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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Kits (41) and IL27 Proteins (27) and many more products for this protein.
Showing 10 out of 150 products:
Mouse (Murine) Polyclonal IL27 Primary Antibody for WB - ABIN1043831
Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002
Mouse (Murine) Monoclonal IL27 Primary Antibody for WB - ABIN1043836
Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2010
Human Polyclonal IL27 Primary Antibody for EIA, IF - ABIN500000
Hunter: New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. in Nature reviews. Immunology 2005
our findings showed a relationship between the IL-27 2905T/G genotype variant and the decreased susceptibility for developing cervical cancer. The IL-27 2905T/G genotype variant also modified the survival time in cervical cancer patients.
an IL-27/Stat3 (show STAT3 Antibodies) axis induces expression of programmed cell death 1 (show PDCD1 Antibodies) ligands (PD-L1 (show CD274 Antibodies)/2) on infiltrating macrophages in lymphoma
Interleukin-27 rs 153109 Single Nucleotide Polymorphism is associated with responses to therapy in Hepatitis C.
this study shows that IL-27 gene polymorphism is genetic risk factor for systemic lupus erythematosus in the Polish population, and that it predicts disease phenotype
Data indicate that the CC genotype of interleukin 27 (IL-27) single nucleotide polymorphism rs153109 was significantly more prevalent in pre-eclampsia (PE) cases than controls.
IL-27 is a viable candidate biomarker to identify bacterial infection among ED patients and is comparable with PCT (show UROD Antibodies).
The inhibition of Th17 cells by IL-27 is vital for the maintenance of the feto-maternal tolerance and the prevention of lupus, multiple sclerosis, autoimmune uveitis, immune thrombocytopenia and atherosclerosis
Our results showed that the IL-27 2905T/G genotypes were associated with decreased the susceptibility and development of cervical cancer in Chinese Han population.
the genetic polymorphisms of IL-27 rs153109 and rs181206 may be involved in the progression of human cancers and diseases.
Findings demonstrated that IL-27 and IL-27R (show IL27RA Antibodies) were elevated in multiple sclerosis lesions and that local IL-27 can modulate immune properties of astrocytes and infiltrating immune cells
An IL-27/Lag3 (show LAG3 Antibodies) axis enhances Foxp3 (show FOXP3 Antibodies)+ regulatory T cell-suppressive function and therapeutic efficacy.
IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.
These results provide the first evidences that Fli-1 (show FLI1 Antibodies) positively regulates LPS (show TLR4 Antibodies)-induced IL-27 production in macrophages
of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.
Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.
IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 Antibodies)/Pim-1 (show PIM1 Antibodies) signaling pathway.
demonstrate that suppression mediated by interferon (show IFNA Antibodies) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo
Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG Antibodies) and IL-27 production.
demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections
IL-27 regulates enhanced susceptibility to S. aureus pneumonia following influenza infection, potentially through the induction of IL-10 (show IL10 Antibodies) and suppression of IL-17 (show IL17A Antibodies).
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interleukin 27 p28 subunit
, interluekin 27