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The protein encoded by KRT3 is a member of the keratin gene family. Additionally we are shipping Keratin 3 Proteins (4) and many more products for this protein.
Showing 10 out of 36 products:
Rabbit Monoclonal KRT3 Primary Antibody for FACS, IHC (p) - ABIN108617
Schermer, Galvin, Sun: Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. in The Journal of cell biology 1986
Show all 4 Pubmed References
Loss of normal CKB (show CHKB Antibodies) structure and function contributes to the mechanisms by which isoaspartate accumulation leads to central nervous system dysfunction in the PIMT (show PCMT1 Antibodies)-Knockout mouse.
CKB (show CHKB Antibodies) plays a key role in myotube formation by limiting myoblast fusion during myogenesis.
BCK (show CKB Antibodies) phosphorylation at Ser6 did not affect its enzymatic activity, but led to the appearance of the phosphorylated enzyme at the endoplasmic reticulum (ER)
Hypothalamic plasticity of neuropeptide Y (show NPY Antibodies) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation
negative regulation of CKB (show CHKB Antibodies) by mHTT is a key event in the pathogenesis of HD and contributes to the neuronal dysfunction associated with HD.
reduced expression of brain creatine kinase (show CKB Antibodies) in the cochlea of Huntington disease (show HTT Antibodies) mice is associated with hearing impairment
In rat cerebrum and cerebellum, as in rat heart, at all ages the several cCK (show CCK Antibodies) isoenzymes do participate in a gender-specific manner, in favor of females, in diverse functions of the different cell compartments of glial and neuronal cells.
cytoskeletal dynamics during cell motility is coupled to on-site availability of ATP generated by CKB (show CHKB Antibodies)
we show that the two PAX6 (show PAX6 Antibodies) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12 (show KRT12 Antibodies)). PAX6 (show PAX6 Antibodies) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (show KLF4 Antibodies) enhanced this induction. A combination of PAX6 (show PAX6 Antibodies) isoform-b, KLF4 (show KLF4 Antibodies), and OCT4 (show POU5F1 Antibodies) induced KRT12 (show KRT12 Antibodies) expression
Exon sequencing of KRT3 and KRT12 (show KRT12 Antibodies) in six affected and eight unaffected individuals did not detect any mutations or nucleotide sequence variants in Meesmann epithelial corneal dystrophy.
A novel missense mutation (R503P) in KRT3 leads to MCD in 2 unrelated Taiwanese families.
Location of the E498V mutation emphasizes the functional relevance of the highly conserved boundary motifs at the COOH-terminus of the alpha-helical rod domain in keratin 3 (K3).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
, cytokeratin Ib (human cytokeratin 3)
, creatine kinase B chain
, creatine kinase B-type
, 65 kDa cytokeratin
, cytokeratin 3
, keratin, type II cytoskeletal 3
, type-II keratin Kb3
, K3 keratin
, Type-II keratin Kb3
, keratin K3