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Laeverin Proteins (AQPEP)

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. Additionally we are shipping AQPEP Kits (3) and AQPEP Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat AQPEP AQPEP 502160  
AQPEP 206338 Q6Q4G3
AQPEP 74574  
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Top AQPEP Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

AQPEP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Laeverin (AQPEP) Interaction Partners

Human Laeverin (AQPEP) interaction partners

  1. In preeclamptic placentas, laeverin is experssed in the cytoplasm and microvesicles, rather than the cell membrane. Laeverin appears to be involved in trophoblast cell migration and invasion through interaction with integrins and matrix metalloprotease 1 (show MMP1 Proteins).

  2. Laeverin is a specific cell-surface marker for human extravillous trophoblast (EVT) and plays a regulatory role in EVT migration.

  3. Replacement of glutamine-238 with alanine caused a significant change in substrate specificity rather than a decrease in enzymatic activity.

  4. These results indicate that His(379) of laeverin plays essential roles in its distinctive enzymatic properties and contributes to maintaining the appropriate structure of the catalytic cavity of the enzyme.

  5. Extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases(laeverin)

  6. The 3 most significantly overexpressed genes in rheumatoid arthritis were laeverin, 11beta-hydroxysteroid dehydrogenase type 2 (a steroid pathway enzyme), and cysteine-rich, angiogenic inducer 61 (a known angiogenic factor (show VEGFA Proteins)).

  7. is a novel bestatin-sensitive leucine aminopeptidase (show LAP Proteins); plays important roles in human placentation by regulating biological activity of key peptides at the embryo-maternal interface

  8. A novel membrane-bound cell surface peptidase, laeverin (FLJ90650), was found to be specifically expressed on extravillous trophoblasts that had almost ceased invasion into maternal decidual tissues.

AQPEP Protein Profile

Protein Summary

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met- MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.

Gene names and symbols associated with Laeverin Proteins (AQPEP)

  • laeverin (Aqpep)
  • laeverin (AQPEP)
  • laeverin (LVRN)
  • laeverin (LOC100353757)
  • RIKEN cDNA 4833403I15 gene (4833403I15Rik)
  • APQ protein
  • Aqpep protein
  • LVRN protein
  • RGD1562779 protein

Protein level used designations for Laeverin Proteins (AQPEP)

aminopeptidase Q , laeverin , AP-Q , CHL2 antigen

GENE ID SPECIES
502160 Rattus norvegicus
525695 Bos taurus
696886 Macaca mulatta
100353757 Oryctolagus cuniculus
206338 Homo sapiens
74574 Mus musculus
Selected quality suppliers for AQPEP Proteins (AQPEP)
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