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Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.. Additionally we are shipping Laminin alpha 1 Kits (14) and Laminin alpha 1 Proteins (8) and many more products for this protein.
Showing 10 out of 56 products:
Human Polyclonal Laminin alpha 1 Primary Antibody for IF, ELISA - ABIN1534451
Haaparanta, Uitto, Ruoslahti, Engvall: Molecular cloning of the cDNA encoding human laminin A chain. in Matrix (Stuttgart, Germany) 1991
The distribution of laminin and alphaSMA (show ACTA2 Antibodies) in the testis and epididymis might point out to their roles in the male reproduction.
Analysis of zebrafish laminin-alpha 1 mutants reveals multiple functions for laminin-alpha 1 in the outgrowth and guidance of central nervous system axons
Laminin alpha 1 is needed for lens development in zebrafish embryos.
The phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye defects and shortened body axis, is reported.
two guidance cues, TAG-1 (show CNTN2 Antibodies) and laminin-alpha1, influence the behavior of growth cones during axon pathfinding in vivo
tag1 (show CNTN2 Antibodies), lama1 and vangl2 (show VANGL2 Antibodies) participate in a common mechanism that integrates signaling between the FBMN and its environment to regulate migration.
Taken together, these findings suggest that miR (show MLXIP Antibodies)-202 may function as a novel tumor suppressor in ESCC by repressing cell proliferation and migration, and its biological effects may attribute the inhibition of LAMA1-mediated FAK (show PTK2 Antibodies)-PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies) signaling.
Our results indicate that invasion of cervical cancer is accomplished by the remodeling of the interstitial stroma, which process includes decrease and partial replacement of fibronectin (show FN1 Antibodies) and collagens by a laminin-rich matrix
Novel PMCA3 (show ATP2B3 Antibodies) missense mutation co-occurring with a heterozygous mutation in LAMA1 impaired cellular Ca2 (show CA2 Antibodies)+ homeostasis in patients with Cerebellar Ataxia (show USP14 Antibodies).
Identification of biallelic mutations in LAMA1 as the cause of cerebellar dysplasia with cysts in seven affected individuals.
Studies indicate that progenitor endothelial cells (ECs), endothelial colony-forming cells (ECFCs), deposit collagen IV (show COL4 Antibodies), fibronectin (show FN1 Antibodies), and laminin.
miR (show MLXIP Antibodies)-9 negatively controls lamin A (show LMNA Antibodies) and progerin expression in neural cells.
we report associations with the LAMA1 and HMG20A (show HMG20A Antibodies) (not previously associated at genome-wide significance in Europeans) gene regions with type 2 diabetes risk
Laminin-alpha1 LG4-5 domain binding to dystroglycan (show DAG1 Antibodies) mediates muscle cell survival, growth, and the AP-1 (show FOSB Antibodies) and NF-kappaB (show NFKB1 Antibodies) transcription factors but also has adverse effects.
The polymorphism of SNP rs2089760, located in the promoter region of LAMA1, may be associated with high myopia in the Chinese population.
c-Jun/AP-1 (show JUN Antibodies) activity mediated by JNK (show MAPK8 Antibodies), PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) pathways is required for laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells.
Laminin regulates PDGFRbeta cell differentiation, fate determination, cell stemness and muscle development via gpihbp1 (show GPIHBP1 Antibodies).
while MMP-9 (show MMP9 Antibodies) is not essential for hypoxic-induced cerebral angiogenesis, it plays an important role in post-hypoxic vascular pruning by degrading laminin and claudin-5 (show CLDN5 Antibodies)
interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 activates alpha6beta1/CD151 (show CD151 Antibodies) signaling which programs ESCs (show NR2E3 Antibodies) toward the endothelial cells lineage fate
These findings suggest that LAMA1 plays a critical role in kidney function and kidney aging by regulating the mesangial cell population and mesangial matrix deposition through TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling.
Mutations in Lama1 allow developing retinal vessels to enter the vitreous where they anastomose with vessels of the hyaloid system which persist and expand
Our data show that the absence of Lama1 has an impact on the Bergmann glia scaffold that aberrantly develops.
Laminin alpha1 chain is not responsible for muscle disease in the mdx (show DMD Antibodies) mouse model for Duchenne muscular dystrophy (show DMD Antibodies)
This first report of viable Lama1 mouse mutants emphasizes the importance of this gene in retinal development, and data suggest that hypomorphic mutations in human LAMA1 could lead to retinal disease.
Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 (show MMP9 Antibodies) expression.
mouse laminin alpha 1 gene has an upstream enhancer that defines its expression in parietal endoderm cells
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
laminin subunit alpha-1
, laminin, alpha 1
, laminin subunit alpha-1-like
, S-LAM alpha
, S-laminin subunit alpha
, laminin A chain
, laminin-3 subunit alpha
, laminin-1 subunit alpha