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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Antibodies (40) and Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Kits (1) and many more products for this protein.
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Human KLRC2 Protein expressed in Escherichia coli (E. coli) - ABIN1098669
Shum, Flodin, Muir, Rajalingam, Khakoo, Cleland, Guethlein, Uhrberg, Parham: Conservation and variation in human and common chimpanzee CD94 and NKG2 genes. in Journal of immunology (Baltimore, Md. : 1950) 2001
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HLA-E (show HLAE Proteins) regulates NKG2C+ natural killer cell function through presentation of a restricted peptide repertoire
Data suggest the proinflammatory potential of NKG2C(bright) NK cells.
lack of expression of NKG2C may be associated with altered control of human cytomegalovirus infection in childhood
No difference in the prevalence of NKG2C deletion was observed.
NKG2C receptor deletion and a functional polymorphism in its ligand HLA-E may play a role in psoriasis susceptibility
NKG2C(hi)CD57 (show B3GAT1 Proteins)+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus.
NKG2C zygosity influences CD94 (show KLRD1 Proteins)/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus.
coexpression of killer cell Ig-like receptor (KIR) and NKG2C on expanded NK cell subsets could be related to a functional contribution of KIR in cytomegalovirus infection
The increased expression of NKG2C in HIV patients indicate that NKG2C is important in the defense against HIV infection and progression.
A significantly elevated proportion of ex vivo peripheral blood CD4 (show CD4 Proteins) T cells, but not CD8 (show CD8A Proteins) T cells or natural killer (NK) cells, from multiple sclerosis patients express NKG2C, which contributes to tissue injury.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
CD159 antigen-like family member C
, NK cell receptor C
, NKG2-C type II integral membrane protein
, NKG2-C-activating NK receptor