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LIM Domain Only 3 (Rhombotin-Like 2) Proteins (LMO3)

The protein encoded by LMO3 belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. Additionally we are shipping LMO3 Antibodies (25) and LMO3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LMO3 245979  
LMO3 109593 Q8BZL8
LMO3 55885 Q8TAP4
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Top LMO3 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,315.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,315.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,315.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,348.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LMO3 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , ,
,

More Proteins for LIM Domain Only 3 (Rhombotin-Like 2) (LMO3) Interaction Partners

Mouse (Murine) LIM Domain Only 3 (Rhombotin-Like 2) (LMO3) interaction partners

  1. suggested that the expression levels of Lmo3 and/or Hen2 could determine the fate of stem cells by inhibiting Hes1 function during nervous system development and might be a trigger of aberrant neurogenesis in vivo

  2. These results support a role for LMO3 in regulating behavioral responses to ethanol, potentially through its actions in the nucleus accumbens.

  3. Gbx2 (show GBX2 Proteins) regulates thalamocortical axon guidance by modifying the LIM (show PDLIM5 Proteins) and Robo codes.

  4. when tested for behavioral responses to ethanol, transgenic mice exhibited altered ethanol sedation and consumption that correlated with Lmo3 expression levels; results suggest a role for Lmo3 in ethanol-related behaviors in mice

  5. Results suggest that all four members of the LIM (show PDLIM5 Proteins)-only family -- LMO1 (show LMO1 Proteins), 2, 3, and 4 -- are important regulators of distinct developmental pathways.

  6. Data show that the calcium- and integrin-binding protein CIB (show CIB1 Proteins) as an LMO3-binding protein, which binds via the second LIM (show PDLIM5 Proteins) domain (LIM2 (show LHX2 Proteins)) of LMO3.

Human LIM Domain Only 3 (Rhombotin-Like 2) (LMO3) interaction partners

  1. MiR (show MLXIP Proteins)-101 decreased the expression of LMO3 by reversing the methylation status of the LMO3 promoter and by inhibiting the presence of the methylation-related histones H3K4me2 and H3K27me3 and increasing the presence of H3K9me3 and H4K20me3 on the promoter.

  2. LMO3 as a regulator of human adipogenesis and could contribute a mechanism resulting in visceral-fat accumulation in obesity due to excess glucocorticoids.

  3. suggest that LMO3 is a transcriptional signal transducer in NKX2-1 (show NKX2-1 Proteins)-amplified lung adenocarcinomas

  4. We confirmed that the expression of LMO3 in squamous cell carcinoma is regulated by DNA methylation (show HELLS Proteins) of its specific promoter region.

  5. The present results suggest that a transcriptional complex of LMO3 and HEN2 (show NHLH2 Proteins) may contribute to the genesis and malignant phenotype of neuroblastoma (show ARHGEF16 Proteins) by inhibiting HES1 which suppresses the transactivation of Mash1 (show ASCL1 Proteins).

  6. LMO3 acts as a co-repressor of p53 (show TP53 Proteins), suppressing p53 (show TP53 Proteins)-dependent transcriptional regulation without inhibition of its DNA-binding activity.

  7. The deregulated expression of neuronal-specific LMO3 and HEN2 (show NHLH2 Proteins) contributes to the genesis and progression of human neuroblastoma (show ARHGEF16 Proteins) in a lineage-specific manner.

LMO3 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with LMO3

  • LIM domain only 3 (rhombotin-like 2) (LMO3)
  • LIM domain only 3 (rhombotin-like 2) (LOC100224031)
  • LIM domain only 3 (lmo3)
  • LIM domain only 1 (Lmo1)
  • LIM domain only 3 (Lmo3)
  • transcription factor XLMO1 (xlmo1)
  • AI854781 protein
  • BB106490 protein
  • Bx protein
  • Dat1 protein
  • DKFZp459E083 protein
  • DKFZp459K207 protein
  • DKFZp459L014 protein
  • lmo1 protein
  • lmo3 protein
  • Rbtn-3 protein
  • RBTN3 protein
  • RBTNL2 protein
  • Rhom-3 protein
  • RHOM3 protein
  • zgc:110149 protein

Protein level used designations for LMO3

LIM domain only protein 3 , LIM domain only 3 (rhombotin-like 2) , LIM domain only 3 , lim domain only protein 3 , LMO-3 , neuronal-specific transcription factor DAT1 , dopamine-inducible LIM-domain transcription factor DAT1 , LIM only 3 , lmo3b , rhombotin-3 , LIM domain only protein 1 , LMO-1

GENE ID SPECIES
100127154 Sus scrofa
100174731 Pongo abelii
100224031 Taeniopygia guttata
100528645 Ictalurus punctatus
245979 Rattus norvegicus
109593 Mus musculus
553774 Danio rerio
55885 Homo sapiens
532870 Bos taurus
399311 Xenopus laevis
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