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Killer Cell Lectin-Like Receptor Subfamily G, Member 1 Proteins (KLRG1)

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping KLRG1 Antibodies (139) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLRG1 50928 O88713
KLRG1 10219 Q96E93
Rat KLRG1 KLRG1 58975 Q64335
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Top KLRG1 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

KLRG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, , ,

Top referenced KLRG1 Proteins

  1. Human KLRG1 Protein expressed in Escherichia coli (E. coli) - ABIN1098733 : Ibegbu, Xu, Harris, Maggio, Miller, Kourtis: Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 2 references for ABIN1098733

More Proteins for Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) Interaction Partners

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) interaction partners

  1. This finding provides a rationale for the reciprocal expression of KLRG1 and CD103 (show ITGAE Proteins) in different CD8 (show CD8A Proteins)(+) T-cell subsets.

  2. Cytotoxic KLRG1-expressed CD8 (show CD8A Proteins) effector cells and defective T regulatory cells cause murine autoimmune cholangitis.

  3. KLRG1(+) iNKT cells coexpressing CD49d and granzyme A (show GZMA Proteins) persisted for several months and displayed a potent secondary response to cognate antigen.

  4. high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 inhibitory function, indicating that TfRs may sequester KLRG1 from interacting with cadherins.

  5. data further demonstrate that the inhibitory activity of KLRG1 is decreased in T cells expressing high levels of TfR (show TFRC Proteins), indicating that association of KLRG1 with TfR (show TFRC Proteins) hinders KLRG1-mediated silencing.

  6. Data indicate that CD103 (show ITGAE Proteins)(+)CD8 (show CD8A Proteins)(+) T(RM) cells developed in the skin from epithelium-infiltrating precursor cells that lacked expression of the effector-cell marker KLRG1.

  7. Data indicate that increments of CD8 (show CD8A Proteins) + effector memory T cells in human and mouse chronic lymphocytic leukemia (CLL)(Emu-TCL1 (show TCL1A Proteins) model) were due to an expansion of the inhibitory killer cell lectin-like receptor G1 (KLRG1) expressing cellular subset.

  8. Despite their differences, KLRG1+ and KLRG1- Treg cells proved similarly potent in suppressing experimental autoimmune encephalomyelitis.

  9. KLRG1(-/-) mice had a significant survival extension after Mycobacterium tuberculosis infection compared to wild-type controls, and maintained a significantly lower level of pulmonary bacterial load throughout chronic infection.

  10. CD8+ T cells lacking Id2 do not generate a robust terminally differentiated killer cell lectin-like receptor G1 (KLRG1hi) effector population, but display a cell-surface phenotype and cytokine profile consistent with memory precursors.

Human Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) interaction partners

  1. This finding provides a rationale for the reciprocal expression of KLRG1 and CD103 (show ITGAE Proteins) in different CD8 (show CD8A Proteins)(+) T-cell subsets.

  2. high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 inhibitory function, indicating that TfRs may sequester KLRG1 from interacting with cadherins.

  3. More T cells were KLRG1+ in the synovial fluid of patients with spondylarthritis/rheumatoid arthritis than crystal arthritis or controls. Those T cells were more functionally active, and migrated towards the synovial fluid of SpA (show FASL Proteins)/RA patients.

  4. KLRG1 was overexpressed on CD4 (show CD4 Proteins)(+) T cells.

  5. Data indicate that increments of CD8 (show CD8A Proteins) + effector memory T cells in human and mouse chronic lymphocytic leukemia (CLL)(Emu-TCL1 (show TCL1A Proteins) model) were due to an expansion of the inhibitory killer cell lectin-like receptor G1 (KLRG1) expressing cellular subset.

  6. These results indicate that KLRG1 negatively regulates natural killer cell numbers and functions via the Akt (show AKT1 Proteins) pathway, thus providing a novel marker and therapeutic target for hepatitis C virus infection.

  7. cytomegalovirus positive had lower proportions of NK-cells expressing inhibitory receptors (KLRG1 and CD158a (show KIR2DL1 Proteins))

  8. trastuzumab-mediated antibody-dependent cellular cytotoxicity was markedly enhanced by KLRG1-negative peripheral blood mononuclear cells

  9. Results demonstrated a substantial reduction in both CD94 (show KLRD1 Proteins)- and KLRG1- expressing CD3 (show CD3 Proteins)(-)CD56 (show NCAM1 Proteins)(+) NK cells with increased age.

  10. Expression of MafA analyzed in conditional knockout mice during embryonic development is the first specific marker of a subpopulation of "early c-ret (show RET Proteins)" positive sensory neurons.

KLRG1 Protein Profile

Protein Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined.

Gene names and symbols associated with KLRG1

  • killer cell lectin-like receptor subfamily G, member 1 (KLRG1)
  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1)
  • 2F1 protein
  • 2F1-Ag protein
  • CLEC15A protein
  • KLRG1 protein
  • MAFA protein
  • MAFA-2F1 protein
  • MAFA-L protein
  • MAFA-LIKE protein

Protein level used designations for KLRG1

killer cell lectin-like receptor subfamily G, member 1 , killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , C-type lectin domain family 15 member A , C-type lectin domain family 15, member A , ITIM-containing receptor MAFA-L , MAFA-like receptor , mast cell function-associated antigen (ITIM-containing) , mast cell function-associated antigen

GENE ID SPECIES
611464 Canis lupus familiaris
736225 Pan troglodytes
50928 Mus musculus
10219 Homo sapiens
58975 Rattus norvegicus
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