anti-Involucrin (IVL) Antibodies

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. Additionally we are shipping Involucrin Kits (31) and Involucrin Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IVL 3713 P07476
IVL 60583 P48998
IVL 16447  
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Top anti-Involucrin Antibodies at

Showing 10 out of 200 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-IVL Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Involucrin staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Involucrin staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Dog Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IP, WB Immunohistochemistry-Paraffin: Involucrin Antibody (SY5) [ABIN251172] - Staining of human Tonsil with Involucrin Monoclonal Antibody (SY5). Immunohistochemistry-Paraffin: Involucrin Antibody (SY5) [ABIN251172] - Formalin fixed paraffin embedded human skin stained with Involucrin antibody. 0.1 mg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
Dog Mouse Un-conjugated IHC (fro), IF, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), WB 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Dog Mouse Un-conjugated ICC, IF, IHC, IP, WB   0.1 mg Log in to see 7 to 9 Days
Dog Mouse Un-conjugated IHC (fro), IHC (p), IP, ELISA, WB Anti-IVL / Involucrin antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960541 concentration 10 ug/ml. 50 μg Log in to see 7 to 9 Days

IVL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) ,
Mouse (Murine) ,

Top referenced anti-Involucrin Antibodies

  1. Dog (Canine) Monoclonal IVL Primary Antibody for ICC, IF - ABIN251218 : Peramo, Feinberg, Marcelo: A putative in vitro organotypic model of molting with human skin explants. in Archives of dermatological research 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal IVL Primary Antibody for IF (p), IHC (p) - ABIN873324 : Xu, Zhang, Cheng, Liu, Zou, Zhan, Xiao, Xia: Transcription factor 7-like 1 dysregulates keratinocyte differentiation through upregulating lipocalin 2. in Cell death discovery 2016 (PubMed)

  3. Dog (Canine) Monoclonal IVL Primary Antibody for IHC (fro), IHC (p) - ABIN2475121 : Hudson, Weiland, Dooley, Simon, Watt: Characterisation of eight monoclonal antibodies to involucrin. in Hybridoma 1992 (PubMed)
    Show all 4 Pubmed References

  4. Dog (Canine) Monoclonal IVL Primary Antibody for CyTOF, FACS - ABIN251172 : Shimoda, Terazawa, Hitoe, Tanaka, Nakamura, Matsuda, Yoshikawa: Changes in ceramides and glucosylceramides in mouse skin and human epidermal equivalents by rice-derived glucosylceramide. in Journal of medicinal food 2012 (PubMed)

More Antibodies against Involucrin Interaction Partners

Human Involucrin (IVL) interaction partners

  1. Together, these results suggest that GR modulates involucrin expression of keratinocytes by regulating the intracellular signaling network in a ligand-independent manner.

  2. over-expression of Nnat (show NNAT Antibodies) was evident along with involucrin and cytokeratin1 expression

  3. involucrin is up-regulated in psoriatic keratinocytes

  4. KLF4 (show KLF4 Antibodies) is part of a multiprotein complex that interacts that the hINV promoter distal regulatory region to drive differentiation-dependent hINV gene expression in epidermis.

  5. Compared with the control, the level of expression of the IVL gene in NCTC 2544 cells was increased after 8 h of treatment with hyaluronic acid or Plantaricin A preparations.

  6. Therefore, together with trichohyalin (show TCHH Antibodies), the cross-linking due to involucrin is also responsible for the mechanical resistance of the corneous trabeculae present among the empty spaces of the medulla of the human hair.

  7. The authors found that HPV 16 E6 but not E7 repressed IVL promoter activity in proliferating human foreskin keratinocyte cells.

  8. expression of the epidermal differentiation complex genes filaggrin (show FLG Antibodies) and involucrin was strongly decreased directly by IL-13 (show IL13 Antibodies).

  9. Transcriptional activation of the involucrin gene by calcium in keratinocytes.

  10. involucrin gene contains distinct regulatory elements that regulate expression during epidermal differentiation

Mouse (Murine) Involucrin (IVL) interaction partners

  1. The Inv (show INVS Antibodies)-Cldn6 (show CLDN6 Antibodies)-CDelta206 transgenic mice displayed a developmental delay in epidermal permeability barrier formation, as shown by the expression of keratins and Cldns, and by X-Gal (show GAL Antibodies) penetration assays.

  2. the normally robust injury response mechanism of the epidermis is lost in the aging Involucrin-Cldn6 (show CLDN6 Antibodies)-CDelta196 transgenic epidermis

  3. analysis of evolutionary relations of the mouse based on repeats at a precise location in the coding region of the involucrin gene

  4. Skin biopsies from STAT6 (show STAT6 Antibodies) transgenic mice were deficient in the expression and production of loricrin (show LOR Antibodies) and involucrin.

Involucrin (IVL) Antigen Profile

Protein Summary

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.

Gene names and symbols associated with anti-Involucrin (IVL) Antibodies

  • involucrin (IVL) antibody
  • involucrin (Ivl) antibody
  • 1110019C06Rik antibody
  • IVL antibody

Protein level used designations for anti-Involucrin (IVL) Antibodies


713728 Macaca mulatta
736637 Pan troglodytes
3713 Homo sapiens
609423 Canis lupus familiaris
407242 Sus scrofa
60583 Rattus norvegicus
280830 Bos taurus
100731617 Cavia porcellus
16447 Mus musculus
100972032 Pan paniscus
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