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Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 Proteins (IRAK1BP1)

Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Additionally we are shipping Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IRAK1BP1 134728 Q5VVH5
IRAK1BP1 65099 Q9ESJ7
IRAK1BP1    
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Top Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Oncorhynchus mykiss His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,638.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IRAK1BP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Oncorhynchus mykiss

More Proteins for Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) Interaction Partners

Human Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) interaction partners

  1. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 (show GORASP1 Proteins) coactivator function of SIMPL.

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) interaction partners

  1. SIMPL functions as a TNFalpha (show TNF Proteins)-dependent p65 (show NFkBP65 Proteins) co-activator by facilitating the recruitment of MED1 (show MBD4 Proteins) to p65 (show NFkBP65 Proteins) containing transcriptional complexes to control the expression of a subset of TNFalpha (show TNF Proteins)-induced genes.

  2. IRAK1BP1 functions through its effects on NF-kappaB (show NFKB1 Proteins) as a molecular switch to bias innate immune pathways toward the resolution of inflammation

  3. Signals transduced through the tumor necrosis factor-alpha-tumor necrosis factor (show TNF Proteins) -receptor I-SIMPL(substrate that interacts with mouse pelle (show IRAK1 Proteins)-like kinase) pathway support hematopoietic progenitor cell survival, growth and differentiation

  4. TNF-alpha (show TNF Proteins) activation of NF-kappaB (show NFKB1 Proteins) dependent-gene expression requires nuclear relocalization of p65 (show NFkBP65 Proteins) as well as nuclear relocalization of SIMPL, generating a TNF-alpha (show TNF Proteins)-specific induction of gene expression.

  5. Hsp70/Hsc70 bind the intrinsically disordered amino-terminal region of SIMPL to stabilize the protein and thereby regulate its activity.

  6. IRAK1BP1 regulates transcription of a specific subset of Toll (show TLR4 Proteins)-like receptor responsive genes, producing an overall antiinflammatory profile

Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) Protein Profile

Protein Summary

Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity).

Gene names and symbols associated with IRAK1BP1

  • interleukin-1 receptor-associated kinase 1 binding protein 1 (LOC100229738)
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (LOC100352510)
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (IRAK1BP1)
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (Irak1bp1)
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (irak1bp1)
  • 4921528N06Rik protein
  • Aabp3 protein
  • AI851240 protein
  • Aip70 protein
  • Simpl protein
  • zgc:112481 protein

Protein level used designations for IRAK1BP1

interleukin-1 receptor-associated kinase 1 binding protein 1 , ActA binding protein 3 , interleukin-1 receptor-associated kinase 1-binding protein 1 , Acta binding protein 3 , Acta-binding protein 70 , Plk-interacting protein , signaling molecule that associates with the mouse pelle-like kinase , interleukin-1 receptor-associated kinase 1-binding protein 1 homolog

GENE ID SPECIES
100229738 Taeniopygia guttata
100352510 Oryctolagus cuniculus
134728 Homo sapiens
65099 Mus musculus
553809 Danio rerio
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