anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Antibodies

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KLRC1 29683  
KLRC1 3821 P26715
KLRC1 16641  
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Top anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Antibodies at antibodies-online.com

Showing 10 out of 130 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KLRC1 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). KLRC1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Confocal immunofluorescent analysis of KLRC1 / CD159a Antibody (N-term) Cat.-No AP52396PU-N with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). Western blot analysis of KLRC1 / CD159a Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the KLRC1 antibody detected the KLRC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Allophycocyanin FACS Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC-conjugated Mono-clonal Antibody. 25 Tests Log in to see 8 to 9 Days
$140.70
Details
Human Mouse PE FACS Detection of NKG2A/CD159a in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$140.70
Details
Human Mouse PerCP FACS Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a PerCP-conjugated Mono-clonal Antibody. 25 Tests Log in to see 8 to 9 Days
$152.25
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-KLRC1 AntibodyTitration: 1.0 µg/mL  Positive Control: MCF7 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Anti-NKG2A Polyclonal Antibody, Unconjugated (ABIN739875) at 1:200 followed by conjugation to the secondary antibody 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, WB KLRC1 Antibody (N-term) (ABIN656501) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the KLRC1 antibody detected the KLRC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

KLRC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Antibodies

  1. Human Monoclonal KLRC1 Primary Antibody for FACS - ABIN4898769 : Kruse, Hamann, Monecke, Cyganek, Elsner, Hübscher, Walter, Streckfuss-Bömeke, Guan, Dressel: Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. in PLoS ONE 2015 (PubMed)
    Show all 13 references for 4898769

  2. Human Monoclonal KLRC1 Primary Antibody for FACS - ABIN4898762 : Gill, Peppa, Micco, Singh, Carey, Foster, Maini, Kennedy: Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo. in PLoS pathogens 2016 (PubMed)
    Show all 5 references for 4898762

  3. Human Polyclonal KLRC1 Primary Antibody for EIA, IF - ABIN953105 : Ma, Guo, Wu, Li, Zhu, Li, Li, Pan, Li, Li, Liu: Association of NKG2D genetic polymorphism with susceptibility to chronic hepatitis B in a Han Chinese population. in Journal of medical virology 2010 (PubMed)
    Show all 3 references for 953105

  4. Human Polyclonal KLRC1 Primary Antibody for ELISA, WB - ABIN1452141 : Sullivan, Clements, Beddoe, Johnson, Hoare, Lin, Huyton, Hopkins, Reid, Wilce, Kabat, Borrego, Coligan, Rossjohn, Brooks: The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition. in Immunity 2007 (PubMed)
    Show all 2 references for 1452141

  5. Human Polyclonal KLRC1 Primary Antibody for EIA, WB - ABIN453718 : Plougastel, Jones, Trowsdale: Genomic structure, chromosome location, and alternative splicing of the human NKG2A gene. in Immunogenetics 1996 (PubMed)
    Show all 2 references for 453718

  6. Mouse (Murine) Polyclonal KLRC1 Primary Antibody for IF (p), IHC (p) - ABIN739875 : Hall, Murphy, Quinlan, Hurley, Shanahan, Nally, Melgar: Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor. in Mucosal immunology 2013 (PubMed)
    Show all 2 references for 739875

  7. Human Monoclonal KLRC1 Primary Antibody for FACS - ABIN4898765 : Curriu, Carrillo, Massanella, Rigau, Alegre, Puig, Garcia-Quintana, Castro-Marrero, Negredo, Clotet, Cabrera, Blanco: Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome. in Journal of translational medicine 2013 (PubMed)

More Antibodies against Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) interaction partners

  1. These results indicate NKG2A inhibitory receptor may play a key role in transfusion-induced immunodepression of NK cells in patients with b-thalassemia major

  2. Collectively, these results provide evidence for the first time that CD94 (show KLRD1 Antibodies)/NKG2C (show KLRC2 Antibodies) is involved in chronic graft-versus-host disease prevention

  3. CD94 (show KLRD1 Antibodies) and NKG2A polymorphisms may contribute to genetic susceptibility to rheumatoid arthritis or affect the response to anti-TNF (show TNF Antibodies) therapy in patients of Caucasian origin.

  4. NK cell maturation to CD56(dim) subset associated with high levels of NCRs overrides the inhibitory effect of NKG2A and recovers impaired NK cell cytolytic potential after allogeneic hematopoietic stem cell transplantation.

  5. Coengagement of inhibitory receptors, either KIR2DL1 (show KIR2DL1 Antibodies) or CD94 (show KLRD1 Antibodies)-NKG2A, did not inhibit phosphorylation of Stat5 (show STAT5A Antibodies) but inhibited selectively phosphorylation of Akt (show AKT1 Antibodies) and S6 ribosomal protein (show RPS6 Antibodies).

  6. The presence of TIM3 (show HAVCR2 Antibodies)+and/or NKG2A+ T cells is associated with the absence of recurrences and a longer recurrence-free survival.

  7. Balance between activating NKG2D (show KLRK1 Antibodies), DNAM-1 (show CD226 Antibodies), NKp44 (show NCR2 Antibodies) and NKp46 (show NCR1 Antibodies) and inhibitory CD94 (show KLRD1 Antibodies)/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  8. Results suggested that the low expression level of CD94 (show KLRD1 Antibodies)/NKG2A upon gammadelta T cell activation might lead to the over-activation of gammadelta T cells in patients with SLE.

  9. The positive expression rate of NKG2D (show KLRK1 Antibodies) and NKG2A on NK cells and CD3 (show CD3 Antibodies)(+) T cells in ALL patients was no significantly different from that in AML (show RUNX1 Antibodies) patients.

  10. The level of NKG2A expression on resting CD8 (show CD8A Antibodies)-positive T cells inversely correlated with acquisition of regulatory function when activated.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) interaction partners

  1. Here, we provide a new anti-inflammation mechanism about ANXA1 (show ANXA1 Antibodies) secreted from injured IECs, where ANXA1 (show ANXA1 Antibodies) can stimulate the expression of NKG2A in NK cells that affect the recruitment and activity of neutrophils necessary for pathology of colitis.

  2. NKG2A optimizes CD8 (show CD8A Antibodies)(+) T cell responses during an acute poxvirus infection.

  3. Results demonstrate the immunoregulatory role of CD8 (show CD8A Antibodies)(+) NKG2A expression in virus infection, which negatively regulates T cell effector functions and contributes to protection of tissue integrity during virus clearance.

  4. role in NK cell-mediated protection from DSS (show PMP22 Antibodies)-induced colitis

  5. Endogenous NKG2A contributes to the rejection of cells lacking human HLA-Cw3.

  6. The complex interplay between various stimuli may account for the variable expression of CD94 (show KLRD1 Antibodies)/NKG2A during responses to different pathogens in vivo.

  7. expression of CD94 (show KLRD1 Antibodies) and its associated NKG2A, NKG2C (show KLRC2 Antibodies), and NKG2E (show KLRC3 Antibodies) subunits is dispensable for NK cell development, education, and many NK cell functions

  8. The NKG2A+KLRG1 (show KLRG1 Antibodies)+ positive phenotype correlates with protective efficacy during antigenic recall from a pool of CD8 (show CD8A Antibodies) T cells during persistent gamma-herpesvirus 68 infection.

  9. Data suggest that the liver environment regulates NK cell receptor expression and that IL-10 contributes to the regulation of liver NK cells, in part, by maintaining a greater percentage of the hyporesponsive NKG2A(+)Ly49(-) NK cells in the liver.

  10. Implications of CD94 (show KLRD1 Antibodies) deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation.

Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Antigen Profile

Protein Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Gene names and symbols associated with KLRC1

  • killer cell lectin-like receptor subfamily C, member 1 (Klrc1) antibody
  • killer cell lectin-like receptor subfamily C, member 1 (KLRC1) antibody
  • killer cell lectin-like receptor subfamily C, member 3 (KLRC3) antibody
  • CD159a antibody
  • KLRC1 antibody
  • NKG2 antibody
  • NKG2-A antibody
  • NKG2A antibody
  • NKG2B antibody
  • rNKG2A antibody

Protein level used designations for KLRC1

natural killer cell protein group 2-A (NKG2A) , CD159 antigen-like family member A , NK cell receptor A , NKG2-A/B-activating NK receptor , NKG2-A/NKG2-B type II integral membrane protein , killer cell lectin-like receptor subfamily C, member 1 , C-lectin type II protein , NKG2-1/B activating NK receptor , NKG2-A/B type II integral membrane protein , natural killer cell lectin , natural killer group protein 2

GENE ID SPECIES
29683 Rattus norvegicus
450131 Pan troglodytes
514897 Bos taurus
611325 Canis lupus familiaris
100126720 Papio anubis
100144622 Sus scrofa
3821 Homo sapiens
16641 Mus musculus
574146 Macaca mulatta
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