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KY encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
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Cow (Bovine) Monoclonal KY Primary Antibody for FACS - ABIN2477959
Farrier: The occurrence of 3-hydroxy-phenprobamate, a new metabolite of phenprobamate, in dogs and humans. in Arzneimittel-Forschung 1975
Show all 4 references for ABIN2477959
Pig (Porcine) Monoclonal KY Primary Antibody for FACS, IP - ABIN135460
Denham, Shimizu, Bianchi, Zwart, Carr, Parkhouse: Monoclonal antibodies recognising differentiation antigens on porcine B cells. in Veterinary immunology and immunopathology 1995
Show all 2 references for ABIN135460
Pig (Porcine) Monoclonal KY Primary Antibody for FACS, IP - ABIN135462
Pescovitz, Lunney, Sachs: Preparation and characterization of monoclonal antibodies reactive with porcine PBL. in Journal of immunology (Baltimore, Md. : 1950) 1984
Show all 2 references for ABIN135462
Human Polyclonal KY Primary Antibody for WB - ABIN654368
Beatham, Romero, Townsend, Hacker, van der Ven, Blanco: Filamin C interacts with the muscular dystrophy KY protein and is abnormally distributed in mouse KY deficient muscle fibres. in Human molecular genetics 2004
human CD1c (show CD1C Antibodies) adopts different conformations dependent on ligand occupancy of its groove, with CE and ASG (show ARSG Antibodies) stabilizing CD1c (show CD1C Antibodies) conformations that provide a footprint for binding of CD1c (show CD1C Antibodies) self-reactive T-cell receptors
There was a significant increase of blood CD1c (show CD1C Antibodies)(+) myeloid dendritic cells in autoimmune uveitis patients. The mature phenotype and function of CD1c (show CD1C Antibodies)(+) mDC1 (show MDC1 Antibodies) were regulated by TNFalpha (show TNF Antibodies) via a p38 MAPK (show MAPK14 Antibodies)-dependent pathway.
decidual CD1c (show CD1C Antibodies)(+) dendritic cells with Toxoplasma gondii infection have enhanced cytotoxicity of decidual natural killer cells
hMPV-infected BDCA-1(+) and BDCA-3 (show THBD Antibodies)(+) mDCs induced expansion of Th17 cells, in response to RSV, BDCA-1(+) mDCs induced expansion of Th1 (show TH1L Antibodies) cells and BDCA-3 (show THBD Antibodies)(+) mDCs induced expansion of Th2 cells and Tregs
mLPA-specific T cells efficiently kill CD1c (show CD1C Antibodies)(+) acute leukemia cells, poorly recognize nontransformed CD1c (show CD1C Antibodies)-expressing cells, and protect immunodeficient mice against CD1c (show CD1C Antibodies)(+) human leukemia cells.
[review] Humans express both Group 1 (CD1a (show CD1A Antibodies), CD1b (show CD1B Antibodies) and CD1c (show CD1C Antibodies)) and Group 2 (CD1d) CD1 molecules with nonredundant functions in response to the presentation of endogenous lipids.
Activated dendritic cell subsets expressing CD141 (show THBD Antibodies)/CLEA9A/CD1c (show CD1C Antibodies), likely recruited into the tubulointerstitium, are positioned to play a role in the development of fibrosis and, thus, progression to chronic kidney disease.
CD1c (show CD1C Antibodies)+ myeloid dendritic cells were increased in idiopathic pulmonary fibrosis patients versus controls.
RSV infection induces a distinct pattern of costimulatory molecule (show CD276 Antibodies) expression and cytokine production by BDCA-1(+) and BDCA-3 (show THBD Antibodies)(+) mDCs, and impairs their ability to stimulate T cell proliferation.
for isoforms CD1b (show CD1B Antibodies) through CD1e (show CD1e Antibodies), our simulations show the near-complete collapse of the hydrophobic cavities in the absence of the antigen. This event results from the spontaneous closure of the binding domain entrance, flanked by two alpha-helices.
CD1 genes were located in clusters between KIRREL and olfactory receptor (OR) genes
kyphoscoliosis peptidase (Ky), which plays a vital role in muscle growth, was also up-regulated in the transgenic mice.
KY, IGFN1 and FLNC (show FLNC Antibodies) are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.
Changes in expression of MLP (show MARCKSL1 Antibodies), MARP2 and Xin (show XIRP1 Antibodies) have been related to the onset of dystrophic and adaptive changes that operate in ky/ky muscles
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
CD1C antigen, c polypeptide
, T-cell surface glycoprotein CD1c
, cortical thymocyte antigen CD1C
, differentiation antigen CD1-alpha-3
, CD1 protein
, CD1D antigen
, antigen-presenting glycoprotein CD1d