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Iroquois Homeobox 3 Proteins (IRX3)

IRX3 is a member of the Iroquois homeobox gene family (see IRX1\; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Additionally we are shipping IRX3 Antibodies (91) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat IRX3 IRX3 307721  
IRX3 79191 P78415
IRX3 16373 P81067
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Top IRX3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details

IRX3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Iroquois Homeobox 3 (IRX3) Interaction Partners

Human Iroquois Homeobox 3 (IRX3) interaction partners

  1. Strategies to pharmacologically regulate Irx3 function in adult endothelial cells may provide new therapies for angiogenesis.

  2. data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO (show FTO Proteins) and represents a novel determinant of body mass and composition

  3. IRX3 function may have a direct functional relationship to both obesity and type 2 diabetes.

Xenopus laevis Iroquois Homeobox 3 (IRX3) interaction partners

  1. barH-like homeobox-2 (show BARHL2 Proteins) gene barhl2 (show BARHL2 Proteins) acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog (show SHH Proteins)

  2. Irx3 is transcriptionally induced by the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway during anteroposterior patterning of the neural axis.

  3. Irx3 is the first gene known to be necessary and sufficient to specify nephron segment fate in vivo.

Mouse (Murine) Iroquois Homeobox 3 (IRX3) interaction partners

  1. Irx3 and Irx5 (Irx3/5) are essential in the initiating limb bud to specify progenitors of the femur, tibia, and digit 1.

  2. data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO (show FTO Proteins) and represents a novel determinant of body mass and composition

  3. postnatal Irx3 activity can be repressed by Irx5 (show IRX5 Proteins)

  4. Irx3 is critical for efficient conduction in this specialized tissue by antithetically regulating two gap junction-forming connexins

  5. Irx3 signal is restricted to the somatic cell component of XX gonads and is present at a discreet period of ovarian development that ends at birth.

IRX3 Protein Profile

Protein Summary

IRX3 is a member of the Iroquois homeobox gene family (see IRX1\; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998

Gene names and symbols associated with Iroquois Homeobox 3 Proteins (IRX3)

  • iroquois homeobox 3 (IRX3)
  • iroquois homeobox 3 (Irx3)
  • iroquois homeobox 3 (irx3)
  • Iroquois related homeobox 3 (Drosophila) (Irx3)
  • AI894186 protein
  • iro3 protein
  • IRX-1 protein
  • irx3b protein
  • IRXB1 protein
  • xiro-3 protein
  • xiro3 protein

Protein level used designations for Iroquois Homeobox 3 Proteins (IRX3)

iroquois homeobox protein 3 , iroquois-class homeodomain protein IRX-3 , Iroquois related homeobox 3 , homeodomain protein IRXB1 , iroquois-class homeodomain protein IRX-1 , Iroquois homeobox protein 3 , homeobox transcription factor iroquois 3 , iroquois type homeobox , iroquois-class homeodomain protein irx-3

GENE ID SPECIES
487277 Canis lupus familiaris
540417 Bos taurus
307721 Rattus norvegicus
79191 Homo sapiens
399365 Xenopus laevis
16373 Mus musculus
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