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Leucine Rich Repeat and Ig Domain Containing 1 Proteins (LINGO1)

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). Additionally we are shipping LINGO1 Antibodies (115) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LINGO1 84894 Q96FE5
LINGO1 235402 Q9D1T0
Rat LINGO1 LINGO1 315691  
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Top LINGO1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LINGO1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) Interaction Partners

Human Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. LINGO1 rs11856808 plays a protective role by decreasing the risk for PD, but not for MSA (show TPO Proteins), in Chinese population.

  2. LINGO1 protein acts as a gateway protein internalizing into the tumor cells when engaged by antibody and can carry antibody conjugated with drugs to kill Ewing sarcoma cells.

  3. Data indicate that leucine-rich repeat neuronal protein 1 (LINGO-1) is intracellular and competes with Nogo-66 receptor (NgR (show RTN4R Proteins)) for binding to p75 neurotrophin receptor (p75NTR (show NGFR Proteins)).

  4. The results of this study show Increased LINGO1 in the cerebellum of essential tremor patients.

  5. Lingo-1 signaling is altered in the schizophrenia brain.

  6. LINGO-1 can directly bind to ErbB2 (show ERBB2 Proteins), block ErbB2 (show ERBB2 Proteins) translocation into lipid rafts, and inhibit its phosphorylation.

  7. This review found that several gene variants in the LINGO1 gene may increase the risk of essential tremor.

  8. LINGO1 variants are associated with essential tremor in Chinese Han female patients.

  9. LINGO-1 potentiates neuronal apoptosis, likely by inhibiting WNK3 kinase activity.

  10. Results of a meta-analysis suggest a relationship between LINGO1 rs11856808 polymorphism and risk of essential tremor (ET) and familial ET, while rs9652490 polymorphism is only associated with the risk for familial ET.

Mouse (Murine) Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. These data provide morphometric and functional evidence of enhancement of remyelination associated with antagonism of LINGO-1

  2. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions

  3. a novel role for LINGO-1 in neural stem cell differentiation to neurons

  4. inhibitory agents of LINGO-1 activity can protect dopaminergic neurons against degeneration

  5. Lingo1 antagonist promotes spinal cord remyelination and axonal integrity in MOG (show MOG Proteins)-induced experimental autoimmune encephalomyelitis.

LINGO1 Protein Profile

Protein Summary

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity).

Gene names and symbols associated with LINGO1

  • leucine rich repeat and Ig domain containing 1 (LINGO1)
  • leucine rich repeat and Ig domain containing 1 (lingo1)
  • leucine rich repeat and Ig domain containing 1 (LOC100228050)
  • leucine rich repeat and Ig domain containing 1 (Lingo1)
  • 4930471K13Rik protein
  • AV148400 protein
  • DKFZp459P0736 protein
  • LERN1 protein
  • LINGO-1 protein
  • Lrrn6a protein
  • UNQ201 protein

Protein level used designations for LINGO1

leucine rich repeat and Ig domain containing 1 , leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , leucine rich repeat neuronal 6A , leucine-rich repeat and immunoglobilin domain-containing protein 1 , leucine-rich repeat and immunoglobulin domain-containing protein 1 , leucine-rich repeat neuronal protein 1 , leucine-rich repeat neuronal protein 6A , leucine-rich repeat neuronal 6A , cLINGO-1

GENE ID SPECIES
453764 Pan troglodytes
100061441 Equus caballus
100101739 Xenopus (Silurana) tropicalis
100171931 Pongo abelii
100228050 Taeniopygia guttata
84894 Homo sapiens
235402 Mus musculus
415344 Gallus gallus
487660 Canis lupus familiaris
100155465 Sus scrofa
520694 Bos taurus
315691 Rattus norvegicus
Selected quality suppliers for LINGO1 Proteins (LINGO1)
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