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anti-LIM Domains Containing 1 (LIMD1) Antibodies

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Additionally we are shipping LIMD1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LIMD1 494021  
LIMD1 8994 Q9UGP4
LIMD1 29806 Q9QXD8
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Top anti-LIMD1 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB LIMD1 Antibody (C-term) (ABIN657056) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Tonsil, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p) AP23796PU LIMD1 antibody staining of Human Lung. 1 mL Log in to see 6 to 8 Days
$599.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image LIMD1 antibody [C2C3], C-term detects LIMD1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: LIMD1 protein stained by LIMD1 antibody [C2C3], C-term , diluted at 1:500. Blue: Hoechst 33342 staining. IHC-P Image Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using LIMD1, antibody at 1:300 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LIMD1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged LIMD1 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details

LIMD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LIMD1 Antibodies

  1. Mouse (Murine) Polyclonal LIMD1 Primary Antibody for IHC (p), WB - ABIN657056 : Ghosh, Ghosh, Maiti, Mukherjee, Dutta, Roy, Roychoudhury, Panda: LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications. in Molecular cancer 2010 (PubMed)
    Show all 4 references for ABIN657056

More Antibodies against LIMD1 Interaction Partners

Human LIM Domains Containing 1 (LIMD1) interaction partners

  1. Thus, the LIMD1-MYBL1 (show MYBL1 Antibodies) Index had considerable clinical value for DLBCL subtype classification and prognosis.

  2. Cyclic stretch is associated with a JNK (show MAPK8 Antibodies)-dependent increase in binding of a LATS (show LATS1 Antibodies) inhibitor, LIMD1, to the LATS1 (show LATS1 Antibodies) kinase and that reduction of LIMD1 expression suppresses the activation of YAP (show YAP1 Antibodies) by cyclic stretch.

  3. LIMD1 prevents retinoblastoma phosphorylation and downregulates of E2F1 (show E2F1 Antibodies) protein and blocks entry of cells into S-phase.

  4. Data show that the tumour suppressor protein LIMD1 acts as a molecular scaffold, simultaneously binding the PHDs and VHL (show VHL Antibodies), thereby assembling a PHD (show PDC Antibodies)-LIMD1-VHL (show VHL Antibodies) protein complex and creating an enzymatic niche that enables efficient degradation of HIF-1alpha (show HIF1A Antibodies).

  5. PU.1 is a major transcriptional activator of LIMD1

  6. LIMD1 inactivation as primary event than inactivation of RB1 (show RB1 Antibodies) in head and neck squamous cell carcinoma development.

  7. LIMD1 is a tumor-suppressor gene, the protein product of which functionally interacts with pRB (show RB1 Antibodies) and the loss of which promotes lung carcinogenesis

  8. These results suggest that some breast tumors have altered expression of LIMD1 RNA and that LIMD1 may be involved in cell anchoring via focal adhesions and in the cell cycle, particularly during mitosis.

  9. study demonstrates that LIMD1 represents a novel prognostic marker for breast cancer. Combined with the fact that LIMD1 expression is downregulated in lung cancers this clearly indicates that LIMD1 may represent a critical tumor suppressor gene

  10. LIMD1 is a validated chromosome 3p21.3 tumor-suppressor gene involved in human lung cancer development.

Mouse (Murine) LIM Domains Containing 1 (LIMD1) interaction partners

  1. Limd1 regulates AP-1 (show JUN Antibodies) activation through an interaction with Traf6 (show TRAF6 Antibodies) to influence osteoclast development

  2. Limd1 influences not only stress osteoclastogenesis but also osteoblast function and osteoblast progenitor commitment. Together, these data identify Limd1 as a novel regulator of both bone osetoclast and bone osteoblast development and function.

LIMD1 Antigen Profile

Protein Summary

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG- dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1- responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation (By similarity).

Gene names and symbols associated with LIMD1

  • LIM domains containing 1 (limd1) antibody
  • LIM and cysteine-rich domains 1 (Lmcd1) antibody
  • LIM domains containing 1 (LIMD1) antibody
  • LIM domains containing 1 (Limd1) antibody
  • AW822033 antibody
  • D9Ertd192e antibody
  • LIMD1 antibody
  • xlimd1 antibody

Protein level used designations for LIMD1

LIM domain-containing protein 1 , LIM and cysteine-rich domains protein 1 , dyxin , LIM domains-containing protein 1

GENE ID SPECIES
549360 Xenopus (Silurana) tropicalis
494021 Rattus norvegicus
779085 Xenopus laevis
8994 Homo sapiens
484796 Canis lupus familiaris
29806 Mus musculus
617525 Bos taurus
316101 Rattus norvegicus
420701 Gallus gallus
100738579 Sus scrofa
Selected quality suppliers for anti-LIMD1 (LIMD1) Antibodies
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