KLRC2 Protein (AA 94-231) (His tag)
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- Target See all KLRC2 Proteins
- KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 94-231
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KLRC2 protein is labelled with His tag.
- Characteristics
- Human NKG2C / CD159c Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KLRC2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
- Alternative Name
- NKG2C (KLRC2 Products)
- Synonyms
- CD159c Protein, NKG2-C Protein, NKG2C Protein, killer cell lectin like receptor C2 Protein, killer cell lectin-like receptor subfamily C, member 2 Protein, KLRC2 Protein
- Background
- Human NKG2C (NK cell Group 2 isoform C, Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.
- Molecular Weight
- 17.8 kDa
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