIT2 signalling axis plays an important role in reducing osteosarcoma chemoresistance.

  4. there is a positive feedback loop between phosphorylated STAT1 and ISG56, ISG54 or ISG60.

  5. Data show that interferon (show IFNA Antibodies)-induced proteins with tetratricopeptide repeats 1 and 2 (IFIT1 (show IFIT1 Antibodies) and IFIT2) contribute to the regulation of hepatitis B virus (HBV) replication, likely at both transcriptional and posttranscriptional steps.

  6. Data shows that IFIT2 expression is downregulated in adenocarcinoma of gastric esophageal junction cells; its ectopic expression leads to cell apoptosis, suggesting its role as a tumor suppressor.

  7. 1p31 SFRS11 (show SRSF11 Antibodies) v

  8. IFIT2, a protein responsible for interferon (show IFNA Antibodies) stimulation, may prevent oral squamous cell carcinoma (OSCC) metastasis and serve as a valuable prognostic marker.

  9. ISG54 binds specifically to some RNAs, such as adenylate uridylate (AU)-rich RNAs, with or without 5' triphosphorylation.

  10. Inhibitor of kappaB kinase epsilon (IKK(epsilon (show IKBKE Antibodies))), STAT1 (show STAT1 Antibodies), and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) Antigen Profile

Protein Summary

This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.

Gene names and symbols associated with IFIT2

  • interferon induced protein with tetratricopeptide repeats 2 (IFIT2) antibody
  • interferon-induced protein with tetratricopeptide repeats 2 (Ifit2) antibody
  • interferon-induced protein with tetratricopeptide repeats 15 (ifit15) antibody
  • interferon induced protein with tetratricopeptide repeats 2 (Ifit2) antibody
  • AV302338 antibody
  • cig42 antibody
  • DKFZp468G198 antibody
  • G10P2 antibody
  • GARG-39 antibody
  • IFI-54 antibody
  • IFI-54K antibody
  • Ifi54 antibody
  • IFIT-2 antibody
  • ISG-54 K antibody
  • ISG-54K antibody
  • ISG54 antibody
  • P54 antibody
  • wu:fb58d07 antibody

Protein level used designations for IFIT2

Interferon, alpha-inducible protein (MW 54kD) , interferon-induced 54 kDa protein , interferon-induced protein 54 , interferon-induced protein with tetratricopeptide repeats 2 , GARG-39 , IFI-54K , IFIT-2 , glucocorticoid-attenuated response gene 39 protein

GENE ID SPECIES
3433 Homo sapiens
294091 Rattus norvegicus
322336 Danio rerio
450585 Pan troglodytes
479183 Canis lupus familiaris
527528 Bos taurus
695452 Macaca mulatta
100173024 Pongo abelii
100341555 Oryctolagus cuniculus
100584973 Nomascus leucogenys
15958 Mus musculus
100763118 Cricetulus griseus
Selected quality suppliers for anti-Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) Antibodies
Did you look for something else?