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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 Proteins (10) and many more products for this protein.
Showing 10 out of 122 products:
Human Monoclonal KIR2DL4 Primary Antibody for FACS, IP - ABIN2663066
Rajagopalan, Bryceson, Kuppusamy, Geraghty, van der Meer, Joosten, Long: Activation of NK cells by an endocytosed receptor for soluble HLA-G. in PLoS biology 2006
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Human Monoclonal KIR2DL4 Primary Antibody for BR, FACS - ABIN2665558
Goodridge, Lathbury, Steiner, Shulse, Pullikotil, Seidah, Hurley, Christiansen, Witt: Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells. in European journal of immunology 2006
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Human Monoclonal KIR2DL4 Primary Antibody for FACS - ABIN614806
Yan, Fan: Residues Met76 and Gln79 in HLA-G alpha1 domain involve in KIR2DL4 recognition. in Cell research 2005
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Human Monoclonal KIR2DL4 Primary Antibody for Func, FACS - ABIN614805
Rajagopalan, Fu, Long: Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Human Monoclonal KIR2DL4 Primary Antibody for FACS - ABIN4898687
Baudhuin, Lesport, Sousa, Migraine, Vigneron, Lemaoult, Carosella, Mooney, Favier: HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization. in European journal of immunology 2012
Show all 4 references for ABIN4898687
Human Monoclonal KIR2DL4 Primary Antibody for EIA, WB - ABIN121169
Chwae, Chang, Park, Yoon, Park, Kim, Kim: Molecular mechanism of the activation-induced cell death inhibition mediated by a p70 inhibitory killer cell Ig-like receptor in Jurkat T cells. in Journal of immunology (Baltimore, Md. : 1950) 2002
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Human Monoclonal KIR2DL4 Primary Antibody for FACS - ABIN4898685
Dunphy, Guinan, Chorcora, Jayaraman, Traherne, Trowsdale, Pende, Middleton, Gardiner: 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells. in Genes and immunity 2015
Human Polyclonal KIR2DL4 Primary Antibody for FACS, IHC (p) - ABIN652985
Wi?niewski, Kowal, Wyrodek, Nowak, Majorczyk, Wagner, Pawlak-Adamska, Jankowska, ?lesak, Frydecka, Ku?nierczyk: Genetic polymorphisms and expression of HLA-G and its receptors, KIR2DL4 and LILRB1, in non-small cell lung cancer. in Tissue antigens 2015
Human Polyclonal KIR2DL4 Primary Antibody for WB - ABIN2777111
Schellekens, Tilanus, Rozemuller: The elucidation of KIR2DL4 gene polymorphism. in Molecular immunology 2008
a woman's heterozygosity in HLA-G (show HLAG Antibodies) and LILRB1 (show LILRB1 Antibodies) might be an advantage for a success of reproduction, but the partner's heterozygosity in 9A/10A KIR2DL4 alleles might not
Decreased level of KIR2DL4 rather than its single nucleotide polymorphism is correlated with the susceptibility of pre-eclampsia
the KIR2DL4 on human mast cells facilitates HLA-G (show HLAG Antibodies)-expressing cancer invasion and the subsequent metastasis.
Among 438 Polish people, a weak difference was seen between males and females in 9769 C/A genotypes and alleles. Fertile women had a high frequency of homozygosity for the defective 9A variant, so KIR2DL4 is not absolutely necessary for reproduction.
Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (show KIR2DS1 Antibodies) (KIR (show GEM Antibodies)) genes.
Results show that HLA-E (show HLAE Antibodies) and KIR2DL4 demonstrate evidence of positive selection between human, chimpanzee and gorilla suggesting a main role for immunological adaptations linked to embryo deep invasion of the maternal endometrium during pregnancy.
The unique functional properties of KIR2DL4 may be mediated by self-association of the receptor.
Genetic polymorphism of KIR2DL4, a putative NK cell receptor for HLA-G (show HLAG Antibodies), does not influence susceptibility to asthma.
Abs to KIR2DL4 and HLA-G (show HLAG Antibodies) did not block NK cell IFN-gamma (show IFNG Antibodies) production.
KIR2DL4 was found to directly interact with HS/heparin, and the D0 domain of KIR2DL4 was essential for this interaction.
Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.
In the Indian population, two different KIR2DL4 entities are encountered, which differ in their intra-cellular signalling motifs. One genotype contains a complex mutation in the distal region of exon 9, which negates a serine/threonine kinase site.
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants.
CD158 antigen-like family member D
, MHC class I NK cell receptor KIR103AS
, NK cell receptor
, killer Ig receptor
, killer cell immunoglobulin-like receptor 2DL4
, killer cell inhibitory receptor 103AS
, natural killer cell inhibitory receptor
, killer cell immunoglobulin-like receptor 2DL5A
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5
, killer cell immunoglobulin-like receptor KIR2DL4
, killer cell immunogobulin-like receptor two domains long cytoplasmic tail 4