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Promotes mitotic spindle assembly. Additionally we are shipping Kinesin Family Member C1 Proteins (4) and many more products for this protein.
Showing 10 out of 32 products:
Human Monoclonal KIFC1 Primary Antibody for IF, IHC (p) - ABIN2475224
Zivkovic, Oblin, Bartholini: Progabide reverses the nigral substance P reduction induced by chronic impairment of dopaminergic transmission. in European journal of pharmacology 1985
Show all 2 Pubmed References
Human Polyclonal KIFC1 Primary Antibody for ICC, IF - ABIN4328857
Iemura, Tanaka: Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules. in Nature communications 2015
Human Monoclonal KIFC1 Primary Antibody for IF, IHC (p) - ABIN561612
Sati, Seval-Celik, Unek, Korgun, Demir: The presence of kinesin superfamily motor proteins KIFC1 and KIF17 in normal and pathological human placenta. in Placenta 2009
Knockdown of KIFC5A dramatically reduces ciliogenesis.
KIFC5A and the Nubp proteins in a common regulatory pathway involved in the control of centrosome duplication in mammalian cells.
Low post translational modifications of KIFC1 protein is associated with neoplasms.
KIFC1 is overexpressed in GC.
Association of KIFC1 gene expression and centrosome amplification with high-grade serous ovarian carcinoma.
stabilization of the centrosome-spindle pole interface by the CEP215 (show CDK5RAP2 Antibodies)-HSET complex could promote survival of cancer cells containing supernumerary centrosomes.
KIFC1 silencing significantly reduces breast cancer cell viability.
Data provides the first evidence of centrosome clustering-independent activities of HSET that fuel tumor progression.
We show that some are new substrates of the anaphase-promoting complex/cyclosome and validate KIFC1 and RacGAP1/Cyk4 as two such targets involved respectively in timely mitotic spindle disassembly and cell spreading
Our data underscore KIFC1 as a putative biomarker that predicts worse prognosis, poor overall survival and may serve as a potential marker of onset of metastatic dissemination in ovarian cancer patients.
Study demonstrates microtubule tip-tracking of human kinesin-14 HSET and show that EB1 (show MAPRE2 Antibodies) is sufficient to induce this dynamic microtubule end localization.
Acentrosomal spindle assembly mechanisms are hyperactive in cancer cells and promote HSET.
Promotes mitotic spindle assembly.
kinesin family c-terminal 5A
, kinesin family c-terminal 5B
, kinesin family member C5A
, kinesin-related protein KIFC5A
, kinesin-like protein 2
, kinesin-like protein KIFC1
, carboxy-terminal kinesin 2
, XCTK2-like motor protein
, kinesin family member C1
, kinesin motor protein KIFC4
, kinesin-like protein KIFC1-like
, kinesin-like 2
, kinesin-related protein HSET
, kinesin-like 2a
, kinesin-related protein 1
, kinesin-related protein KRP1