anti-K(lysine) Acetyltransferase 8 (KAT8) Antibodies

KAT8 encodes a member of the MYST histone acetylase protein family. Additionally we are shipping K(lysine) Acetyltransferase 8 Kits (7) and K(lysine) Acetyltransferase 8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KAT8 310194 Q5XI06
KAT8 84148 Q9H7Z6
KAT8 67773 Q9D1P2
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Top anti-K(lysine) Acetyltransferase 8 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-MYST1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-HMOF/MYST1(C-term) Pab (ABIN387971) in K562 cell line lysates (35 µg/lane). HMOF/MYST1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) (ABIN387971), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB 100 μL Log in to see 2 to 3 Days
$393.80
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYST1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$335.00
Details
Human Mouse Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 7 to 9 Days
$451.00
Details

KAT8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-K(lysine) Acetyltransferase 8 Antibodies

  1. Human Monoclonal KAT8 Primary Antibody for ICC, IHC - ABIN1724671 : Neal, Pannuti, Smith, Lucchesi: A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. in Biochimica et biophysica acta 2000 (PubMed)
    Show all 3 Pubmed References

More Antibodies against K(lysine) Acetyltransferase 8 Interaction Partners

Human K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. These findings provide insight into the regulation of LSD1 (show KDM1A Antibodies) and Epithelial-to-Mesenchymal Transition (EMT (show ITK Antibodies)) and identify MOF as a critical suppressor of EMT (show ITK Antibodies) and tumor progression.

  2. This work identifies MOF as a key regulator of cellular stress response in glomerular podocytes.

  3. recent results indicate MOF is an upstream regulator of the ATM (ataxia-telangiectasia mutated (show ATM Antibodies)) protein, the loss of which is responsible for ataxia telangiectasia (AT). ATM (show ATM Antibodies) is a key regulatory kinase that interacts with and phosphorylates multiple substrates that influence critical, cell-cycle control and DNA damage repair pathways in addition to other pathways.

  4. Histone acetyltransferase (show HAT Antibodies) activity of MOF is required to sustain MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) leukemia and may be important for multiple AML (show RUNX1 Antibodies) subtypes.

  5. our findings reveal that TET1 (show TET1 Antibodies) forms a complex with hMOF to modulate its function and the level of H4K16Ac ultimately affect gene expression and DNA repair.

  6. these studies point to the critical and specific role of hMOF Lys (show LYZ Antibodies)-274 autoacetylation in hMOF stability and cognate substrate acetylation and argues that binding of Ac-CoA to hMOF likely drives Lys (show LYZ Antibodies)-274 autoacetylation for subsequent cognate substrate acetylation.

  7. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  8. MOF is highly enriched in induced pluripotent stem cells (iPSCs), and MOF expression is upregulated during the reprogramming process. The ectopic expression of MOF promotes reprogramming. MOF affects Wdr5 (show WDR5 Antibodies) and endogenous Oct4 (show POU5F1 Antibodies) expression.

  9. Along with the PHF20 (show PHF20 Antibodies)/MOF complex, G9a (show EHMT2 Antibodies) links the crosstalk between ERalpha (show ESR1 Antibodies) methylation and histone acetylation that governs the epigenetic regulation of hormonal gene expression.

  10. Data found downregulation of hMOF in gastric cancer cells and tissues. Declined hMOF expression, but not high level of HDAC4 (show HDAC4 Antibodies), may account for global histone H4K16ac suggesting that loss of hMOF expression may be involved in gastric cancer progression.

Mouse (Murine) K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. This work identifies MOF as a key regulator of cellular stress response in glomerular podocytes.

  2. demonstrate that KAT8 is essential for female fertility by regulating antioxidant gene expression and identify KAT8 as the first histone acetyltransferase (show HAT Antibodies) with an essential function in oogenesis

  3. MOF is a developmental-stage-specific chromatin regulator found to be essential for adult but not early fetal hematopoiesis.

  4. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  5. STAT5B (show STAT5B Antibodies) and MOF work as negative regulators in adipogenesis.

  6. NSL and MSL HAT (show HAT Antibodies) complexes differentially regulate specific sets of expressed genes in mESCs and during differentiation

  7. cardiac-specific MOF overexpression protected mice from transverse aortic constriction-induced cardiac hypertrophy, with reduced radios of heart weight/body weight, decreased left ventricular wall thickness and increased fractional shortening.

  8. Mof plays a critical role in T-cell differentiation and that depletion of Mof in T cells reduces T-cell numbers and, by an undefined mechanism, induces genomic instability in B cells through bystander mechanism.

  9. Depletion of MOF in mouse embryonic stem cells causes a specific decrease in expression of a subset of X-linked genes.

  10. the histone acetyltransferase Mof plays an essential role in the maintenance of ESC self-renewal and pluripotency

K(lysine) Acetyltransferase 8 (KAT8) Antigen Profile

Protein Summary

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KAT8

  • MYST histone acetyltransferase 1 (myst1) antibody
  • K(lysine) acetyltransferase 8 (kat8) antibody
  • K(lysine) acetyltransferase 8 (MYST1) antibody
  • MYST histone acetyltransferase 1 (MYST1) antibody
  • MYST histone acetyltransferase 1 (LOC100341732) antibody
  • K (lysine) acetyltransferase 8 (Kat8) antibody
  • K(lysine) acetyltransferase 8 (KAT8) antibody
  • K(lysine) acetyltransferase 8 (Kat8) antibody
  • 2010203C02Rik antibody
  • 5830450F21Rik antibody
  • D7Ertd629e antibody
  • hMOF antibody
  • MOF antibody
  • MYST1 antibody
  • wu:fb22g02 antibody
  • wu:fj22d09 antibody
  • ZC2HC8 antibody
  • zgc:66387 antibody

Protein level used designations for KAT8

MYST histone acetyltransferase 1 , histone acetyltransferase KAT8 , K(lysine) acetyltransferase 8 , probable histone acetyltransferase MYST1-like , MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 , MYST protein 1 , MYST-1 , lysine acetyltransferase 8 , probable histone acetyltransferase MYST1 , histone acetyltransferase MYST1 , ortholog of Drosophila males absent on the first (MOF) , histone acetyltransferase Myst1

GENE ID SPECIES
548988 Xenopus (Silurana) tropicalis
100003790 Danio rerio
100019305 Monodelphis domestica
100064910 Equus caballus
100341732 Oryctolagus cuniculus
100387289 Callithrix jacchus
100435717 Pongo abelii
100522367 Sus scrofa
100593658 Nomascus leucogenys
310194 Rattus norvegicus
84148 Homo sapiens
67773 Mus musculus
479777 Canis lupus familiaris
100125883 Bos taurus
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