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Keratin 86 Proteins (KRT86)

The protein encoded by KRT86 is a member of the keratin gene family. Additionally we are shipping Keratin 86 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat KRT86 KRT86 407760  
KRT86 3892 O43790
KRT86 16679 P97861
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Top Keratin 86 Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days

KRT86 Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

More Proteins for Keratin 86 (KRT86) Interaction Partners

Human Keratin 86 (KRT86) interaction partners

  1. Analysis of KRT86 revealed a novel mutation, c.1231G>T;p.Glu411*, in exon 7 in the three affected children and their mother with monilethrix.

  2. Novel mutations causing monilethrix are reported in KRT81 (show KRT81 Proteins), KRT83 (show KRT83 Proteins), and KRT86.

  3. The mutation of extron 7 of KRT86 identified plays a major role in the pathogenesis of this pedigree with monilethrix.

  4. Congenital monilethrix and hereditary unilateral external auditory canal atresia are co-inherited in a Chinese pedigree with recurrent KRT86 mutation.

  5. Results idntify a novel mutation of krt86 protein causing monilethrix located in a region other than the helix.

  6. The KRTHB6 expression uniformly occurred in the midcortex region.

  7. The results emphasized the key role of hair keratin hHB6 in the pathogenesis of monilethrix and indicated that the common mutation of hHB6 was also a cause of monilethrix in Chinese.

  8. Mutation E402K of the hHb6 in a Chinese Han family with monilethrix.

Keratin 86 (KRT86) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle\; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.

Gene names and symbols associated with Keratin 86 Proteins (KRT86)

  • keratin 86 (Krt86)
  • keratin 86 (KRT86)
  • hair keratin type II intermediate filament (KRT2.11)
  • 5430421N21Rik protein
  • AI325212 protein
  • Hb1 protein
  • HB6 protein
  • hHb6 protein
  • Kb26 protein
  • Khb4 protein
  • Krt2-10 protein
  • Krt2-11 protein
  • KRT86 protein
  • KRTHB1 protein
  • KRTHB6 protein
  • MHb4 protein
  • MNX protein

Protein level used designations for Keratin 86 Proteins (KRT86)

keratin, type II cuticular Hb6 , type II keratin Kb26 , keratin 86 , hair keratin type II intermediate filament , K86 , hair keratin K2.11 , hard keratin, type II, 6 , keratin protein HB6 , keratin, hair, basic, 6 (monilethrix) , keratin-86 , type II hair keratin Hb6 , type-II keratin Kb26 , keratin complex 2, basic, gene 10

407760 Rattus norvegicus
466985 Pan troglodytes
486530 Canis lupus familiaris
535232 Bos taurus
443415 Ovis aries
100026816 Monodelphis domestica
100062959 Equus caballus
100602869 Nomascus leucogenys
3892 Homo sapiens
16679 Mus musculus
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