Lectin, Galactoside-Binding, Soluble, 9 Proteins (LGALS9)

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 9 Antibodies (194) and Lectin, Galactoside-Binding, Soluble, 9 Kits (53) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LGALS9 16859 O08573
LGALS9 3965 O00182
LGALS9 25476 P97840
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Lectin, Galactoside-Binding, Soluble, 9 Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$103.27
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$420.00
Details
HOST_HEK-293 Cells Human His tag Human Galectin-9, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 5 Days
$319.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,964.50
Details

LGALS9 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , , , ,
, , , , ,
Rat (Rattus) ,

Top referenced Lectin, Galactoside-Binding, Soluble, 9 Proteins

  1. Human LGALS9 Protein expressed in HEK-293 - ABIN2666753 : Bacigalupo, Manzi, Rabinovich, Troncoso: Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma. in World journal of gastroenterology : WJG 2013 (PubMed)
    Show all 7 references for 2666753

  2. Human LGALS9 Protein expressed in Escherichia coli (E. coli) - ABIN667765 : Türeci, Schmitt, Fadle, Pfreundschuh, Sahin: Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for 667765

  3. Mouse (Murine) LGALS9 Protein expressed in Escherichia coli (E. coli) - ABIN1098734 : Hirashima, Kashio, Nishi, Yamauchi, Imaizumi, Kageshita, Saita, Nakamura: Galectin-9 in physiological and pathological conditions. in Glycoconjugate journal 2004 (PubMed)
    Show all 2 references for 1098734

  4. Human LGALS9 Protein expressed in Wheat germ - ABIN1309346 : Qi, Song, Shen, Xu, Shen, Luo, Zhong, Wang, Chu, Song: Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice. in Immunology letters 2012 (PubMed)

More Proteins for Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. Galectin 9 is a novel dectin 1 (show CLEC7A Proteins) ligand in pancreatic ductal adenocarcinoma. Upon disruption of the dectin 1 (show CLEC7A Proteins)-galectin 9 axis, CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells, which are dispensable for PDA progression in hosts with an intact signaling axis, become reprogrammed into indispensable mediators of anti-tumor immunity.

  2. The Gal-9/Tim-3 (show HAVCR2 Proteins) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  3. These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.

  4. galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.

  5. Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury

  6. Gal-9, a natural TIM-3 (show HAVCR2 Proteins) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.

  7. Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (show HAVCR2 Proteins) independent manner.

  8. galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (show TGFB1 Proteins) to enforce iTreg cell differentiation and maintenance.

  9. Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

  10. action of agonist anti-4-1BB (show TNFRSF9 Proteins) in suppressing autoimmune and allergic inflammation was completely dependent on Galectin-9 (Gal-9). Gal-9 directly bound to 4-1BB (show TNFRSF9 Proteins), in a site distinct from the binding site of antibodies and the natural ligand of 4-1BB (show TNFRSF9 Proteins)

Human Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. Galectin 9 is a novel dectin 1 (show CLEC7A Proteins) ligand in pancreatic ductal adenocarcinoma. Upon disruption of the dectin 1 (show CLEC7A Proteins)-galectin 9 axis, CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells, which are dispensable for PDA progression in hosts with an intact signaling axis, become reprogrammed into indispensable mediators of anti-tumor immunity.

  2. X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site has been presented.

  3. These findings may indicate that an increase in the Gal-9 level, a novel immune checkpoint molecule, can reflect immune-related adverse effects of various biotherapies.

  4. Our data suggest a role of galectin-9 in regulating HIV transcription and viral production in vivo during therapy

  5. these data suggest that the high Tim-3 (show HAVCR2 Proteins) expression in monocytes could be utilized by tumor-promoting Gal-9 expression on CD4 (show CD4 Proteins)(+) T cells

  6. this study shows that in osteosarcoma patients, Tim3 (show HAVCR2 Proteins) expression did not directly mediate immune suppression, but the interaction between Tim3 (show HAVCR2 Proteins)+ T cells and monocytes, naive CD4 (show CD4 Proteins)+ T cells, and Gal9-expressing CD4 (show CD4 Proteins)+ CD25 (show IL2RA Proteins)+ Tregs could resulting in progressive suppression of Th1 (show TH1L Proteins) responses

  7. The human recombinant galectin-9 has demonstrated anti-cancer activities, including inducing apoptosis in hematological, dermatological and gastrointestinal malignancies. In this review, the molecular characteristics, history and apoptosis-inducing potential of galectin-9 are described. [review]

  8. Results showed that in acute febrile phase, galectin-9 and galectin-3BP were induced in dengue patients compared to healthy controls suggesting that both molecules might be important inflammatory mediators in acute dengue virus infection.

  9. In this review, we summarize the latest knowledge on the structure, receptors, cellular targets, trafficking pathways and functional properties of galectin-9 and discuss how galectin-9-mediated signalling cascades can be exploited in cancers and immunotherapies

  10. this study shows that the levels of expression of Gal-9 on CD4 (show CD4 Proteins)+ T cells, CD8 (show CD8A Proteins)+ T cells, CD56 (show NCAM1 Proteins)+ T cells and in serum in patients with systemic lupus erythematosus are significantly higher than those of healthy controls

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. The Tim-3 (show HAVCR2 Proteins)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 mRNA would display a differential expression pattern in the endometrium.

Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) Protein Profile

Protein Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with LGALS9

  • lectin, galactoside-binding, soluble, 9 (lgals9)
  • zgc:92326 (zgc:92326)
  • lectin, galactoside-binding, soluble, 9 (LGALS9)
  • galectin-9 (LOC100350347)
  • galectin-9-like (LOC100728329)
  • lectin, galactose binding, soluble 9 (Lgals9)
  • lectin, galactoside-binding, soluble, 9 (Lgals9)
  • AA407335 protein
  • AI194909 protein
  • AI265545 protein
  • ecalectin protein
  • gal-9 protein
  • galectin-9 protein
  • HUAT protein
  • Lgals5 protein
  • LGALS9 protein
  • LGALS9A protein
  • LGALS35 protein
  • UAT protein
  • UATP.I protein
  • wu:fd20c09 protein
  • zgc:111833 protein

Protein level used designations for LGALS9

lectin, galactoside-binding, soluble, 9 , galactoside-binding soluble lectin 9 , galectin 9 , lectin, galactoside-binding, soluble, 9 (galectin 9) , galectin-9 , lectin, galactose binding, soluble 5 , ecalectin , gal-9 , tumor antigen HOM-HD-21 , urate transporter/channel protein , 36 kDa beta-galactoside-binding lectin , Lectin galactose binding soluble 9 (Galectin-9) , Lectin, galactose binding, soluble 9 (Galectin-9) , UAT , urate transporter/channel , urate transporter , urate transporter/channel protein, isoform (UATp,i)

GENE ID SPECIES
733366 Xenopus laevis
100145704 Xenopus (Silurana) tropicalis
327284 Danio rerio
454519 Pan troglodytes
100350347 Oryctolagus cuniculus
100728329 Cavia porcellus
16859 Mus musculus
3965 Homo sapiens
25476 Rattus norvegicus
442861 Canis lupus familiaris
396972 Sus scrofa
510813 Bos taurus
Selected quality suppliers for Lectin, Galactoside-Binding, Soluble, 9 Proteins (LGALS9)
Did you look for something else?