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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) Antibodies

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KIR2DL4 3805 Q99706
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Top anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 Antibodies at antibodies-online.com

Showing 10 out of 116 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of KIR2DL4 Antibody (C-term) (ABIN652985) in MDA-MB231 cell line lysates (35 µg/lane). KIR2DL4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with KIR2DL4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB Human recombinant protein KIR2DL1, KIR2DL3 and KIR2DL4 (each 20ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DL4 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a ECL detection system * Lane 1 : Extracellular domain of KIR2DL1(23-223aa) Lane 2 : Extracellular domain of KIR2DL3(23-223aa) Lane 3 : Extracellular domain of KIR2DL4(44-202aa) 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated Func, FACS, IF, IP, WB   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$357.50
Details
Human Mouse PE Func, ICC, FACS, IP, WB   100 Tests Log in to see 4 to 5 Days
$334.95
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of MDA-MB231 cells using CD158d / KIR2DL4 Antibody (C-term) Cat.-No AP52370PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CD158d / KIR2DL4 Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated Func, ICC, FACS, IP, WB   0.1 mg Log in to see 4 to 5 Days
$288.75
Details
Human Mouse Un-conjugated BR, FACS 50 μg Log in to see 10 to 12 Days
$211.97
Details
Human Mouse PE FACS, IP 100 Tests Log in to see 10 to 12 Days
$320.68
Details

KIR2DL4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 Antibodies

  1. Human Monoclonal KIR2DL4 Primary Antibody for FACS, IP - ABIN2663066 : Rajagopalan, Bryceson, Kuppusamy, Geraghty, van der Meer, Joosten, Long: Activation of NK cells by an endocytosed receptor for soluble HLA-G. in PLoS biology 2006 (PubMed)
    Show all 7 references for ABIN2663066

  2. Human Monoclonal KIR2DL4 Primary Antibody for Func, ICC - ABIN509568 : LeMaoult, Zafaranloo, Le Danff, Carosella: HLA-G up-regulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)
    Show all 5 references for ABIN509568

  3. Human Monoclonal KIR2DL4 Primary Antibody for BR, FACS - ABIN2665558 : Goodridge, Lathbury, Steiner, Shulse, Pullikotil, Seidah, Hurley, Christiansen, Witt: Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells. in European journal of immunology 2006 (PubMed)
    Show all 5 references for ABIN2665558

  4. Human Monoclonal KIR2DL4 Primary Antibody for Func, ICC - ABIN489933 : Goodridge, Witt, Christiansen, Warren: KIR2DL4 (CD158d) genotype influences expression and function in NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 references for ABIN489933

  5. Human Monoclonal KIR2DL4 Primary Antibody for FACS - ABIN614806 : Yan, Fan: Residues Met76 and Gln79 in HLA-G alpha1 domain involve in KIR2DL4 recognition. in Cell research 2005 (PubMed)
    Show all 5 references for ABIN614806

  6. Human Monoclonal KIR2DL4 Primary Antibody for Func, FACS - ABIN614805 : Rajagopalan, Fu, Long: Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 references for ABIN614805

  7. Human Monoclonal KIR2DL4 Primary Antibody for EIA, WB - ABIN121169 : Chwae, Chang, Park, Yoon, Park, Kim, Kim: Molecular mechanism of the activation-induced cell death inhibition mediated by a p70 inhibitory killer cell Ig-like receptor in Jurkat T cells. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 2 references for ABIN121169

  8. Human Polyclonal KIR2DL4 Primary Antibody for FACS, IHC (p) - ABIN652985 : Wi?niewski, Kowal, Wyrodek, Nowak, Majorczyk, Wagner, Pawlak-Adamska, Jankowska, ?lesak, Frydecka, Ku?nierczyk: Genetic polymorphisms and expression of HLA-G and its receptors, KIR2DL4 and LILRB1, in non-small cell lung cancer. in Tissue antigens 2015 (PubMed)

  9. Human Polyclonal KIR2DL4 Primary Antibody for WB - ABIN2777111 : Schellekens, Tilanus, Rozemuller: The elucidation of KIR2DL4 gene polymorphism. in Molecular immunology 2008 (PubMed)

More Antibodies against Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) interaction partners

  1. Decreased level of KIR2DL4 rather than its single nucleotide polymorphism is correlated with the susceptibility of pre-eclampsia

  2. the KIR2DL4 on human mast cells facilitates HLA-G (show HLAG Antibodies)-expressing cancer invasion and the subsequent metastasis.

  3. Among 438 Polish people, a weak difference was seen between males and females in 9769 C/A genotypes and alleles. Fertile women had a high frequency of homozygosity for the defective 9A variant, so KIR2DL4 is not absolutely necessary for reproduction.

  4. Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (show KIR2DS1 Antibodies) (KIR (show GEM Antibodies)) genes.

  5. Results show that HLA-E (show HLAE Antibodies) and KIR2DL4 demonstrate evidence of positive selection between human, chimpanzee and gorilla suggesting a main role for immunological adaptations linked to embryo deep invasion of the maternal endometrium during pregnancy.

  6. The unique functional properties of KIR2DL4 may be mediated by self-association of the receptor.

  7. Genetic polymorphism of KIR2DL4, a putative NK cell receptor for HLA-G (show HLAG Antibodies), does not influence susceptibility to asthma.

  8. Abs to KIR2DL4 and HLA-G (show HLAG Antibodies) did not block NK cell IFN-gamma (show IFNG Antibodies) production.

  9. KIR2DL4 was found to directly interact with HS/heparin, and the D0 domain of KIR2DL4 was essential for this interaction.

  10. Beta Microglobulin-free HLA-G (show HLAG Antibodies) activates NK cells via engagement of KIR2DL4 receptors.

Rhesus Monkey Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) interaction partners

  1. Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

  2. In the Indian population, two different KIR2DL4 entities are encountered, which differ in their intra-cellular signalling motifs. One genotype contains a complex mutation in the distal region of exon 9, which negates a serine/threonine kinase site.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) Antigen Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KIR2DL4

  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4) antibody
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A (KIR2DL5A) antibody
  • CD158D antibody
  • G9P antibody
  • KIR2DL1 antibody
  • KIR2DL4 antibody
  • KIR103 antibody
  • KIR103AS antibody

Protein level used designations for KIR2DL4

CD158 antigen-like family member D , KIR-103AS , MHC class I NK cell receptor KIR103AS , NK cell receptor , killer Ig receptor , killer cell immunoglobulin-like receptor 2DL4 , killer cell inhibitory receptor 103AS , natural killer cell inhibitory receptor , killer cell immunoglobulin-like receptor 2DL5A , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5 , killer cell immunoglobulin-like receptor KIR2DL4 , killer cell immunogobulin-like receptor two domains long cytoplasmic tail 4

GENE ID SPECIES
3805 Homo sapiens
282860 Bos taurus
450205 Pan troglodytes
722782 Macaca mulatta
100137355 Papio anubis
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