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anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) Antibodies

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. Additionally we are shipping LAG1 Homolog, Ceramide Synthase 5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LASS5 91012 Q8N5B7
LASS5 71949 Q9D6K9
LASS5 366984  
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Top anti-LAG1 Homolog, Ceramide Synthase 5 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of LASS5 in human brain tissue with this product at 2.5 μg/ml. Western blot analysis of LASS5 in rat brain tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunofluorescence of LASS5 in human brain tissue with this product at 20 μg/ml. Western blot analysis of LASS5 in SK-N-SH lysate with this product at 1 μg/ml in the (A) absence and (B) presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Lass5 expression in Jurkat cell  lysate. Multiple isoforms of Lass5 can be detected. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with LASS5 antibody ABIN396946 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details

LASS5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LAG1 Homolog, Ceramide Synthase 5 Antibodies

  1. Human Polyclonal LASS5 Primary Antibody for EIA, IF - ABIN500138 : Riebeling, Allegood, Wang, Merrill, Futerman: Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN500138

  2. Human Polyclonal LASS5 Primary Antibody for EIA, IHC (p) - ABIN500140 : Xu, Zhou, McCoy, Mallampalli: LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia. in Journal of lipid research 2005 (PubMed)
    Show all 4 references for ABIN500140

  3. Cow (Bovine) Polyclonal LASS5 Primary Antibody for WB - ABIN2780267 : Kitatani, Idkowiak-Baldys, Bielawski, Taha, Jenkins, Senkal, Ogretmen, Obeid, Hannun: Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK. in The Journal of biological chemistry 2006 (PubMed)

  4. Human Polyclonal LASS5 Primary Antibody for WB - ABIN223496 : Yamane, Miyazawa, Moriya, Abe, Yamane et al.: D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ... in Biochimie 2011 (PubMed)

More Antibodies against LAG1 Homolog, Ceramide Synthase 5 Interaction Partners

Human LAG1 Homolog, Ceramide Synthase 5 (LASS5) interaction partners

  1. mRNA level of CerS5 is higher in cancerous cell lines and decreases following the induction of apoptosis.

  2. Overexpression of CerS5 increased apoptosis in HeLa cells.

  3. study identifies LASS5 as a genuine dihydroceramide synthase and demonstrates that mammalian dihydroceramide synthases do not require additional subunits for their activity

  4. accumulation of C(16)-ceramide in mitochondria formed from the protein kinase C (show PKC Antibodies)-dependent salvage pathway results at least in part from the action of longevity-assurance homologue 5, and the generated ceramide modulates the p38 (show CRK Antibodies) cascade via PP1 (show PPA1 Antibodies)

  5. Down-regulation of either acid sphingomyelinase (show SMPD1 Antibodies) or LASS 5-attenuated ceramide accumulation and H/R-induced Bax (show BAX Antibodies) translocation to mitochondria.

Mouse (Murine) LAG1 Homolog, Ceramide Synthase 5 (LASS5) interaction partners

  1. Ceramide synthase 5 is essential to maintain C16:0-ceramide pools and contributes to the development of diet-induced obesity.

  2. Transfection of Lass5 cDNA into or pulse of Lass5 peptide onto B7-1 (show CD80 Antibodies) positive RMA-S cells overcomes the requirement of the B7-1 (show CD80 Antibodies)/CD28 (show CD28 Antibodies) signal for T effector response.

  3. Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1 (show CERS1 Antibodies)-Cers6 (show CERS6 Antibodies)) activity in macrophages is responsible for the accumulation of ceramide.

  4. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes.

  5. Lag1p family members trh1 (show CERS4 Antibodies) and trh4 regulate (dihydro)ceramide synthases responsible for production of sphingolipids containing different fatty acids

  6. LASS5 is the major ceramide synthase gene product involved in sphingolipid production that may also regulate phosphatidylcholine (show SGMS2 Antibodies) metabolism in pulmonary epithelia

LAG1 Homolog, Ceramide Synthase 5 (LASS5) Antigen Profile

Protein Summary

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner (By similarity).

Gene names and symbols associated with LASS5

  • ceramide synthase 5 (LASS5) antibody
  • ceramide synthase 5 (cers5) antibody
  • ceramide synthase 5 (CERS5) antibody
  • LAG1 homolog, ceramide synthase 5 (LASS5) antibody
  • ceramide synthase 5 (Cers5) antibody
  • 2310081H14Rik antibody
  • AU045339 antibody
  • AW544927 antibody
  • Lass5 antibody
  • Trh4 antibody

Protein level used designations for LASS5

LAG1 homolog, ceramide synthase 5 , LAG1 longevity assurance homolog 5-like , LAG1 longevity assurance homolog 5 , TRAM homolog 4 , longevity assurance homolog 5 , translocating chain-associating membrane protein homolog 4

GENE ID SPECIES
100059999 Equus caballus
451891 Pan troglodytes
713449 Macaca mulatta
100101657 Xenopus (Silurana) tropicalis
100231332 Taeniopygia guttata
100400191 Callithrix jacchus
100454836 Pongo abelii
530776 Bos taurus
495501 Xenopus laevis
91012 Homo sapiens
71949 Mus musculus
366984 Rattus norvegicus
426879 Gallus gallus
477611 Canis lupus familiaris
Selected quality suppliers for anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) Antibodies
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